The Value of Improving the Productivity of the Drug Development Process

The price of innovation: new estimates of drug development costs

2003 • 4,276 citations

Cost of innovation in the pharmaceutical industry

1991 • 774 citations

Risks in new drug development: Approval success rates for investigational drugs

2001 • 457 citations

Returns on Research and Development for 1990s New Drug Introductions

2002 • 312 citations

New drug development in the United States from 1963 to 1999

2001 • 255 citations

New Drug Innovation and Pharmaceutical Industry Structure: Trends in the Output of Pharmaceutical Firms

2000 • 77 citations

Emerging Role of Pharmacoeconomics in the Research and Development Decision-Making Process

2001 • 66 citations

Measuring the Pace of New Drug Development in the User Fee ERA

2000 • 50 citations

The New Drug Approvals of 1996, 1997, and 1998: Drug Development Trends in the User Fee Era

2000 • 47 citations

Initiatives to Speed New Drug Development and Regulatory Review: The Impact of FDA-Sponsor Conferences

1997 • 20 citations

FIGHTING THE CLOCK

2002 • 11 citations

GASES OF A LESSER NOBILITY

2002 • 10 citations

Fast Track Product Designation under the Food and Drug Administration Modernization Act: The Industry Experience

2001 • 10 citations