The Promoter of the Human 25-Hydroxyvitamin D31α-Hydroxylase Gene Confers Positive and Negative Responsiveness to PTH, Calcitonin, and 1α,25(OH)2D3

Vitamin D

1979 • 3,814 citations

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

1997 • 1,149 citations

The Vitamin D Endocrine System: Steroid Metabolism, Hormone Receptors, and Biological Response (Calcium Binding Proteins)*

1982 • 698 citations

25-Hydroxyvitamin D ₃ 1α-Hydroxylase and Vitamin D Synthesis

1997 • 528 citations

Regulation of 25-Hydroxycholecalciferol-1-Hydroxylase Activity in Kidney by Parathyroid Hormone

1973 • 525 citations

Cloning of Human 25-Hydroxyvitamin D-1α-Hydroxylase and Mutations Causing Vitamin D-Dependent Rickets Type 1

1997 • 398 citations

Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3.

1992 • 395 citations

Inactivating Mutations in the 25-Hydroxyvitamin D₃1α-Hydroxylase Gene in Patients with Pseudovitamin D–Deficiency Rickets

1998 • 360 citations

The 25-Hydroxyvitamin D 1-Alpha-Hydroxylase Gene Maps to the Pseudovitamin D-Deficiency Rickets (PDDR) Disease Locus

1997 • 318 citations

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis.

1988 • 311 citations

Regulation of 25-Hydroxyvitamin D3-1-hydroxylase in Vivo

1974 • 253 citations

Parathyroid hormone activation of the 25-hydroxyvitamin D ₃ -1α-hydroxylase gene promoter

1998 • 250 citations

Mitochondrial Cytochrome P450

1974 • 242 citations

Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3.

1981 • 233 citations

Neonatal human foreskin keratinocytes produce 1,25-dihydroxyvitamin D3

1986 • 212 citations

Cloning and expression of rat 25-hydroxyvitamin D ₃ -1α-hydroxylase cDNA

1997 • 196 citations

Localization of 25-hydroxyvitamin D3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron.

1981 • 180 citations

Molecular Cloning of cDNA and Genomic DNA for Human 25-hydroxyvitamin D31α-hydroxylase

1997 • 180 citations

Calcitonin selectively stimulates 25-hydroxyvitamin D3-1α-hydroxylase in proximal straight tubule of rat kidney

1981 • 157 citations

Studies on Calciferol Metabolism

1974 • 141 citations

Complete Structure of the Human Gene for the Vitamin D 1α-Hydroxylase, P450c1α

1997 • 120 citations

Cloning and characterization of the rat bone sialoprotein gene promoter

1993 • 99 citations

Vitamin D receptor binding to the negative human parathyroid hormone vitamin D response element does not require the retinoid x receptor.

1996 • 94 citations

Parathyroid Hormone Modulation of 25-Hydroxyvitamin D₃Metabolism by Cultured Chick Kidney Cells Is Mimicked and Enhanced by Forskolin*

1985 • 84 citations

Intron Retention Generates a Novel Isoform of the Murine Vitamin D Receptor That Acts in a Dominant Negative Way on the Vitamin D Signaling Pathway

1996 • 82 citations

In Vitro Stimulation of 25-Hydroxycholecalciferol lα- Hydroxylation by Parathyroid Hormone in Chick Kidney Slices: Evidence for a Role for Adenosine 3′,5′- Monophosphate *

1981 • 78 citations

Subcellular location and properties of rat renal 25-hydroxyvitamin D3-1 alpha-hydroxylase.

1985 • 45 citations

Pseudo-vitamin D deficiency: absence of 25-hydroxyvitamin D 1 alpha-hydroxylase activity in human placenta decidual cells.

1995 • 44 citations

Vitamin D status regulates 25-hydroxyvitamin D3-1 alpha-hydroxylase and its responsiveness to parathyroid hormone in the chick.

1985 • 43 citations

Interactions between Intracellular Signals Involved in the Regulation of 25-Hydroxyvitamin D₃Metabolism

1989 • 43 citations

Kinetics and regulation of 25-hydroxycholecalciferol 1alpha-hydroxylase from cells isolated from human term decidua

1987 • 43 citations

Retinoic Acid Differentially Up-Regulates the Gene Expression of Retinoic Acid Receptor α and γ Isoforms in Embryo and Adult Rats

1996 • 28 citations

Cloning of Rabbit TR4 and Its Bone Cell-Specific Activity to Suppress Estrogen Receptor-Mediated Transactivation¹

1998 • 17 citations

Two Forms of Avian(Chicken) TATA-Binding Protein mRNA Generated by Alternative Polyadenylation

1997 • 9 citations