The Pharmacologic Basis of the Cardiovascular Toxicity of Minoxidil in the Dog

The sulfonylurea receptor

1992 • 257 citations

Transmural myocardial perfusion

1987 • 219 citations

Effect of maximal coronary vasodilation on transmural myocardial perfusion during tachycardia in the awake dog.

1977 • 204 citations

In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide.

1989 • 201 citations

Glyburide blocks the relaxation response to BRL 34915 (cromakalim), minoxidil sulfate and diazoxide in vascular smooth muscle.

1989 • 189 citations

Potassium channel openers and vascular smooth muscle relaxation

1990 • 154 citations

Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability.

1988 • 138 citations

Pharmacologic properties of minoxidil: a new hypotensive agent.

1973 • 133 citations

Potassium channel openers: pharmacological and clinical aspects

1992 • 124 citations

Cardiovascular and biological effects of K+ channel openers, a class of drugs with vasorelaxant and cardioprotective properties

1990 • 110 citations

Effects of ATP‐sensitive K⁺ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium

1991 • 91 citations

Mechanism of action and systemic and regional hemodynamics of the potassium channel activator BRL34915 and its enantiomers.

1988 • 90 citations

The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim

1990 • 87 citations

ATP‐sensitive K⁺ channels: Pharmacologic properties, regulation, and therapeutic potential

1993 • 79 citations

Vascular Pharmacology of ATP-Sensitive K<sup>+</sup> Channels: Interactions between Glyburide and K<sup>+</sup> Channel Openers

1993 • 73 citations

Pyrimidine and triazine 3-oxide sulfates: a new family of vasodilators

1983 • 73 citations

Effects of short-term and long-term theobromine administration to male dogs

1980 • 73 citations

Cardiotoxicity of Vasodilators and Positive Inotropic/Vasodilating Drugs in Dogs: An Overview

1992 • 67 citations

Pathogenesis of Cardiovascular Alterations in Dogs Treated with Minoxidil

1989 • 66 citations

Medial changes in arterial spasm induced by L-norepinephrine.

1981 • 56 citations

Acute cardiomyopathy induced by the vasodilating antihypertensive agent minoxidil

1979 • 56 citations

Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil

1993 • 55 citations

Anatomic and functional studies of the coronary circulation in the dog and pig.

1959 • 48 citations

Toxicologic studies with the hypotensive agent minoxidil

1977 • 46 citations

Pathogenesis of Arterial Lesions Induced by Dopaminergic Compounds in the Rat

1989 • 42 citations

Light and electron microscopic studies on rat arterial lesions induced by experimental arterial contraction

1979 • 40 citations

Whole Body and Regional Hemodynamic Effects of Minoxidil in the Conscious Dog

1984 • 40 citations

Comparison of the effects of the K⁺‐channel openers cromakalim and minoxidil sulphate on vascular smooth muscle

1991 • 35 citations

Potassium channels in the heart

1993 • 35 citations

Characterization of K+ channel-dependent as well as -independent components of pinacidil-induced vasodilation.

1991 • 32 citations

Cardiac morphologic alterations in acute minoxidil cardiotoxicity in miniature swine

1984 • 28 citations

Vasoconstriction and increased blood pressure in the development of accelerated vascular disease

1980 • 21 citations

Role of protein sulfation in vasodilation induced by minoxidil sulfate, a K+ channel opener.

1991 • 16 citations

Divergent effects of propranolol and furosemide pretreatment on acute cardiomyopathy induced by minoxidil in beagle dogs

1981 • 13 citations

Ionic mechanism of minoxidil sulfate-induced shortening of action potential durations in guinea pig ventricular myocytes.

1993 • 12 citations

Spontaneous Epicardial Fibrous Fronds on the Atria of Beagle Dogs

1990 • 12 citations

The Effects of X Radiation on the Canine Heart

1980 • 11 citations