T-cell depletion of allogeneic bone marrow prevents acceleration of graft-versus-host disease induced by exogenous interleukin 2

Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow.

1978 • 524 citations

DEPLETION OF T LYMPHOCYTES IN DONOR MARROW PREVENTS SIGNIFICANT GRAFT-VERSUS-HOST DISEASE IN MATCHED ALLOGENEIC LEUKAEMIC MARROW TRANSPLANT RECIPIENTS

1984 • 362 citations

Does graft-versus-host disease influence the tempo of immunologic recovery after allogeneic human marrow transplantation? An observation on 56 long-term survivors

1978 • 266 citations

In vivo interleukin 2 administration augments the generation of alloreactive cytolytic T lymphocytes and resident natural killer cells.

1983 • 245 citations

T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice

1980 • 228 citations

TRANSFER OF A FUNCTIONING HUMORAL IMMUNE SYSTEM IN TRANSPLANTATION OF T-LYMPHOCYTE-DEPLETED BONE MARROW

1986 • 159 citations

Systemic administration of recombinant interleukin 2 stimulates in vivo lymphoid cell proliferation in tissues.

1985 • 136 citations

Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers.

1982 • 121 citations

Defective interleukin 2 production in patients after bone marrow transplantation and in vitro restoration of defective T lymphocyte proliferation by highly purified interleukin 2

1984 • 97 citations

Nonspecific inhibitor released by T acceptor cells reduces the production of interleukin-2

1982 • 72 citations

Is immunological tolerance (non-responsiveness) a consequence of interleukin 2 deficit during the recognition of antigen?

1984 • 67 citations

IN VIVO ADMINISTRATION OF INTERLEUKIN-2 ENHANCES SPECIFIC ALLOIMMUNE RESPONSES

1983 • 58 citations

Immunological mechanisms of graft-versus-host disease in man.

1982 • 57 citations

Inhibiton of IL 2 production after human allogeneic bone marrow transplantation.

1983 • 53 citations

IMMUNOLOGICAL MECHANISMS OF GRAFT-VERSUS-HOST DISEASE IN MAN

1982 • 49 citations

Nonspecific inhibitor of DNA synthesis elaborated by T acceptor cells. I. Specific hapten- and I-J-driven liberation of an inhibitor of cell proliferation by Lyt-1-2+ cyclophosphamide-sensitive T acceptor cells armed with a product of Lyt-1+2+-specific suppressor cells.

1983 • 47 citations

Restoration of allograft responsiveness in B rats by interleukin 2 and/or adherent cells.

1982 • 31 citations

Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice.

1985 • 17 citations

Immunogenetics of graft-versus-host reactions to minor histocompatibility antigens

1981 • 14 citations

Human urinary bladder carcinoma cell line (T24) in long-term culture: chromosomal studies on a wild population and derived sublines.

1977 • 14 citations

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