Site-Specific, Sustained Release of Drugs to the Brain

Chemistry of dihydropyridines

1972 • 790 citations

Delivery of a Quaternary Pyridinium Salt Across the Blood-Brain Barrier by Its Dihydropyridine Derivative

1975 • 71 citations

Improved delivery through biological membranes. 1. Synthesis and properties of 1-methyl-1,6-dihydropyridine-2-carbaldoxime, a pro-drug of N-methylpyridinium-2-carbaldoxime chloride

1976 • 61 citations

Improved delivery through biological membranes. 3. Delivery of N-methylpyridinium-2-carbaldoxime chloride through the blood-brain barrier in its dihydropyridine pro-drug form

1976 • 51 citations

Conformations, DNA binding parameters, and antileukemic activity of certain cytotoxic protoberberine alkaloids

1979 • 43 citations

Improved delivery through biological membranes. 2. Distribution, excretion, and metabolism of N-methyl-1,6-dihydropyridine-2-carbaldoxime hydrochloride, a pro-drug of N-methylpyridinium-2-carbaldoxime chloride

1976 • 34 citations

Elimination of a Quaternary Pyridinium Salt Delivered as Its Dihydropyridine Derivative from Brain of Mice

1978 • 32 citations

Ueber Dihydroberberin

1910 • 9 citations