Tissue-specific expression of the human α₁-antitrypsin gene is controlled by multiple cis-regulatory elements

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1983 • 659 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Nucleotide sequence analysis of the chloramphenicol resistance transposon Tn9

1979 • 494 citations

Pulmonary Emphysema and Alpha₁‐Antitrypsin Deficiency

1964 • 465 citations

Complete sequence of the cDNA for human .alpha.1-antitrypsin and the gene for the S variant

1984 • 396 citations

Sequence-specific interactions of nuclear factors with the insulin gene enhancer

1986 • 309 citations

α1-Antitrypsin deficiency detection by direct analysis of the mutation in the gene

1983 • 277 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

Histochemical staining of clonal mammalian cell lines expressingE. coli ? galactosidase indicates heterogeneous expression of the bacterial gene

1987 • 232 citations

Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts

1986 • 209 citations

Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genes.

1986 • 205 citations

A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro

1985 • 196 citations

A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene

1986 • 192 citations

Cell-specific expression of a transfected human α1-antitrypsin gene

1985 • 188 citations

Cloning and sequence of cDNA coding for alpha 1-antitrypsin.

1981 • 176 citations

A New Method for Determination of Alpha-1-antitrypsin Phenotypes Using Isoelectric Focusing on Polyacrylamide Gel Slabs

1974 • 170 citations

Identification of two factors required for transcription of the ovalbumin gene.

1986 • 166 citations

Report of nomenclature meeting for α1-antitrypsin

1980 • 151 citations

Cell-specific expression of the human complement protein Factor B gene: Evidence for the role of two distinct 5′-flanking elements

1987 • 128 citations

Identification of a second mutation in the protein-coding sequence of the Z type alpha 1-antitrypsin gene.

1986 • 127 citations

Species- and tissue-specific expression of human alpha 1-antitrypsin in transgenic mice.

1987 • 126 citations

Deletions covering the putative promoter region of early mRNAs of simian virus 40 do not abolish T-antigen expression.

1980 • 123 citations

Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice

1987 • 117 citations

The mouse immunoglobulin heavy-chain enhancer: effect on transcription in vitro and binding of proteins present in HeLa and lymphoid B cell extracts.

1986 • 114 citations

Control of transcription initiation in vitro requires binding of a transcription factor to the distal promoter of the ovalbumin gene.

1986 • 95 citations

Differential expression of the members of the discoidin I multigene family during growth and development of Dictyostelium discoideum

1982 • 89 citations

Prenatal Diagnosis of α1-Antitrypsin Deficiency by Direct Analysis of the Mutation Site in the Gene

1984 • 88 citations

Transient expression of a mouse alpha-fetoprotein minigene: deletion analyses of promoter function.

1983 • 66 citations

Multiple Regulatory Elements in the Intergenic Region Between the α-Fetoprotein and Albumin Genes

1986 • 61 citations

Relationship between an enhancer element in the human antithrombin III gene and an immunoglobulin light-chain gene enhancer

1985 • 50 citations

Control of Transcription Initiation In Vitro Requires Binding of a Transcription Factor to the Distal Promoter of the Ovalbumin Gene

1986 • 40 citations

Transient Expression of a Mouse α-Fetoprotein Minigene: Deletion Analyses of Promoter Function

1983 • 36 citations