Discrimination among multiple AATAAA sequences correlates with inter-species conservation of select 3'untranslated nucleotides

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

α-Thalassaemia caused by a polyadenylation signal mutation

1983 • 407 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

Nucleotide sequences of complementary deoxyribonucleic acids for the pro.alpha.1 chain of human type I procollagen. Statistical evaluation of structures that are conserved during evolution

1983 • 304 citations

Size heterogeneity in the 3′ end of dihydrofolate reductase messenger RNAs in mouse cells

1980 • 288 citations

Evolutionary history of a multigene family: An expressed human β-tubulin gene and three processed pseudogenes

1983 • 287 citations

Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAA

1983 • 278 citations

Structure of a cDNA for the pro.alpha.2 chain of human type I procollagen. Comparison with chick cDNA for pro.alpha.2(I) identifies structurally conserved features of the protein and the gene

1983 • 252 citations

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

1984 • 251 citations

Nucleotide sequence divergence and functional constraint in mRNA evolution.

1980 • 249 citations

Site-specific polyadenylation in a cell-free reaction

1984 • 223 citations

cDNA clones coding for the pro-alpha1(IV) chain of human type IV procollagen reveal an unusual homology of amino acid sequences in two halves of the carboxyl-terminal domain.

1985 • 194 citations

Isolation of cDNA and genomic clones encoding human pro-alpha 1 (III) collagen. Partial characterization of the 3' end region of the gene.

1985 • 191 citations

Multiple polyadenylation sites in a mouse α-amylase gene

1981 • 184 citations

Amino acid sequence of the non‐collagenous globular domain (NC1) of the α1 (IV) chain of basement membrane collagen as derived from complementary DNA

1985 • 164 citations

Isolation of cDNA clones specific for collagen IV and laminin from mouse teratocarcinoma cells.

1983 • 163 citations

Fine structural analysis of the human pro-alpha 1 (I) collagen gene. Promoter structure, AluI repeats, and polymorphic transcripts.

1985 • 162 citations

Analysis of the 3' end of the human pro-alpha 2(I) collagen gene. Utilization of multiple polyadenylation sites in cultured fibroblasts.

1983 • 158 citations

Highly conserved sequencim in the 3′ untranslated region of mRNAs coding for homologous proteins in distantly related species

1985 • 155 citations

Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences

1985 • 152 citations

Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene.

1982 • 146 citations

Sequence determination and analysis of the 3' region of chicken Pro-.alpha.1(I) and Pro-.alpha.2(I) collagen messenger ribonucleic acids including the carboxy-terminal propeptide sequences

1981 • 143 citations

A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.

1985 • 139 citations

Identification and characterization of the human type II collagen gene (COL2A1).

1985 • 139 citations

Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5′ and 3′ flanking homology with other RNA polymerase II transcribed genes.

1983 • 135 citations

Characterization of the chicken vimentin gene: Single copy gene producing multiple mRNAs

1983 • 133 citations

Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA.

1983 • 131 citations

Tissue-specific expression of two mRNA species transcribed from a single vimentin gene

1983 • 123 citations

Collagen genes and inherited connective tissue disease

1985 • 120 citations

Molecular cloning and carboxyl-propeptide analysis of human type III procollagen

1984 • 115 citations

Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site.

1984 • 113 citations

Requirement for the 3' flanking region of the bovine growth hormone gene for accurate polyadenylylation.

1984 • 109 citations

A highly polymorphic region 3′ to the human Type II collagen gene

1985 • 101 citations

Evolution of the human sarcomeric-actin genes: Evidence for units of selection within the 3′ untranslated regions of the mRNAs

1984 • 100 citations

Cloning and sequence of several alpha 2u-globulin cDNAs.

1981 • 96 citations

RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro.

1985 • 95 citations

DNA and chromatin structure of the human alpha 1 (I) collagen gene.

1984 • 90 citations

Isolation and partial characterization of the entire human proα I(II) collagen gene

1985 • 89 citations

Multiple forms of human dihydrofolate reductase messenger RNA

1982 • 84 citations

A conserved nucleotide sequence, coding for a segment of the C-propeptkle, is found at the same location in different collagen genes

1983 • 81 citations

Multiple 3' ends of the chicken pro α2(1) collagen gene

1983 • 78 citations

Restricted homology between human alpha 1 type IV and other procollagen chains.

1985 • 78 citations

Structure and sequence of the chicken type II procollagen gene. Characterization of the region encoding the carboxyl-terminal telopeptide and propeptide.

1984 • 76 citations

Multiple mRNA species with distinct 3′ termini are transcribed from the β2-microglobulin gene

1983 • 75 citations

Sequences on the 3′ Side of Hexanucleotide AAUAAA Affect Efficiency of Cleavage at the Polyadenylation Site

1984 • 72 citations

Complete primary structure of the human alpha 2 type V procollagen COOH-terminal propeptide.

1985 • 69 citations

Regulation of the expression of genes encoding types I, II, and III collagen during chick embryonic development.

1983 • 67 citations

Construction and partial characterization of two recombinant cDNA clones for procollagen from chicken cartilage

1982 • 55 citations

Expression of Type I and III Collagen Genes During Differentiation of Embryonic Chicken Myoblasts in Culture

1984 • 54 citations

The Structure of Collagen Genes

1983 • 44 citations

Multiple initiation and polyadenylation sites for the chicken ovomucoid transcription unit

1982 • 43 citations

RNA Sequence Containing Hexanucleotide AAUAAA Directs Efficient mRNA Polyadenylation In Vitro

1985 • 35 citations

ATTAAA As Well As Downstream Sequences Are Required for RNA 3′-End Formation in the E3 Complex Transcription Unit of Adenovirus

1985 • 35 citations

Structural features in the 3'-terminal region of polyribosome-bound rabbit globin messenger RNAs.

1986 • 20 citations