Lethal overproduction of the Escherichia coli nucleoid protein H-NS: ultramicroscopic and molecular autopsy

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release.

1979 • 1,408 citations

Electron Microscope Study of DNA-Containing Plasms

1958 • 1,225 citations

A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli

1988 • 719 citations

Resin development for electron microscopy and an analysis of embedding at low temperature*

1982 • 714 citations

Histonelike proteins of bacteria

1987 • 699 citations

Improved plasmid vectors with a thermoinducible expression and temperature-regulated runaway replication

1983 • 362 citations

Transcriptional silencing and thermoregulation of gene expression in Escherichia coli

1990 • 315 citations

Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria

1990 • 310 citations

Histonelike proteins of bacteria.

1987 • 296 citations

Identification of a cold shock transcriptional enhancer of the Escherichia coli gene encoding nucleoid protein H-NS.

1991 • 292 citations

DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri

1990 • 243 citations

Hla, anE. coliDNA-binding protein which accumulates in stationary phase, strongly compacts DNAin vitro

1984 • 225 citations

Construction of plasmid cloning vehicles that promote gene expression from the bacteriophage lambda promoter

1979 • 220 citations

New instruments which facilitate rapid freezing at 83 K and 6 K

1982 • 211 citations

Histone-like proteins and bacterial chromosome structure.

1988 • 202 citations

The efficiency of immunolabel on Lowicryl sections compared to theoretical predictions.

1987 • 189 citations

An Escherichia coli Protein That Preferentially Binds to Sharply Curved DNA1

1990 • 187 citations

Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence?

1990 • 181 citations

The preparation of protein A-gold complexes with 3 nm and 15 nm gold particles and their use in labelling multiple antigens on ultra-thin sections

1982 • 168 citations

Proteins from the prokaryotic nucleoid: primary and quaternary structure of the 15‐kD Escherichia coli DNA binding protein H‐NS

1988 • 125 citations

CRYPTIC OPERON FOR β-GLUCOSIDE METABOLISM IN ESCHERICHIA COLI K12: GENETIC EVIDENCE FOR A REGULATORY PROTEIN

1981 • 122 citations

The osmZ (bglY) gene encodes the DNA-binding protein H-NS (H1a), a component of the Escherichia coli K12 nucleoid

1990 • 118 citations

Systematic characterization of curved DNA segments randomly cloned from Escherichia coli and their functional significance

1991 • 99 citations

Identification, cloning, nucleotide sequence and chromosomal map location of hns, the structural gene for Escherichia coli DNA-binding protein H-NS

1988 • 94 citations

Metastable regulation of type 1 piliation in Escherichia coli and isolation and characterization of a phenotypically stable mutant

1986 • 90 citations

Developments of new Lowicryl® resins for embedding biological specimens at even lower temperatures

1986 • 87 citations

Mutations altering chromosomal protein H-NS induce mini-Mu transposition.

1991 • 76 citations

Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12.

1990 • 71 citations

Sequence determinants for H1 binding on Escherichia coli lac and gal promoters

1990 • 68 citations

Mutations in bglY, the structural gene for the DNA-binding protein H1, affect expression of several Escherichia coli genes

1990 • 61 citations

Proteins from the prokaryotic nucleoid Interaction of nucleic acids with the 15 kDa Escherichia coli histone‐like protein H‐NS

1988 • 52 citations

Proteins from the Prokaryotic Nucleoid: Biochemical and 1H NMR Studies on Three Bacterial Histone-Like Proteins

1984 • 38 citations

Escherichia coli DNA-binding protein H-NS is localized in the nucleoid

1991 • 37 citations

Characterization of the structural genes for the DNA‐binding protein H‐NS in Enterobacteriaceae

1989 • 31 citations

Proteins from the Prokaryotic Nucleoid. Structural and Functional Characterization of the Escherichia coli DNA-Binding Proteins NS (HU) and H-NS

1986 • 31 citations

Considerations on the Condensation and the Degree of Compactness in Non-Eukaryotic DNA-Containing Plasmas

1986 • 28 citations

Identification of an Escherichia coli gene homologous to virR, a regulator of Shigella virulence

1989 • 28 citations

Site-directed mutagenesis of Escherichia coli translation initiation factor IF1. Identification of the amino acids involved in its ribosomal binding and recycling

1989 • 25 citations

cur-1, a mutation affecting the phenotype of sup + strains of Escherichia coli

1980 • 21 citations

Removal of background label in immunocytochemistry with the apolar lowicryls by using washed protein A–gold‐precoupled antibodies in a one‐step procedure

1989 • 19 citations