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Increased Intracellular cAMP Renders HL-60 Cells Resistant to Cytotoxicity of Taxol

Data up to Jan 2025

Published1999
Citations8
References20

Total Citations Per Year

Abstract

References (20)

Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

1971 • 3,891 citations

Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer

1996 • 2,766 citations

Taxol stabilizes microtubules in mouse fibroblast cells.

1980 • 1,942 citations

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

1993 • 1,086 citations

THE IMPACT OF NATIONAL CANCER ACT

1991 • 809 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Phase II Study of Taxol in Patients With Untreated Advanced Non-Small-Cell Lung Cancer

1993 • 441 citations

Taxol: Mechanisms of Action and Resistancea

1986 • 415 citations

Substoichiometric Binding of Taxol Suppresses Microtubule Dynamics

1995 • 331 citations

Characterization of the Taxol Binding Site on the Microtubule

1995 • 229 citations

Priming of human myeloid leukemic cell lines HL-60 and U-937 with retinoic acid for differentiation effects of cyclic adenosine 3':5'-monophosphate-inducing agents and a T-lymphocyte-derived differentiation factor.

1982 • 181 citations

Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma.

1994 • 164 citations

A phosphoglycoprotein associated with taxol resistance in J774.2 cells.

1985 • 158 citations

Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines.

1988 • 99 citations

Acquisition of taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells

1997 • 86 citations

Novel mechanism of resistance to paclitaxel (Taxol) in human K562 leukemia cells by combined selection with PSC 833.

1995 • 83 citations

Differential expression and activity of phosphatases and protein kinases in adriamycin sensitive and resistant human breast cancer MCF-7 cells.

1998 • 27 citations

Analysis of MDR1 expression in normal and malignant endometrium by reverse transcription-polymerase chain reaction and immunohistochemistry.

1996 • 21 citations

Cisplatin resistance in cyclic AMP-dependent protein kinase mutants

1998 • 21 citations

Relationship between differentiation mechanisms involving cAMP-dependent protein kinase and protein kinase C in uninduced and differentiating HL-60 cells.

1997 • 6 citations

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Increased Intracellular cAMP Renders HL-60 Cells Resistant to Cytotoxicity of Taxol (1999) – Immunopharmacology and Immunotoxicology | Metascience Observatory Explorer