Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of the central nervous system in Drosophila

The Genetics and Biology of Drosophila

1978 • 3,910 citations

Animal tissue techniques

1962 • 3,769 citations

Genetic variations of Drosophila melanogaster

1967 • 2,612 citations

Developmental Neurobiology

1978 • 1,211 citations

Animal Tissue Techniques

1980 • 1,206 citations

Gonadal Steroid Induction of Structural Sex Differences in the Central Nervous System

1984 • 1,170 citations

Atlas of an insect brain

1976 • 985 citations

Zinc fingers: Gilt by association

1988 • 799 citations

The optic lobe of Drosophila melanogaster. I. A Golgi analysis of wild-type structure

1989 • 721 citations

Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster

1988 • 720 citations

Temporal Control of Puffing Activity in Polytene Chromosomes

1974 • 632 citations

Staging the metamorphosis of Drosophila melanogaster

1981 • 530 citations

The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.

1990 • 483 citations

The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers.

1991 • 440 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

Hormone Action at the Cellular Level

1985 • 297 citations

Metamorphosis, a problem in developmental biology

1982 • 295 citations

Neural reorganization during metamorphosis of the corpora pedunculata in Drosophila melanogaster

1982 • 273 citations

Actions of Estrogens and Progestins on Nerve Cells

1983 • 261 citations

Patterns of cell division and cell movement in the formation of the imaginal nervous system in Drosophila melanogaster

1978 • 251 citations

Biochemical effects of corticosteroids on neural tissues

1985 • 248 citations

Interactions and developmental effects of mutations in the Broad-Complex of Drosophila melanogaster.

1988 • 229 citations

Proliferation pattern and early differentiation of the optic lobes in Drosophila melanogaster

1990 • 220 citations

The genetics of Drosophila

1988 • 218 citations

Serotonin‐containing neurons in Drosophila melanogaster: Development and distribution

1988 • 209 citations

Mutant Alleles at the Locus elav in Drosophila melanogaster lead to Nervous System Defects. A Developmental-Genetic Analysis

1985 • 203 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

Postmetamorphic cell death in the nervous and muscular systems of Drosophila melanogaster

1990 • 193 citations

Vision in Drosophila: Genetics of Microbehavior

2011 • 178 citations

Catecholamine‐containing neurons in Drosophila melanogaster: Distribution and development

1988 • 176 citations

Independent steroid control of the fates of motoneurons and their muscles during insect metamorphosis

1985 • 172 citations

Neuropeptide‐Fmrfamide‐Like immunoreactivity in drosophila: Development and distribution

1986 • 164 citations

The influence of retinal innervation on neurogenesis in the first optic ganglion of drosophila

1991 • 163 citations

A genetic analysis of visual system development in Drosophilia melanogaster

1978 • 162 citations

The recovery and preliminary characterization of X chromosome mutants affecting imaginal discs ofDrosophila melanogaster

1972 • 157 citations

Cell degeneration in the developing optic lobes of the sine oculis and small-optic-lobes mutants of Drosophila melanogaster

1984 • 153 citations

Cytogenetic analysis of the 2B3-4-2B11 Region of the X-chromosome of Drosophila melanogaster

1980 • 140 citations

Puffs, genes, and hormones revisited

1990 • 133 citations

Postembryonic Development and Regeneration of the Insect Nervous System

1970 • 121 citations

The ecdysone-induced puffing cascade in Drosophila salivary glands: a Broad-Complex early gene regulates intermolt and late gene transcription.

1991 • 114 citations

The effect of reduction in numbers of ommatidia upon the brain of Drosophila melanogaster

1943 • 107 citations

Pre-existing neuronal pathways in the developing optic lobes of Drosophila

1989 • 105 citations

Neurobiology of Sensory Systems

1989 • 105 citations

Cytogenetic analysis of the 2B3-4-2B11 Region of the X chromosome of Drosophila melanogaster

1981 • 104 citations

Postembryonic Neuronal Plasticity and its Hormonal Control During Insect Metamorphosis

1990 • 98 citations

Neural cell types surviving congenital sensory deprivation in the optic lobes of Drosophila melanogaster

1983 • 94 citations

A trans-acting regulatory product necessary for expression of the Drosophila melanogaster 68C glue gene cluster

1984 • 90 citations

Changes in the blood-brain barrier of the central nervous system in the blowfly during development, with special reference to the formation and disaggregation of gap and tight junctions

1978 • 88 citations

Changes in the blood-brain barrier of the central nervous system in the blowfly during development, with special reference to the formation and disaggregation of gap and tight junctions

1978 • 80 citations

JUVENILE HORMONE IN RELATION TO THE LARVAL-PUPAL TRANSFORMATION OF THE CECROPIA SILKWORM

1972 • 76 citations

Development of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin

1986 • 75 citations

Molecular analysis of the ecdysterone-inducible 2B5 ‘early’ puff in Drosophila melanogaster.

