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Fluconazole

Data up to Jan 2025

Published1995
Citations193
References160

Total Citations Per Year

Abstract

References (160)

A Controlled Trial of Fluconazole to Prevent Fungal Infections in Patients Undergoing Bone Marrow Transplantation

1992 • 1,179 citations

A Randomized Trial Comparing Fluconazole with Amphotericin B for the Treatment of Candidemia in Patients without Neutropenia

1994 • 1,040 citations

Increase inCandida kruseiInfection among Patients with Bone Marrow Transplantation and Neutropenia Treated Prophylactically with Fluconazole

1991 • 957 citations

Resistance of Candida species to fluconazole

1995 • 890 citations

Efficacy and Safety of Fluconazole Prophylaxis for Fungal Infections after Marrow Transplantation--A Prospective, Randomized, Double-Blind Study

1995 • 820 citations

Fluconazole

1990 • 658 citations

Comparison of Amphotericin B with Fluconazole in the Treatment of Acute AIDS-Associated Cryptococcal Meningitis

1992 • 628 citations

Oral Azole Drugs as Systemic Antifungal Therapy

1994 • 583 citations

Importance of Candida Species Other than C. albicans as Pathogens in Oncology Patients

1995 • 562 citations

Pharmacokinetics and Tissue Penetration of Fluconazole in Humans

1990 • 416 citations

Fluconazole Prophylaxis of Fungal Infections in Patients with Acute Leukemia: Results of a Randomized Placebo-Controlled, Double-Blind, Multicenter Trial

1993 • 374 citations

A Controlled Trial of Fluconazole or Amphotericin B to Prevent Relapse of Cryptococcal Meningitis in Patients with the Acquired Immunodeficiency Syndrome

1992 • 354 citations

Association of Torulopsis glabrata infections with fluconazole prophylaxis in neutropenic bone marrow transplant patients

1993 • 352 citations

Fluconazole Compared with Amphotericin B plus Flucytosine for Cryptococcal Meningitis in AIDS

1990 • 345 citations

Coccidioidomycosis

1995 • 327 citations

A Randomized Trial Comparing Fluconazole with Clotrimazole Troches for the Prevention of Fungal Infections in Patients with Advanced Human Immunodeficiency Virus Infection

1995 • 324 citations

Antifungal susceptibility testing of isolates from a randomized, multicenter trial of fluconazole versus amphotericin B as treatment of nonneutropenic patients with candidemia. NIAID Mycoses Study Group and the Candidemia Study Group

1995 • 303 citations

A Placebo-Controlled Trial of Maintenance Therapy with Fluconazole after Treatment of Cryptococcal Meningitis in the Acquired Immunodeficiency Syndrome

1991 • 294 citations

Cryptococcal Meningitis and AIDS

1993 • 280 citations

Resistance of Candida albicans to Fluconazole During Treatment of Oropharyngeal Candidiasis in a Patient with AIDS: Documentation by In Vitro Susceptibility Testing and DNA Subtype Analysis

1994 • 271 citations

Emergence of azole drug resistance in Candida species from HIV-infected patients receivingprolonged fluconazole therapy for oral candidosis

1995 • 257 citations

Emergence of fluconazole-resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection

1994 • 254 citations

Clinical Pharmacokinetics of Fluconazole

1993 • 247 citations

Fluconazole susceptibilities of Candida species and distribution of species recovered from blood cultures over a 5-year period

1994 • 241 citations

Resistance of yeasts to azole-derivative antifungals

1993 • 228 citations

Fluconazole therapy for chronic disseminated candidiasis in patients with leukemia and prior amphotericin B therapy

1991 • 225 citations

Drug Interactions with Fluconazole

1990 • 224 citations

COMPARISON OF FLUCONAZOLE AND KETOCONAZOLE FOR OROPHARYNGEAL CANDIDIASIS IN AIDS

1989 • 199 citations

Hepatosplenic candidiasis: Successful treatment with fluconazole

1991 • 197 citations

Increased Gastric pH and the Bioavailability of Fluconazole and Ketoconazole

1991 • 169 citations

Influence of concomitant food intake on the oral absorption of two triazole antifungal agents, itraconazole and fluconazole

