Cyclic Strain–Mediated Regulation of Vascular Endothelial Occludin and ZO-1

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A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Occludin: a novel integral membrane protein localizing at tight junctions.

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Laminar Shear Stress

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THE CELL BIOLOGY OF THE BLOOD-BRAIN BARRIER

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Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

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Rottlerin, a Novel Protein Kinase Inhibitor

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Occludin as a possible determinant of tight junction permeability in endothelial cells

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Effects of Mechanical Forces on Signal Transduction and Gene Expression in Endothelial Cells

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Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation

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Regulation of tight junctions and loss of barrier function in pathophysiology

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A new vacuum-operated stress-providing instrument that applies static or variable duration cyclic tension or compression to cells in vitro

1985 • 402 citations

Tyrosine phosphorylation and dissociation of occludin–ZO-1 and E-cadherin–β-catenin complexes from the cytoskeleton by oxidative stress

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Tyrosine phosphorylation and cadherin/catenin function

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Phosphorylation of occludin correlates with occludin localization and function at the tight junction

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Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin

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Regulation of cadherin-mediated cell–cell adhesion by the Rho family GTPases

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Tight junctions

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Biogenesis of tight junctions: The c-terminal domain of occludin mediates basolateral targeting

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Tyrosine phosphorylation of occludin attenuates its interactions with ZO-1, ZO-2, and ZO-3

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Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition

1999 • 171 citations

Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation*

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Role of Phosphatidylinositol 3-Kinase in Oxidative Stress-induced Disruption of Tight Junctions

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Localization and differential expression of two isoforms of the tight junction protein ZO-1

1992 • 168 citations

Hydrogen peroxide-induced alterations of tight junction proteins in bovine brain microvascular endothelial cells

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Targets for pharmacological intervention of endothelial hyperpermeability and barrier function

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Involvement of a Heterotrimeric G Protein α Subunit in Tight Junction Biogenesis

1996 • 136 citations

Shear stress regulates occludin content and phosphorylation

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The endothelium: vascular control of haemostasis

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Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation

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Simultaneous activation of several second messengers in hypoxia‐induced hyperpermeability of brain derived endothelial cells

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Shear Stress Regulates Occludin and VEGF Expression in Porcine Arterial Endothelial Cells

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Tyrosine phosphatase inhibition induces loss of blood–brain barrier integrity by matrix metalloproteinase-dependent and -independent pathways

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Histamine reduces ZO-1 tight-junction protein expression in cultured retinal microvascular endothelial cells

1996 • 95 citations

Shear Stress and Cyclic Strain Modulation of Gene Expression in Vascular Endothelial Cells

1995 • 92 citations

Protein Kinase C-α Activity Modulates Transepithelial Permeability and Cell Junctions in the LLC-PK1 Epithelial Cell Line

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Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy,isolation, and characterization.

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Shear-Induced Reorganization of Endothelial Cell Cytoskeleton and Adhesion Complexes

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Endothelial junctional protein redistribution and increased monolayer permeability in human umbilical vein endothelial cells isolated during preeclampsia

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Antithrombotic and prothrombotic activities of the vascular endothelium

2000 • 68 citations

Connexin-Occludin Chimeras Containing the Zo-Binding Domain of Occludin Localize at Mdck Tight Junctions and Nrk Cell Contacts

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Subtype-Specific Kinetics of Inhibitory Adenosine Receptor Internalization Are Determined by Sensitivity to Phosphorylation by G Protein-Coupled Receptor Kinases

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Analysis of the C-Terminal Tail of the Rat Thyrotropin-Releasing Hormone Receptor-1 in Interactions and Cointernalization with β-Arrestin 1-Green Fluorescent Protein

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Micro- and macrovascular endothelial cells in beta-adrenergic regulation of transendothelial permeability

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Lipoprotein(a) and the link between atherosclerosis and thrombosis.

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Cyclic Pressure Modulates Endothelial Barrier Function

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Regulation of Endopeptidases EC3.4.24.15 and EC3.4.24.16 in Vascular Endothelial Cells by Cyclic Strain: Role of Gi Protein Signaling

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Isoform-specific knockout of endothelial myosin light chain kinase: closing the gap on inflammatory lung disease

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Two exonic elements in the flanking constitutive exons control the alternative splicing of the α exon of the ZO-1 pre-mRNA

2003 • 8 citations