Biologic Basis of Radiation Therapy

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Radiobiology for the Radiologist.

1974 • 3,582 citations

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1996 • 2,304 citations

The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy

1955 • 2,174 citations

The hazard of accelerated tumor clonogen repopulation during radiotherapy

1988 • 1,592 citations

Radiobiology for the Radiologist

1995 • 1,349 citations

Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements.

1991 • 950 citations

Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation

1979 • 523 citations

Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves

1985 • 488 citations

The radioresponsiveness of human tumours and the initial slope ofthe cell survival curve

1984 • 472 citations

Treatment volume and tissue tolerance

1988 • 441 citations

Principles and Practice of Radiation Oncology

1992 • 356 citations

A new isoeffect curve for change in dose per fraction

1983 • 347 citations

Dose fractionation and regeneration in radiotherapy for cancer of the oral cavity and oropharynx: Tumor dose-response and repopulation

1989 • 304 citations

The Phenomenon of Reoxygenation and Its Implications for Fractionated Radiotherapy

1972 • 296 citations

Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography

1995 • 284 citations

A re-evaluation of split-course technique for squamous cell carcinoma of the head and neck

1980 • 258 citations

A Multicomponent X-ray Survival Curve for Mouse Lymphosarcoma Cells irradiated in vivo

1963 • 224 citations

Oxygenation status of a transplantable tumor during fractionated radiation therapy.

1968 • 213 citations

Predictive value of potential doubling time for radiotherapy of head and neck tumor patients: Results from the EORTC cooperative trial 22851

1992 • 187 citations

Response of cells to hyperthermia under acute and chronic hypoxic conditions.

1979 • 151 citations

Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours

1987 • 150 citations

Megavoltage irradiation of neoplasms of the nasal and paranasal cavities in 77 dogs

1993 • 132 citations

Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance

1991 • 108 citations

Nimorazole as a hypoxic radiosensitizer in the treatment of supraglottic larynx and pharynx carcinoma. First report from the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85

1991 • 94 citations

Prognostic factors associated with radiotherapy of squamous cell carcinoma of the nasal plane in cats

1995 • 88 citations

Detection of Hypoxic cells in a Murine Tumour With the Use of the Comet Assay

1992 • 82 citations

Covalent binding of a fluorinated 2-nitroimidazole to emt-6 tumors in Balb/C mice: detection by f-19 nuclear magnetic resonance at 2.35 T

1986 • 78 citations

The intrinsic radiosensitivity of cervical carcinoma: correlations with clinical data

1995 • 68 citations

Radiotherapy of soft tissue sarcomas in dogs.

1989 • 61 citations

Treatment acceleration in radiotherapy: the relative time factors and dose-response slopes for tumours and normal tissues

1992 • 57 citations

What have we learnt from hyperbaric oxygen?

1991 • 55 citations

Distribution of the hypoxia marker CCI-103F in canine tumors

1994 • 54 citations

The clinical status of Tpot as a predictor? or why no tempest in the Tpot!

1995 • 53 citations

The effect of hypoxia on acquired drug resistance and response to epidermal growth factor in chinese hamster lung fibroblasts and human breast‐cancer cells in vitro

1993 • 43 citations

Lack of complications in long-term survivors after treatment with fluosolR and oxygen as an adjuvant to radiation therapy for high-grade brain tumors

1993 • 34 citations

Local control, TCD50 and dose-time prescription habits in radiotherapy of head and neck tumours

1994 • 30 citations

ELISA quantification of CCI-103F binding in canine tumors prior to and during irradiation

1994 • 28 citations

Development of an elisa for the detection of 2-nitroimidazole hypoxia markers bound to tumor tissue

1992 • 25 citations

The effects ofO 6-benzylguanine and hypoxia on the cytotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea in nitrosourea-resistant SF-763 cells

1993 • 20 citations

Dose-time factors in head and neck data

1992 • 14 citations

A REVIEW OF TREATMENT PLANNING AND DOSE CALCULATION IN VETERINARY RADIATION ONCOLOGY

1989 • 14 citations

Aerobic Radiosensitization by SR 4233 in Rodent and Human Cells: Mechanistic and Therapeutic Implications

1991 • 14 citations

Physics and treatment planning.

1995 • 6 citations