1994 • 163 citations

Correlation of in vitro fluconazole resistance of Candida isolates in relation to therapy and symptoms of individuals seropositive for human immunodeficiency virus type 1

1993 • 155 citations

Fluconazole-Resistant Candida albicans

1993 • 154 citations

Preventing Fungal Infection in Neutropenic Patients with Acute Leukemia: Fluconazole Compared with Oral Amphotericin B

1994 • 140 citations

Pharmacokinetics of fluconazole in pediatric patients

1994 • 138 citations

Fluconazole-resistant candidosis in an HIV cohort

1994 • 134 citations

Antifungal prophylaxis during remission induction therapy for acute leukemia fluconazole versus intravenous amphotericin B

1994 • 131 citations

Fluconazole Compared with Ketoconazole for the Treatment of Candida Esophagitis in AIDS

1992 • 130 citations

Comparative evaluation of alternative methods for broth dilution susceptibility testing of fluconazole against Candida albicans

1994 • 124 citations

Correlation between In Vitro and In Vivo Activity of Antifungal Agents against Candida Species

1994 • 120 citations

Candida albicans genotyping in studies with patients with AIDS developing resistance to fluconazole

1993 • 119 citations

Effect of fluconazole on the disposition of phenytoin

1991 • 119 citations

Safety and pharmacokinetics of fluconazole in children with neoplastic diseases

1992 • 119 citations

Randomized comparison of oral fluconazole versus oral polyenes for the prevention of fungal infection in patients at risk of neutropenia

1993 • 116 citations

INTERACTION BETWEEN CYCLOSPORINE AND FLUCONAZOLE IN RENAL ALLOGRAFT RECIPIENTS

1991 • 106 citations

A multicentre study of fluconazole versus oral polyenes in the prevention of fungal infection in children with hematological or oncological malignancies

1994 • 106 citations

Correlation between in vitro susceptibility ofCandida albicans and fluconazole-resistant oropharyngeal candidiasis in HIV-infected patients

1993 • 99 citations

Fluconazole-Resistant Candida albicans After Long-term Suppressive Therapy

1993 • 98 citations

Clinically Significant Mucosal Candidiasis Resistant to Fluconazole Treatment in Patients with AIDS

1994 • 98 citations

Effect of Fluconazole on Zidovudine Pharmacokinetics in Patients Infected with Human Immunodeficiency Virus

1994 • 98 citations

Controlled study of fluconazole in the prevention of fungal infections in neutropenic patients with haematological malignancies and bone marrow transplant recipients

1994 • 98 citations

FLUCONAZOLE THERAPY IN TRANSPLANT RECIPIENTS RECEIVING FK506

1994 • 96 citations

Treatment of Candida albicans fungaemia with fluconazole

1993 • 96 citations

Management of Cryptococcosis

1993 • 94 citations

Primary prophylaxis with fluconazole against systemic fungal infections in HIV-positive patients

1992 • 94 citations

Prophylaxis of Oropharyngeal Candidiasis with Fluconazole

1990 • 93 citations

Short report: the absorption of fluconazole and itraconazole under conditions of low intragastric acidity

1993 • 93 citations

Therapy for oropharyngeal candidiasis in HIV-infected patients: a randomized, prospective multicenter study of oral fluconazole versus clotrimazole troches. The Multicenter Study Group.

