Translational suppression of calpain blocks long-term potentiation.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

A simple method for organotypic cultures of nervous tissue

1991 • 3,075 citations

Calcium-activated neutral protease (calpain) system: structure, function, and regulation.

1991 • 841 citations

Calpain: new perspectives in molecular diversity and physiological‐pathological involvement

1994 • 673 citations

Induction of Synaptic Potentiation in Hippocampus by Patterned Stimulation Involves Two Events

1986 • 603 citations

Current concepts in antisense drug design

1993 • 566 citations

Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

1994 • 557 citations

Dendritic spines as individual neuronal compartments for synaptic Ca2+ responses

1991 • 487 citations

Long-term potentiation as a candidate mnemonic device

1984 • 375 citations

Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain

1994 • 314 citations

Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease.

1984 • 294 citations

Independent regulation of calcium revealed by imaging dendritic spines

1991 • 272 citations

Spatial resolution of fodrin proteolysis in postischemic brain.

1993 • 270 citations

Time course of synaptic development in hippocampal organotypic cultures

1993 • 208 citations

Identification of fodrin as a major calmodulin-binding protein in postsynaptic density preparations.

1983 • 205 citations

Structural modifications associated with synaptic development in area CA1 of rat hippocampal organotypic cultures

1993 • 165 citations

NCAM-antibodies modulate induction of long-term potentiation in rat hippocampal CA1

1995 • 160 citations

Micromolar Ca2+ transients in dendritic spines of hippocampal pyramidal neurons in brain slice

1995 • 143 citations

Evidence that matrix recognition contributes to stabilization but not induction of LTP

1991 • 135 citations

An inhibitor of integrin receptors blocks long-term potentiation

1990 • 128 citations

Proteolysis of spectrin by calpain accompanies theta-burst stimulation in cultured hippocampal slices

1995 • 114 citations

Isolation and sequence analyses of cDNA clones for the large subunits of two isozymes of rabbit calcium-dependent protease.

1986 • 113 citations

Development of hippocampal long-term potentiation is reduced by recently introduced calpain inhibitors

1990 • 102 citations

Calpain inhibitors block long-term potentiation

1990 • 100 citations

Chronic administration of a thiol-proteinase inhibitor blocks long-term potentiation of synaptic responses

1988 • 93 citations

Distribution of calpain I, an enzyme associated with degenerative activity, in rat brain

1985 • 92 citations

Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices.

1995 • 79 citations

Distribution of calcium‐activated protease calpain in the rat brain

1990 • 76 citations

Induction of β-Amyloid-Containing Polypeptides in Hippocampus: Evidence for a Concomitant Loss of Synaptic Proteins and Interactions with an Excitotoxin

1994 • 72 citations

Evidence that High‐ and Low‐Affinity DL‐α‐Amino‐3‐Hydroxy‐5‐Methylisoxazole‐4‐Propionic Acid (AMPA) Binding Sites Reflect Membrane‐Dependent States of a Single Receptor

1992 • 69 citations

Translational suppression of calpain I reduces NMDA-induced spectrin proteolysis and pathophysiology in cultured hippocampal slices

1995 • 59 citations

Immunohistochemical distribution of calcium‐activated neutral proteinases and endogenous CANP inhibitor in the rabbit hippocampus

1990 • 56 citations

Calcium-activated proteolysis of intracellular domains in the cell adhesion molecules NCAM and N-cadherin

1991 • 51 citations

Effects of thiol-reagents on [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding to rat telencephalic membranes.

1988 • 50 citations

Proteolytic modification of neural cell adhesion molecule (NCAM) by the intracellular proteinase calpain

1991 • 42 citations

Effect of calpain on the composition and structure of postsynaptic densities

1995 • 41 citations

Translational suppression of a glutamate receptor subunit impairs long-term potentiation

1992 • 39 citations

Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors

1991 • 37 citations

A genetic deficiency in calpastatin and isovalerylcarnitine treatment is associated with enhanced hippocampal long‐term potentiation

1995 • 31 citations

Presence of brain spectrin in dendrites of mammalian brain: Technical factors involved in immunocytochemical detection

1988 • 25 citations

Induction and Stabilization of Long-Term Potentiation

1991 • 13 citations