1986 • 73 citations

DEVELOPMENT OF THE NERVOUS SYSTEM

1952 • 73 citations

Postembryonic neurogenesis in the CNS of the tobacco hornworm, Manduca sexta. II. Hormonal control of imaginal nest cell degeneration and differentiation during metamorphosis

1987 • 71 citations

Expansion of the central arborizations of persistent sensory neurons during insect metamorphosis: the role of the steroid hormone, 20- hydroxyecdysone

1989 • 68 citations

Genetic and developmental analysis of puparium formation in Drosophila

1978 • 67 citations

Prepupal larval mosaics in Drosophila melanogaster

1976 • 66 citations

Brain Structure and Behavior in Insects

1975 • 66 citations

GENETIC ANALYSIS OF MUTATIONS AT THE GLUED LOCUS AND INTERACTING LOCI IN DROSOPHILA MELANOGASTER

1982 • 64 citations

Das relative postembryonale wachstum der hirnteile von culex pipiens, drosophila melanogaster und drosophila-mutanten

1961 • 60 citations

The Structural Brain MutantVacuolar medullaofDrosophila melanogasterwith Specific Behavioral Defects and Cell Degeneration in the Adult

1986 • 59 citations

Specificity of gene action during central nervous system development in Drosophila melanogaster: Analysis of the lethal (1) optic ganglion reduced locus

1985 • 58 citations

Hormonal Control of Insect Metamorphosis

1981 • 56 citations

Morphology of the larval and adult brains of the monarch butterfly, Danaus plexippus plexippus, L.

1968 • 56 citations

Histology of larval eye-antennal disks and cephalic ganglia of Drosophila cultured in vitro

1966 • 55 citations

Genetic and Developmental Analysis of irreC, a Genetic Function Required for Optic Chiasm Formation in Drosophila

1990 • 54 citations

STUDIES ON THE HEXAPOD NERVOUS SYSTEM. VI. VENTRAL NERVE CORD SHORTENING; A METAMORPHIC PROCESS IN GALLERIA MELLONELLA (L.) (LEPIDOPTERA, PYRALLIDAE)

1963 • 53 citations

Developmental and ecdysteroid regulation of gene expression in the larval fat body ofDrosophila melanogaster

1986 • 50 citations

Changes occurring in the central nervous system of Pieris brassicae L. (Lepidoptera) during metamorphosis

1965 • 46 citations

A quantitative study of the growth of the central nervous system of a holometabolous insect, drosophila melanogaster

1952 • 45 citations

Projection of sensory neurons from a homeotic mutant appendage, Antennapedia, in Drosophila melanogaster

1976 • 44 citations

Genes expressed during imaginal disc morphogenesis: IMP-E1, a gene associated with epithelial cell rearrangement

1988 • 41 citations

Cytogenetic analysis of the 2B3-4 ? 2B11 region of the X chromosome of Drosophila melanogaster

1982 • 41 citations

Isolation and characterization of X-linked lethal mutants affecting differentiation of the imaginal discs in Drosophila melanogaster

1976 • 38 citations

Insect neurometamorphosis

1964 • 35 citations

Interaction of the Stubble-stubbloid locus and the Broad-complex of Drosophila melanogaster.

1988 • 35 citations

Metamorphic shortening of interganglionic connectives of Galleria mellonella (Lepidoptera) in vitro: Stimulation by ecdysone analogues

1973 • 30 citations

Cytogenetic analysis of region 2B3-4-2B11 of the X-chromosome of Drosophila melanogaster

1987 • 30 citations

Insect neurometamorphosis. IV. Effects of the brain and synthetic α‐ecdysone upon interganglionic connective shortening in Galleria mellonella (L.) (Lepidoptera)

1969 • 28 citations

Imaginal disc development in a non-pupariating lethal mutant inDrosophila melanogaster

1981 • 24 citations

Developmental Studies on the Optic Lobe of Drosophila Melanogaster Using Structural Brain Mutants

1989 • 21 citations

Trans-regulation of ecdysterone-induced protein synthesis in Drosophila melanogaster salivary glands

1988 • 19 citations

Transcription at the ecdysone-inducible locus 2B5 inDrosophila

1990 • 19 citations

Metamorphic changes of wild type and mutant Drosophila tissues induced by 20-hydroxy ecdysone in vitro

1980 • 19 citations

Modulation of a neural antigen during metamorphosis in Drosophila melanogaster

1983 • 13 citations

Differentiation and Metamorphosis of the Imaginal Optic Glomeruli in Drosophila

1956 • 13 citations

Mutation mapping of the 2B5 ecdysone locus in Drosophila melanogaster reveals a long-distance controlling element.

1989 • 11 citations

Aspects of development of imaginal discs in a non-pupariating lethal mutant in Drosophila melanogaster

1977 • 7 citations

The action of theI(1)npr-1 + locus on theDrosophila glue geneSgs-3 is cell-autonomous

1988 • 5 citations

Expression of a steroid hormone regulated gene in the cns of drosophila melanogaster

1988 • 2 citations