PILRα, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif-bearing Protein, Recruits SHP-1 upon Tyrosine Phosphorylation and Is Paired with the Truncated Counterpart PILRβ

Improved method for high efficiency transformation of intact yeast cells

1992 • 3,258 citations

NK CELL RECEPTORS

1998 • 1,666 citations

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

1995 • 956 citations

REGULATION OF IMMUNE RESPONSES THROUGH INHIBITORY RECEPTORS

1999 • 947 citations

Crystal Structure of the Tyrosine Phosphatase SHP-2

1998 • 940 citations

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

1994 • 886 citations

Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases

1997 • 774 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

Concepts and Principles of O-Linked Glycosylation

1998 • 730 citations

Recruitment of Tyrosine Phosphatase HCP by the Killer Cell Inhibitory Receptor

1996 • 625 citations

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1993 • 578 citations

A Role in B Cell Activation for CD22 and the Protein Tyrosine Phosphatase SHP

1995 • 551 citations

Recruitment and Activation of PTP1C in Negative Regulation of Antigen Receptor Signaling by FcγRIIB1

1995 • 535 citations

LAIR-1, a Novel Inhibitory Receptor Expressed on Human Mononuclear Leukocytes

1997 • 386 citations

Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.

1996 • 362 citations

Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer

1995 • 338 citations

The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

1996 • 337 citations

Cutting Edge: Human 2B4, an Activating NK Cell Receptor, Recruits the Protein Tyrosine Phosphatase SHP-2 and the Adaptor Signaling Protein SAP

1999 • 308 citations

Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains.

1994 • 268 citations

High Expression of Inhibitory Receptor SHPS-1 and Its Association with Protein-tyrosine Phosphatase SHP-1 in Macrophages

1998 • 233 citations

Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation.

1992 • 173 citations

Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts.

1997 • 161 citations

Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1.

1996 • 142 citations

The Tyrosine Phosphatase PTP1C Associates with Vav, Grb2, and mSos1 in Hematopoietic Cells

1996 • 124 citations

Differential Roles of N- and C-Terminal Immunoreceptor Tyrosine-Based Inhibition Motifs During Inhibition of Cell Activation by Killer Cell Inhibitory Receptors

1999 • 112 citations

Use of the two hybrid system to detect the association of the protein-tyrosine-phosphatase, SHPTP2, with another SH2-containing protein, Grb7.

1996 • 98 citations

SHP-1 Associates with Both Platelet-derived Growth Factor Receptor and the p85 Subunit of Phosphatidylinositol 3-Kinase

1998 • 95 citations

Conserved Residues Amino-Terminal of Cytoplasmic Tyrosines Contribute to the SHP-1-Mediated Inhibitory Function of Killer Cell Ig-Like Receptors

1999 • 88 citations

Inhibition of the activity of protein tyrosine phosphatase 1C by its SH2 domains

1993 • 87 citations

Association of Tyrosine Phosphatases SHP-1 and SHP-2, Inositol 5-Phosphatase SHIP with gp49B1, and Chromosomal Assignment of the Gene

1998 • 78 citations

Regulation through inhibitory receptors: Lessons from natural killer cells

1997 • 76 citations

Phosphorylation and identification of a major tyrosine phosphorylation site in protein tyrosine phosphatase 1C.

1994 • 72 citations

Positive Effect of Overexpressed Protein-tyrosine Phosphatase PTP1C on Mitogen-activated Signaling in 293 Cells

1996 • 69 citations

Specificity of the SH2 Domains of SHP-1 in the Interaction with the Immunoreceptor Tyrosine-Based Inhibitory Motif-Bearing Receptor gp49B

1999 • 59 citations

The major SHP-1-binding, tyrosine-phosphorylated protein in macrophages is a member of the KIR/LIR family and an SHP-1 substrate

1998 • 40 citations

Functional Association of FcɛRIγ With Arginine632 of Paired Immunoglobulin-Like Receptor (PIR)-A3 in Murine Macrophages

1999 • 31 citations

Analysis of immunoreceptor tyrosine‐based activation motif (ITAM) binding to ZAP‐70 by surface plasmon resonance

1997 • 21 citations