1993 • 90 citations

The effect of fluconazole on the steady-state pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine in humans

1993 • 84 citations

USPHS/IDSA Guidelines for the Prevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency Virus: A Summary

1996 • 84 citations

Therapy for Oropharyngeal Candidiasis in the Immunocompromised Host: A Randomized Double-Blind Study of Fluconazole vs. Ketoconazole

1990 • 82 citations

Fluconazole resistance in Candida in patients with AIDS—A therapeutic approach

1993 • 82 citations

Use of high-dose fluconazole as salvage therapy for cryptococcal meningitis in patients with AIDS

1992 • 82 citations

Combined therapy with fluconazole and flucytosine in murine cryptococcal meningitis

1991 • 80 citations

Fluconazole in the treatment of candidiasis in immunocompromised children

1991 • 79 citations

Correlation of in-vitro susceptibility test results with clinical response: a study of azole therapy in AIDS patients

1995 • 78 citations

High-Dose Fluconazole for Treatment of Cryptococcal Disease in Patients with Human Immunodeficiency Virus Infection

1994 • 75 citations

Standardized susceptibility testing of fluconazole: an international collaborative study

1992 • 75 citations

Fluconazole-Cyclosporine Interaction: A Dose-Dependent Effect?

1993 • 70 citations

Efficacies of amphotericin B-desoxycholate (Fungizone), liposomal amphotericin B (AmBisome) and fluconazole in the treatment of systemic candidosis in immunocompetent and leucopenic mice

1993 • 70 citations

Improved medium for fluconazole susceptibility testing of Candida albicans

1994 • 70 citations

Pharmacokinetic Optimisation of Oral Antifungal Therapy

1993 • 67 citations

Multisite reproducibility of colorimetric broth microdilution method for antifungal susceptibility testing of yeast isolates

1994 • 66 citations

Fluconazole prophylaxis of recurrent oral candidiasis in HIV-positive patients

1991 • 65 citations

Fluconazole-resistant Candida in AIDS patients

1993 • 65 citations

In vitro Susceptibility of 119 Yeast Isolates to Fluconazole, 5-Fluorocytosine, Amphotericin B and Ketoconazole

1991 • 65 citations

Induction of Fluconazole Metabolism by Rifampin: In Vivo Study in Humans

1991 • 64 citations

Fluconazole-Induced Symptomatic Phenytoin Toxicity

1994 • 63 citations

Effects of Preventive, Early, and Late Antifungal Chemotherapy with Fluconazole in Different Granulocytopenic Models of Experimental Disseminated Candidiasis

1990 • 63 citations

Selection of candidate quality control isolates and tentative quality control ranges for in vitro susceptibility testing of yeast isolates by National Committee for Clinical Laboratory Standards proposed standard methods

1994 • 60 citations

DNA Subtypes and Fluconazole Susceptibilities of Candida albicans Isolates from the Oral Cavities of Patients with AIDS

1995 • 60 citations

Overview of fungal infections in cancer patients.

1990 • 59 citations

Adverse Drug Reactions to Systemic Antifungals Prevention and Management

1992 • 58 citations

Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man.

1992 • 57 citations

Antifungal Prophylaxis in Bone Marrow Transplantation

1990 • 56 citations

Azoles, a48 llylamines and drug metabolism

1992 • 52 citations

Human Immunodeficiency Virus (HIV) Infection

1993 • 50 citations

Prevention of relapse of histoplasmosis with fluconazole in patients with the acquired immunodeficiency syndrome

1994 • 50 citations

Fatal acute hepatic necrosis due to fluconazole

1994 • 48 citations

Effect of Oral Antacid Administration on the Pharmacokinetics of Oral Fluconazole

1990 • 47 citations

Correlation between antifungal susceptibility testing ofCandida isolates from patients with HIV infection and clinical results after treatment with fluconazole

1994 • 46 citations

Comparison of the Efficacy of Polyenes and Triazoles against Hematogenous Candida krusei Infection in Neutropenic Mice

1993 • 44 citations

Efficacy of oral amphotericin B in AIDS patients with thrush clinically resistant to fluconazole

1994 • 43 citations

Effects of azole antifungals in vitro on host/parasite interactions relevant to candida infections

1988 • 43 citations

Histoplasmosis in the acquired immunodeficiency syndrome (AIDS): treatment with itraconazole and fluconazole.

