Expression of p27 and p53 in cervical squamous cell carcinoma patients treated with radiotherapy alone

p53 Mutations in Human Cancers

1991 • 8,133 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

1991 • 2,598 citations

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1993 • 2,329 citations

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas

1997 • 1,055 citations

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1997 • 929 citations

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer

1997 • 861 citations

Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer.

1997 • 428 citations

Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas.

1991 • 385 citations

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins.

1993 • 377 citations

High level expression of p27 ^kip1 and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27 ^kip1 and degree of malignancy in human breast and colorectal cancers

1997 • 364 citations

The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas.

1997 • 354 citations

Loss of cyclin-dependent kinase inhibitor p27Kip1 is a novel prognostic factor in localized human prostate adenocarcinoma.

1998 • 329 citations

Localization and expression of p27KIP1 in multistage colorectal carcinogenesis.

1998 • 201 citations

High-dose-rate remote afterloading intracavitary radiation therapy for cancer of the uterine cervix. A 20-year experience

1992 • 160 citations

Markers of radioresistance in squamous cell carcinomas of the head and neck: a clinicopathologic and immunohistochemical study.

1997 • 129 citations

Protein Expression of the Cell-Cycle Inhibitor p27Kip1 in Malignant Melanoma

1998 • 116 citations

p27KIP1 in human lung cancers: differential changes in small cell and non-small cell carcinomas.

1998 • 106 citations

Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma

1999 • 94 citations

Presence and persistence of HPV infection and p53 mutation in cancer of the cervix uteri and the vulva

1995 • 92 citations

Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer

1998 • 84 citations

Relationship between p53 status and radiosensitivity in human tumour cell lines

1996 • 77 citations

Genetic alterations of the TP53 gene, p53 protein expression and hpv infection in primary cervical carcinomas

1993 • 74 citations

p53 status of head and neck cancer: relation to biological characteristics and outcome of radiotherapy

1995 • 66 citations

Loss of p27 ^Kip1 expression independently predicts poor prognosis for patients with resectable pancreatic adenocarcinoma

1999 • 54 citations

P53 overexpression in head and neck carcinoma and radiotherapy results

1996 • 52 citations

Loss of p27Kip1 expression independently predicts poor prognosis for patients with resectable pancreatic adenocarcinoma

1999 • 42 citations

Direct sequencing of the p53 gene shows absence of mutations in endometrioid endometrial adenocarcinomas expressing p53 protein

1998 • 42 citations

Expression of p53 and p21 Proteins in Oral Squamous Cell Carcinoma: Correlation with Lymph Node Metastasis and Response to Chemoradiotherapy

1998 • 36 citations

p53 expression in carcinoma of the cervix.

1996 • 35 citations

The impact of tumour angiogenesis, p53 overexpression and proliferative activity (MIB-1) on survival in squamous cervical carcinoma

1997 • 35 citations

p53CM1 expression is not associated with prognosis in uterine cervical carcinoma

1993 • 31 citations

Altered expression of mdm-2 and its association with p53 protein status, tumor-cell-proliferation rate and prognosis in cervical neoplasia

1997 • 30 citations

Genomic deletion and p53 inactivation in cervical carcinoma

1997 • 29 citations

Mutant p53 in Patients with Invasive Cervical Cancer Stages IB to IIB

1995 • 27 citations

MIB‐1 and p53 immunocytochemistry for differentiating pilocytic astrocytomas and astrocytomas from anaplastic astrocytomas and glioblastomas in children and young adults

1998 • 26 citations

Relationship between p21/waf-1/cip-1 and apoptosis in cervical cancer during radiation therapy

1999 • 20 citations

Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma

2000 • 18 citations

Expression of human milk fat globule-1 in carcinomas of the uterine cervix treated with radiation therapy alone.

1992 • 6 citations