Possible role for the glucose-fatty acid cycle in dexamethasone-induced insulin antagonism in rats

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

1963 • 5,061 citations

A RAPID PHOTOELECTRIC METHOD FOR THE DETERMINATION OF GLUCOSE IN BLOOD AND URINE

1937 • 1,305 citations

Effect of fatty acids on glucose production and utilization in man.

1983 • 1,056 citations

Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles

1964 • 729 citations

Cortisol-Induced Insulin Resistance in Man: Impaired Suppression of Glucose Production and Stimulation of Glucose Utilization due to a Postreceptor Defect of Insulin Action*

1982 • 685 citations

An easy colorimetric micromethod for routine determination of free fatty acids in plasma

1973 • 645 citations

Solid-Phase Radioimmunoassay in Antibody-Coated Tubes

1967 • 586 citations

Estimation of glycogen in small amounts of tissue

1965 • 560 citations

Glucocorticoid Inhibition of Glucose Uptake by Peripheral Tissues: Old and New Evidence, Molecular Mechanisms, and Physiological Significance

1971 • 347 citations

Insulin resistance in soleus muscle from obese Zucker rats. Involvement of several defective sites

1980 • 319 citations

Effect of long chain triglyceride infusion on glucose metabolism in man

1982 • 299 citations

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange

1978 • 293 citations

An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects.

1983 • 266 citations

Interactions of Metabolism and the Physiological Role of Insulin

1966 • 256 citations

Effect of fructose feeding on insulin secretion and insulin action in the rat

1980 • 256 citations

Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids.

1965 • 211 citations

The problem of tissue sampling from experimental animals with respect to freezing technique, anoxia, stress and narcosis

1972 • 205 citations

Insulin Hypersensitivity and Physiological Insulin Antagonists

1958 • 201 citations

Effects of Glucocorticoids on Metabolism of Adipose Tissue in Vitro

1963 • 196 citations

A Theoretical Background to the Use of Measured Concentrations of Intermediates in Study of the Control of Intermediary Metabolism

1972 • 178 citations

Studies on Rat Adipose Tissue in Vitro

1960 • 169 citations

Thyroid Hormones, Gonadal and Adrenocortical Steroids and the Function of the Islets of Langerhans

1984 • 167 citations

Physiologic Effects of Metabolic Fuels on Carbohydrate Metabolism: I. Acute Effect of Elevation of Plasma Free Fatty Acids on Hepatic Glucose Output, Peripheral Glucose Utilization, Serum Insulin, and Plasma Glucagon Levels

1967 • 158 citations

Role of Free Fatty Acids in Glucose Homeostasis

1969 • 145 citations

Carbohydrate and lipid oxidation in normal human subjects: Its influence on glucose tolerance and insulin response to glucose

1972 • 113 citations

Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men

1984 • 109 citations

1Carbohydrate metabolism in vivo: Regulation of the blood glucose level

1976 • 96 citations

Adipose tissue cellularity and lipolysis. Response to exercise and cortisol treatment.

1975 • 85 citations

Operation of the “Glucose‐Fatty Acid Cycle” during Experimental Elevations of Plasma Free Fatty Acid Levels in Man

1974 • 80 citations

The Statistical Method

1966 • 80 citations

Differential Effects of Insulin on Splanchnic and Peripheral Glucose Disposal after an Intravenous Glucose Load in Man

1982 • 74 citations

Glucose, insulin, and somatostatin infusion for the determination of insulin sensitivity in vivo

1978 • 73 citations

Stimulation of gluconeogenesis by palmitic acid in rat hepatocytes: Evidence that this effect can be dissociated from the provision of reducing equivalents

1983 • 62 citations

INFLUENCE OF FREE-FATTY-ACID METABOLISM ON GLUCOSE TOLERANCE

1964 • 59 citations

The sugar transport system in striated muscle. Effect of growth hormone, hydrocortisone and alloxan diabetes.

1962 • 58 citations

Influence of nicotinic acid on the rates of turnover and oxidation of plasma glucose in man

1973 • 49 citations

Impaired Insulin Action in Rats with Non-insulin-dependent Diabetes

1984 • 47 citations

Effect of anoxia, 2,4-dinitrophenol and salicylate on xylose transport by isolated rat soleus muscle

1977 • 47 citations

The mechanism of the potentiating effect of glucocorticoids on catecholamine-induced lipolysis

1975 • 39 citations

Effect of Free Fatty Acids and Ketone Bodies on Glucose Uptake and Oxidation in the Dog

1971 • 34 citations

Role of free fatty acids in glucose homeostasis

1969 • 34 citations

The diabetogenic action of human growth hormone: Glucose - fatty acid interrelationships

1968 • 31 citations

Effect of glucagon and glucose load on glucose kinetics, plasma FFA, and insulin in dogs treated with methylprednisolone

1973 • 28 citations

Insulin resistance of late pregnancy does not include the liver

1984 • 28 citations

The determination of reduced nicotinamide-adenine dinucleotide and metabolic intermediates in picomole amounts with bacterial luciferase

1980 • 27 citations

Impaired insulin action in rats with non-insulin-dependent diabetes

1984 • 22 citations

The effect of nicotinic acid on growth hormone-induced lipolysis and glucose intolerance.

1973 • 19 citations

Hepatocyte insulin binding and action in rats with sommatomammotrophic tumours

1983 • 18 citations

Assay of Insulin Antagonism by Serial Incubation of Paired Rat Hemidiaphragms

1966 • 17 citations

Effects of glucocorticoid administration to rats on in vitro intermediary metabolism.

1974 • 7 citations

Clinical Features of Diabetic Acidosis and Coma

1953 • 4 citations

The effect of insulin and hydrocortisone on the in vivo tissue uptake of 2-deoxyglucose in mice

1984 • 2 citations