Mutations in Mouse Myeloma Cells: Implications for Human Multiple Myeloma and the Production of Immunoglobulins

Immunoglobulin-producing tumors and myeloma proteins of mice.

1972 • 518 citations

PLASMA CELL MYELOMA

1963 • 320 citations

SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS

1970 • 284 citations

Cloning of mouse myeloma cells and detection of rare variants

1972 • 243 citations

Rate of Somatic Mutation in Immunoglobulin Production by Mouse Myeloma Cells

1971 • 213 citations

Rapid Viral Induction of Plasmacytomas in Pristane-Primed BALB/c Mice

1973 • 179 citations

Somatic cell hybridization of mouse myeloma cells

1976 • 146 citations

Somatic mutation and the origin of antibody diversity. Clonal variability of the immunoglobulin produced by MOPC 21 cells in culture

1973 • 144 citations

Immunocytoma o' mice an' men.

1971 • 104 citations

Mutations in Immunoglobulin-Producing Moose Myeloma Cells

1973 • 99 citations

Heavy Chain-Producing Variants of a Mouse Myeloma Cell Line

1975 • 89 citations

Clinical Classification of Plasma Cell Myeloma

1975 • 84 citations

Variants of Mouse Myeloma Cells That Produce Short Immunoglobulin Heavy Chains

1974 • 76 citations

Structural Variants of Human and Murine Immunoglobulins

1975 • 71 citations

A „LEPORE” TYPE OF HYBRID γ GLOBULIN

1969 • 67 citations

Mouse myeloma mutants blocked in the assembly, glycosylation and secretion of immunoglobulin

1976 • 66 citations

SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS

1971 • 61 citations

Mutagenesis of Mouse Myeloma Cells with ‘Melphalan’

1973 • 61 citations

Biosynthesis of immunoglobulins

1972 • 58 citations

Characterization of light chain and light chain constant region fragment mRNAs in MPC 11 mouse myeloma cells and variants

1975 • 57 citations

Synthesis and Assembly of Immunoglobulin Polypeptide Chains

2015 • 48 citations

Synthesis, assembly and secretion of gamma-globulin by mouse myeloma cells. V. Balanced and unbalanced synthesis of heavy and light chains by IgG-producing tumors and cell lines.

1973 • 43 citations

SYNTHESIS AND ASSEMBLY OF IMMUNOGLOBULINS BY MALIGNANT HUMAN PLASMACYTES

1970 • 39 citations

Synthesis, assembly, and secretion of globulin by mouse myeloma cells. IV. Assembly of IgA.

1972 • 38 citations

Gamma heavy chain disease: rapid, sustained response to cyclophosphamide and prednisone

1975 • 28 citations

THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS

1973 • 26 citations

The biosynthesis, assembly, and secretion of immunoglobulins.

1973 • 23 citations

INDEPENDENT SYNTHESIS OF LIGHT AND HEAVY CHAINS

1974 • 20 citations

Immunoglobulin Biosynthesis by the MOPC 173 Mouse Myeloma Tumor and a Variant Spleen Clone

1976 • 15 citations

Studies on the glycopeptides isolated from the urinary protein in heavy-chain disease

1968 • 13 citations

Mouse Myeloma

1975 • 12 citations

Aberrant immunoglobulin production in stable mouse myeloma tumor variants. Abstr.

1973 • 3 citations

Immune Cell Function, Viruses and Autoimmunity in New Zealand Mice

1971 • 1 citations