Structure-specific model of hemoglobin cooperativity.

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

1970 • 2,874 citations

Linked Functions and Reciprocal Effects in Hemoglobin: A Second Look

1964 • 1,613 citations

Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism

1979 • 862 citations

Three-dimensional fourier synthesis of human deoxyhaemoglobin at 2·5 Å resolution: Refinement of the atomic model

1975 • 431 citations

Stereochemistry of Cooperative Effects in Hemoglobin

1972 • 282 citations

A mathematical model for structure-function relations in hemoglobin

1972 • 255 citations

Mechanism of tertiary structural change in hemoglobin.

1977 • 212 citations

Extensions of the Allosteric Model for Haemoglobin

1971 • 187 citations

Identification of residues contributing to the Bohr effect of human haemoglobin

1980 • 185 citations

Coordination complexes and catalytic properties of proteins and related substances. 104. Electrostatic effects in hemoglobin: hydrogen ion equilibriums in human deoxy- and oxyhemoglobin A

1979 • 181 citations

Oxygenation-linked subunit interactions in human hemoglobin: experimental studies on the concentration dependence of oxygenation curves

1976 • 167 citations

Studies on the Relations between Molecular and Functional Properties of Hemoglobin

1965 • 144 citations

PH dependence of the Adair constants of human hemoglobin. Nonuniform contribution of successive oxygen bindings to the alkaline Bohr effect.

1975 • 143 citations

Direct Measurement of the pK Values of an Alkaline Bohr Group in Human Hemoglobin

1973 • 127 citations

The effect of potassium chloride on the Bohr effect of human hemoglobin.

1975 • 122 citations

Proton nuclear magnetic resonance study of the quaternary structure of human hemoglobins in water

1975 • 107 citations

Alteration of functional properties associated with the change in quaternary structure in unliganded haemoglobin

1975 • 107 citations

The Three-State Model: A Minimal Allosteric Description of Homotropic and Heterotropic Effects in the Binding of Ligands to Hemoglobin

1974 • 83 citations

Coordination complexes and catalytic properties of proteins and related substances. 105. Electrostatic effects in hemoglobin: Bohr effect and ionic strength dependence of individual groups

1979 • 77 citations

Haemoglobin Hiroshima and the Mechanism of the Alkaline Bohr Effect

1971 • 74 citations

Intermediate structure of normal human haemoglobin: Methaemoglobin in the deoxy quaternary conformation

1973 • 72 citations

Analysis of the interaction of organic phosphates with hemoglobin

1976 • 72 citations

Structures of deoxy and carbonmonoxy haemoglobin Kansas in the deoxy quaternary conformation

1975 • 71 citations

Role of C-terminal histidine in the alkaline Bohr effect of human hemoglobin

1980 • 71 citations

Proton nuclear magnetic resonance investigation of structural changes associated with cooperative oxygenation of human adult hemoglobin

1979 • 70 citations

A proton nuclear magnetic resonance investigation of histidyl residues in human normal adult hemoglobin

1982 • 64 citations

The Binding of a Spin-labeled Triphosphate to Hemoglobin

1972 • 55 citations

Hemoglobin cochin-port-royal: Consequences of the replacement of the β chain C-terminal by an arginine

1975 • 48 citations

Self-association of hemoglobin β ^SH chains is linked to oxygenation

1978 • 44 citations

Structural and functional studies of hemoglobin Barcelona (α2β2 94 Asp (FG1) → his)

1982 • 44 citations

Electrostatic contributions to the energetics of dimer-tetramer assembly in human hemoglobin: pH dependence and effect of specifically bound chloride ions

1981 • 42 citations

Proton nuclear magnetic resonance and biochemical studies of oxygenation of human adult hemoglobin in deuterium oxide

1979 • 41 citations

Anaysis of cooperativity in hemoglobin. Valency hybrids, oxidation, and methemoglobin replacement reactions

1975 • 40 citations

Response of the Bohr group salt bridges to ligation of the T state of haemoglobin Kansas

1978 • 33 citations

The contribution of histidine (HC3) (146 beta) to the R state Bohr effect of human hemoglobin.

1982 • 32 citations

Cross correlation of titrating histidines in oxy‐ and deoxyhaemoglobin; an NMR study

1976 • 26 citations

An Estimation of the First Binding Constant of O2 to Human Hemoglobin A

1978 • 26 citations

Thermodynamic analysis of human hemoglobins in terms of the Perutz mechanism: extensions of the Szabo Karplus model to include subunit assembly

1982 • 22 citations

Sequence of oxygen binding by hemoglobin

1978 • 13 citations

Preference of oxygenation between α and β subunits of haemoglobin

1983 • 11 citations