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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

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CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

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Lactobacilli Differentially Modulate Expression of Cytokines and Maturation Surface Markers in Murine Dendritic Cells

2002 • 895 citations

Lipoteichoic Acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus Activates Immune Cells via Toll-like Receptor (TLR)-2, Lipopolysaccharide-binding Protein (LBP), and CD14, whereas TLR-4 and MD-2 Are Not Involved

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Regulation of Interleukin 12 p40 Expression through an NF-κB Half-Site

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Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures

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Role of lipoteichoic acid in infection and inflammation

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The Role of Immunoglobulin E in Allergy and Asthma

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Dendritic cells and macrophages are required for Th1 development of CD4⁺ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-_γ production is IFN-_γ-dependent

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Strain-dependent induction of cytokine profiles in the gut by orally administered Lactobacillus strains

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Stimulation of monokine production by lipoteichoic acids

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Lactic acid bacterium potently induces the production of interleukin-12 and interferon-γ by mouse splenocytes

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Streptococcal preparation OK-432 is a potent inducer of IL-12 and a T helper cell 1 dominant state.

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Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis

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Augmentation of Macrophage Phagocytic Activity by Cell-Free Extracts of Selected Lactic Acid-Producing Bacteria

1993 • 105 citations

Induction of human cytokines by bacteria used in dairy foods

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CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood mononuclear cells in an IL-12- and/or CD28-dependent manner.

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Bacterial Peptidoglycan Induces CD14-dependent Activation of Transcription Factors CREB/ATF and AP-1

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CpG Oligonucleotides Can Prophylactically Immunize Against Th2-Mediated Schistosome Egg-Induced Pathology by an IL-12-Independent Mechanism

2000 • 56 citations