Metabolic inactivation of bleomycin analogs by bleomycin hydrolase

Cis-Diamminedichloroplatinum, Vinblastine, and Bleomycin Combination Chemotherapy in Disseminated Testicular Cancer

1977 • 1,526 citations

A clinical review of bleomycin—a new antineoplastic agent

1973 • 860 citations

Synthetic oligonucleotide probes deduced from amino acid sequence data

1985 • 759 citations

New antibiotics, bleomycin A and B.

1966 • 721 citations

Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin.

1978 • 299 citations

The mechanism of the bleomycin-induced cleavage of DNA

1977 • 247 citations

A semiautomated microculture method for investigating growth inhibitory effects of cytotoxic compounds on exponentially growing carcinoma cells

1984 • 198 citations

Bleomycin: current Status and New Developments

1979 • 197 citations

Bleomycin: Chemical, Biochemical, and Biological Aspects

1979 • 186 citations

The Role of Strain Variation in Murine Bleomycin-lnduced Pulmonary Fibrosis^1,2

1983 • 183 citations

STUDIES ON THE MECHANISM OF ANTITUMOR EFFECT OF BLEOMYCIN ON SQUAMOUS CELL CARCINOMA

1972 • 168 citations

Metabolism and action of anti-cancer drugs

1987 • 161 citations

Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity.

1983 • 133 citations

Microbiological assay of bleomycin: Inactivation, tissue distribution, and clearance

1974 • 128 citations

ABVD chemotherapy in the treatment of Hodgkin's disease

1982 • 122 citations

Drugs Five Years Later: Bleomycin

1979 • 121 citations

Bleomycin-iron complexes. Electron spin resonance study, ligand effect, and implication for action mechanism

1980 • 119 citations

A BLEOMYCIN-INACTIVATING ENZYME IN MOUSE LIVER

1974 • 99 citations

Single-strand and double-strand deoxyribonucleic acid breaks produced by several bleomycin analogs

1981 • 73 citations

Total synthesis of bleomycin A21)

1982 • 72 citations

Total synthesis of bleomycin

1982 • 66 citations

Intracellular reduction of the cupric ion of bleomycin copper complex and transfer of the cuprous ion to a cellular protein.

1977 • 59 citations

Origin and cytotoxic properties of base propenals derived from DNA.

1985 • 50 citations

Alterations in pulmonary protective enzymes following systemic bleomycin treatment in mice

1988 • 48 citations

Purification, characterization, and amino acid composition of rabbit pulmonary bleomycin hydrolase

1987 • 45 citations

THE DISTRIBUTION OF 3H-BLEOMYCIN IN MOUSE TISSUE

1968 • 45 citations

Bleomycin hydrolase activity in pulmonary cells.

1984 • 43 citations

Cross-resistance of vinblastine- and taxol-resistant mutants of Chinese hamster ovary cells to other anticancer drugs.

1985 • 42 citations

DNA Strand Scission by Activated Bleomycin Group Antibiotics

1987 • 40 citations

Bleomycin hydrolase activity and cytotoxicity in human tumors.

1982 • 39 citations

Pulmonary fate of [3H]bleomycin A2 in mice.

1984 • 39 citations

Radioautographic studies on the intracellular distribution of bleomycin-14C in mouse tumor cells.

1974 • 38 citations

Stimulation of iron(II) bleomycin activity by phosphate-containing compounds

1985 • 34 citations

Bleomycin control of transplasma membrane redox activity and proton movement in HeLa cells

1985 • 34 citations

Properties of the initial reaction of bleomycin and several of its metal complexes with Ehrlich cells.

1986 • 34 citations

Role of DNA topology in altering the site/sequence specificity of cleavage of DNA by bleomycin and talisomycin

1983 • 30 citations

DNA damage induced by bleomycin in the presence of dibucaine is not predictive of cell growth inhibition

1985 • 29 citations

DNA methylation diminishes bleomycin-mediated strand scission

1985 • 26 citations

Purification of bleomycin hydrolase with a monoclonal antibody and its characterization

1987 • 26 citations

Separation of the protective enzyme bleomycin hydrolase from rabbit pulmonary aminopeptidases

1987 • 21 citations

Different Sensitivity to Bleomycin-Induced Pulmonary Fibrosis among Various Strains of Mice

1987 • 18 citations

Chromatographic methods for the analysis of bleomycin complex

1984 • 10 citations

Ferrous iron-mediated enhancement of DNA damage and recovery potential in bleomycin-treated human cells

1987 • 9 citations

The nature of thiol-compounds which trap cuprous ion reductively liberated from bleomycin-Cu(II) in cells.

1987 • 7 citations