1993 • 43 citations

Treatment of Oral Candida Mucositis Infections

1994 • 42 citations

Primary prevention of cryptococcal meningitis by fluconazole in HIV-infected patients

1995 • 42 citations

Low-Dose Fluconazole Therapy Potentiates the Hypoprothrombinemic Response of Warfarin Sodium

1993 • 41 citations

Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin a oxime derivatives and preparation of clarithromycin.

1993 • 41 citations

In vitro Susceptibility of Fungal Isolates of Clinically Important Specimens to Itraconazole, Fluconazole and Amphotericin B

1994 • 41 citations

Pharmacokinetics and bioavailability of fluconazole in patients with AIDS

1993 • 41 citations

Possible Interaction Between Warfarin and Fluconazole

1993 • 40 citations

Molecular epidemiology of Candida isolates from AIDS patients showing different fluconazole resistance profiles

1995 • 40 citations

Fluconazole once a week as secondary prophylaxis against oropharyngeal candidiasis in HIV‐infected patients: A double‐blind placebo‐controlled study

1993 • 39 citations

Comparison of the immunosuppressive activities of the antimycotic agents itraconazole, fluconazole, ketoconazole and miconazole on human T-cells

1991 • 38 citations

Fluconazole-ResistantCryptococcus NeoformansVarGattiiin an Aids Patient

1993 • 38 citations

Interaction between fluconazole and rifampicin.

1990 • 37 citations

Fluconazole Treatment of Persistent Cryptococcus neoformans Prostatic Infection in AIDS

1991 • 36 citations

Fluconazole versus ketoconazole in the treatment of oropharyngeal candidiasis in HIV-infected children

1994 • 35 citations

Fluconazole

1995 • 35 citations

USPHS/IDSA Guidelines for the Prevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency Virus: A Summary

1995 • 33 citations

Possible Potentiation of Warfarin by Fluconazole

1990 • 33 citations

Treatment of Two Cases of Cryptococcai Meningitis with Fluconazole

1988 • 32 citations

Suppression of neutrophil and lymphoproliferative responses In vitro by itraconazole but not fluconazole

1990 • 31 citations

Pharmacokinetics of Fluconazole in Serum and Cerebrospinal Fluid in a Patient with AIDS and Cryptococcal Meningitis

1990 • 31 citations

Fluconazole in the treatment of oropharyngeal candidosis in HIV‐positive patients

1990 • 31 citations

Fluconazole-lnduced Toxic Epidermal Necrolysis in a Patient with Human Immunodeficiency Virus Infection

1993 • 30 citations

Efficacy of Fluconazole in the Treatment of Upper Gastrointestinal Candidiasis in Neutropenic Patients with Cancer: Factors Influencing the Outcome

1994 • 30 citations

Fluconazole concentrations in saliva from AIDS patients with oropharyngeal candidosis refractory to treatment with fluconazole

1995 • 27 citations

In vitro effects of fluconazole (UK-49, 858) and ketoconazole on mouse lymphocyte proliferation and on Candida blastospore destruction by human polymorphonuclear leukocytes

1988 • 27 citations

Fluconazole in Children: First Experience with Prophylaxis in Chemotherapy-Induced Neutropenia in Pediatric Patients with Cancer

1993 • 24 citations

Fluconazole treatment of children with severe fungal infections not treatable with conventional agents

1994 • 24 citations

Single-dose pharmacokinetics of fluconazole in patients with liver cirrhosis

1995 • 23 citations

Evaluation of 80% inhibition standards for the determination of fluconazole minimum inhibitory concentrations in three laboratories

1994 • 23 citations

Effect of fluconazole on theophylline disposition in humans

1994 • 23 citations

Systemic amphotericin B versus fluconazole in the management of antibiotic resistant neutropenic fever — preliminary observations from a pilot, exploratory study

1995 • 23 citations

Administration of the antimycotic agents fluconazole and itraconazole to leukaemia patients: a comparative pharmacokinetic study.

