Molecular analysis of cytochromec Oxidase deficiency in Leigh's syndrome

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

Mitochondrial DNA Deletions in Progressive External Ophthalmoplegia and Kearns-Sayre Syndrome

1989 • 1,009 citations

Cytochrome c oxidase deficiency in leigh syndrome

1987 • 368 citations

Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease

1991 • 224 citations

Detection of "deleted" mitochondrial genomes in cytochrome-c oxidase-deficient muscle fibers of a patient with Kearns-Sayre syndrome.

1989 • 212 citations

A microdeletion in cytochrome c oxidase (COX) subunit III associated with COX deficiency and recurrent myoglobinuria

1996 • 193 citations

The Saccharomyces cerevisiae OXA1 gene is required for the correct assembly of cytochrome c oxidase and oligomycin‐sensitive ATP synthase

1996 • 144 citations

Nucleotide sequence preservation of human mitochondrial DNA.

1985 • 109 citations

Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae.

1994 • 98 citations

Nuclear DNA origin of cytochrome c oxidase deficiency in Leigh's syndrome: genetic evidence based on patient's-derived rho transformants

1995 • 83 citations

Normal variants of human mitochondrial DNA and translation products: the building of a reference data base

1991 • 82 citations

Biochemical and molecular analysis of cytochrome c oxidase deficiency in Leigh's syndrome

1991 • 73 citations

Continuous RT-PCR using AMV-RT and Taq DNA polymerase: characterization and comparison to uncoupled procedures.

1995 • 61 citations

Subunit specific monoclonal antibodies show different steady-state levels of various cytochrome-c oxidase subunits in chronic progressive external ophthalmoplegia

1996 • 57 citations

Measurement of the activity of individual respiratory chain complexes in isolated fibroblast mitochondria

1992 • 27 citations

An Antisense Oligodeoxynucleotide Approach to Investigate the Function of the Nuclear-Encoded Subunits of Human Cytochrome c Oxidase

1993 • 17 citations