Complement factor H and related proteins: an expanding family of complement-regulatory proteins?

The Regulators of Complement Activation (RCA) Gene Cluster

1989 • 442 citations

ISOLATION OF ß1F-GLOBULIN FROM HUMAN SERUM AND ITS CHARACTERIZATION AS THE FIFTH COMPONENT OF COMPLEMENT

1965 • 416 citations

Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes

1993 • 412 citations

The complete amino acid sequence of human complement factor H

1988 • 347 citations

Structure-function relationships of the complement components

1989 • 311 citations

Solution Structure of a Pair of Complement Modules by Nuclear Magnetic Resonance

1993 • 207 citations

Localization of the heparin-binding site on complement factor H.

1991 • 193 citations

Ultrastructures and interactions of complement factors H and I.

1992 • 157 citations

Human genes for three complement components that regulate the activation of C3 are tightly linked.

1985 • 155 citations

Evolution of the complement system

1991 • 127 citations

Human complement factor H: expression of an additional truncated gene product of 43 kDa in human liver

1987 • 125 citations

Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38kDa tryptic fragment of factor H

1984 • 115 citations

Solution structure of the fifth repeat of factor H: a second example of the complement control protein module

1992 • 112 citations

A study of the structure of human complement component factor H by Fourier transform infrared spectroscopy and secondary structure averaging methods

1988 • 105 citations

Secondary structure of the complement control protein module by two-dimensional proton NMR

1991 • 97 citations

Structural analysis of human complement protein H: homology with C4b binding protein, beta 2-glycoprotein I, and the Ba fragment of B2.

1986 • 85 citations

Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H

1985 • 85 citations

Molecular cloning of a human serum protein structurally related to complement factor H

1991 • 80 citations

Two major serum components antigenically related to complement factor H are different glycosylation forms of a single protein with no factor H-like complement regulatory functions.

1991 • 67 citations

Human complement factor H: An additional gene product of 43kDa isolated from human plasma shows cofactor activity for the cleavage of the third component of complement

1989 • 65 citations

Oligomeric domain structure of human complement factor H by x-ray and neutron solution scattering

1991 • 62 citations

Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes.

1992 • 56 citations

Truncated forms of human complement factor H

1989 • 53 citations

Structure of the murine complement factor H gene.

1988 • 51 citations

Genetics and Deficiencies of the Soluble Regulatory Proteins of the Complement System

1993 • 49 citations

Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.

1991 • 43 citations

A novel short consensus repeat-containing molecule is related to human complement factor H.

1993 • 41 citations

Identification and sequence analysis of four complement factor H-related transcripts in mouse liver.

1990 • 40 citations

Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.

1991 • 37 citations

Effect of trypsinization on the activity of human factor H.

1982 • 27 citations

Polymorphism and deficiency of human factor H-related proteins p39 and p37

1992 • 16 citations