1994 • 22 citations

Selection ofCandida Glabratain Pediatric Bone Marrow Transplant Recipients Receiving Fluconazole

1994 • 22 citations

Case Report: Potentiation of Warfarin by Fluconazole

1993 • 22 citations

Esophageal Candidiasis in Patients Infected With the Human Immunodeficiency Virus

1994 • 21 citations

Fluconazole and Ketoconazole in the Treatment of Oral and Esophageal Candidiasis in AIDS Patients

1992 • 21 citations

Clinical and mycological evaluation of fluconazole in the secondary prophylaxis of esophageal candidiasis in AIDS patients

1994 • 20 citations

Treatment of oropharyngeal candidiasis in HIV-infected children with oral fluconazole

1994 • 17 citations

The pharmacokinetics of fluconazole after a single intravenous dose in AIDS patients.

1994 • 16 citations

Fluconazole prophylaxis and Candida fungemia in neutropenic children with malignancies.

1993 • 16 citations

Effect of fluconazole on pharmacokinetics of 2',3'-dideoxyinosine in persons seropositive for human immunodeficiency virus

1995 • 15 citations

Cost implications of alternative treatments for aids patients with cryptococcal meningitis. Comparison of fluconazole and amphotericin b-based therapies

1991 • 15 citations

Fluconazole in the Treatment of Invasive Candidal and Cryptococcal Infections in Organ Transplant Recipients

1990 • 14 citations

Fluconazole therapy of oral candidiasis in HIV-infected patients: Results of a multicentre study

1994 • 14 citations

Cryptococcal meningitis associated with acquired immunodeficiency syndrome (AIDS) in African patients: treatment with fluconazole

1992 • 14 citations

Antifungal chemotherapy in patients with acquired immunodeficiency syndrome. British Society for Antimicrobial Chemotherapy Working Party.

1992 • 13 citations

In vitro Susceptibility Testing of <i>Candida Isolates</i> from Clinical Specimens to Four Antifungal Agents

1990 • 13 citations

Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice

1992 • 13 citations

When to use fluconazole

1995 • 12 citations

Fluconazole in patients at risk from invasive aspergillosis

1993 • 11 citations

The Use of Fluconazole Prophylaxis in Patients with Chemotherapy-Induced Neutropenia

1992 • 10 citations

Fluconazole in the treatment of fungal infections in kidney-transplanted patients.

1992 • 10 citations

[Comparative study of the therapy of Candida esophagitis in HIV-1-infected patients with fluconazole or amphotericin B and flucytosine].

1991 • 9 citations

Influence of local radiotherapy on penetration of fluconazole into human saliva

1993 • 9 citations

Comparison of Fluconazole with Amphotericin B in Treatment of Histoplasmosis in Normal and Immunosuppressed Mice

1990 • 9 citations

[Hypoglycemic coma in a patient treated with glipizide and fluconazole: a possible interaction?].

1992 • 9 citations

Comparison of the efficacy of cilofungin, fluconazole and amphotericin B in the treatment of systemicCandida albicans infection in the neutropenic mouse

1992 • 8 citations

[In vitro susceptibility to fluconazole of fungal strains freshly isolated from child patients with deep-seated mycoses].

1993 • 5 citations

Effect of fluconazole on the interactions between human neutrophils and Candida albicans

1993 • 3 citations

[Comparative sensitivity of yeasts to ketoconazole, itraconazole and fluconazole using a liquid medium standardized micromethod].

1990 • 3 citations

Fluconazole in the Treatment of Mycotic Oropharyngeal Stomatitis and Esophagitis in Neutropenic Cancer Patients

1991 • 3 citations

Comparison of fluconazole minimum inhibitory concentrations in three different formulations of RPMI-1640

1994 • 2 citations

[Oro-esophageal candidiasis resistant to fluconazole in patients with AIDS].

1993 • 2 citations

Efficacy of Prophylactic and Early Fluconazole Treatment on Systemic Candidiasis in Experimentally Neutropenic Rabbits

1993 • 1 citations

New developments in the treatment of cryptococcal disease in AIDS.

1993 • 1 citations

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