Systemic in vivo antitumor activity of interleukin-12 against both transplantable and primary tumor
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References (13)
A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
1991 • 3,493 citations
Development of T H 1 CD4 + T Cells Through IL-12 Produced by Listeria -Induced Macrophages
1993 • 3,140 citations
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.
1989 • 1,989 citations
Antitumor and antimetastatic activity of interleukin 12 against murine tumors.
1993 • 1,206 citations
Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.
1994 • 796 citations
Mechanisms of IFN-gamma induction by natural killer cell stimulatory factor (NKSF/IL-12). Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2.
1992 • 284 citations
Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation.
1993 • 103 citations
Chemically induced forestomach papillomas in transgenic mice carry mutant human c-Ha-ras transgenes.
1992 • 64 citations
Augmentation of the therapeutic efficacy of adoptive tumor immunotherapy by in vivo administration of slowly released recombinant interleukin 2
1986 • 56 citations
Superantigen-induced human CD4+ helper/killer T cell phenomenon. Selective induction of Th1 helper/killer T cells and application to tumor immunotherapy.
1995 • 26 citations
Interleukin‐12 Augments the Generation of Autologous Tumor‐reactive CD8+ Cytotoxic T Lymphocytes from Tumor‐infiltrating Lymphocytes
1995 • 23 citations
Perforin is expressed in CTL populations generated in vivo
1992 • 9 citations
Epitope mapping and functional analysis of three murine IgG1 monoclonal antibodies to human tumor necrosis factor-alpha.
1993 • 6 citations