Optimization of high-performance liquid chromatography—radioimmunoassay protocols for the analyses of substance P and some of its metabolic fragments

Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli.

1983 • 374 citations

Enhancement of phagocytosis — A newly found activity of Substance P residing in its N-terminal tetrapeptide sequence

1980 • 312 citations

Post morten changes and regional distribution of substance P in the rat and mouse nervous system

1976 • 311 citations

Evidence that substance P and somatostatin transmit separate information related to pain in the spinal dorsal horn

1985 • 309 citations

PURIFICATION AND PROPERTIES OF A PROLYL ENDOPEPTIDASE FROM RABBIT BRAIN

1979 • 179 citations

Metabolism of neuropeptides. Hydrolysis of the angiotensins, bradykinin, substance P and oxytocin by pig kidney microvillar membranes

1987 • 165 citations

Liver dipeptidyl aminopeptidase IV hydrolyzes substance P

1978 • 135 citations

Cleavage of substance P to an N-terminal tetrapeptide and a C-terminal heptapeptide by a post-proline cleaving enzyme from bovine brain

1980 • 127 citations

Denaturation and the effects of temperature on hydrophobic-interaction and reversed-phase high-performance liquid chromatography of proteins

1985 • 123 citations

Characterization of substance P(1-7) and (1-8) generating enzyme in human cerebrospinal fluid

1984 • 122 citations

Spinal afferent processing

1987 • 121 citations

Measurement of Substance P Metabolites in Rat CNS

1985 • 120 citations

A fragment of substance P with specific central activity: SP(1–7)

1982 • 119 citations

3h-substance P binding to salivary gland membranes. Regulation by guanyl nucleotides and divalent cations.

1983 • 116 citations

Substance P sulfoxide: Separation from substance P by high-pressure liquid chromatography, biological and immunological activities, and chemical reduction

1980 • 104 citations

Effects of chain length and carbon load on the performance of alkyl-bonded silicas for protein separations

1983 • 67 citations

Characterization and determination of neuropeptides by high-performance liquid chromatography and radioimmunoassay

1981 • 56 citations

Active Uptake of Substance P Carboxy‐Terminal Heptapeptide (5–11) into Rat Brain and Rabbit Spinal Cord Slices

1981 • 54 citations

A Rapid and Specific Method for the High Resolution Purification and Characterization of Neuropeptides

1980 • 50 citations

Modulation of blood pressure by substance P: Opposite effects of N- and C- terminal fragments on anesthetized rats

1987 • 32 citations

Identification of substance P precursor forms in human brain tissue.

1985 • 25 citations

Characterization and partial purification of a 5,700 dalton form of substance P-like immunoreactivity from the rat hypothalamus

1984 • 18 citations

Substance P and Somatostatin Content and Transport in Vagus and Sciatic Nerves of the Streptozocin-Induced Diabetic Rat

1987 • 17 citations

Substance P and somatostatin content and transport in vagus and sciatic nerves of the streptozocin-induced diabetic rat

1987 • 10 citations

Reversed-phase ion-pair chromatography of basic, hydrophobic peptides

1986 • 7 citations

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