The Good, the Bad, and the Cell Type-Specific Roles of Hypoxia Inducible Factor-1α in Neurons and Astrocytes

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O ₂ -Regulated Prolyl Hydroxylation

2001 • 5,255 citations

‘Green mice’ as a source of ubiquitous green cells

1997 • 2,586 citations

A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF

2001 • 2,481 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

2000 • 1,769 citations

Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse

2002 • 1,309 citations

New roles for astrocytes: Redefining the functional architecture of the brain

2003 • 1,283 citations

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

2007 • 1,160 citations

Astrocyte glutamate transport: Review of properties, regulation, and physiological functions

2000 • 1,157 citations

Astrocytes and Brain Injury

2003 • 878 citations

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

2000 • 784 citations

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

2000 • 754 citations

Neuron-Specific Inactivation of the Hypoxia Inducible Factor 1 Increases Brain Injury in a Mouse Model of Transient Focal Cerebral Ischemia

2007 • 336 citations

Brain-Specific Knock-Out of Hypoxia-Inducible Factor-1α Reduces Rather Than Increases Hypoxic-Ischemic Damage

2005 • 236 citations

The Transcriptional Activator Hypoxia Inducible Factor 2 (HIF-2/EPAS-1) Regulates the Oxygen-Dependent Expression of Erythropoietin in Cortical Astrocytes

2006 • 230 citations

Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

1999 • 186 citations

Hypoxia-Inducible Factor-1α Mediates Hypoxia-Induced Delayed Neuronal Death That Involves p53

1999 • 153 citations

Astrocyte glutamate uptake during chemical hypoxia in vitro

1992 • 116 citations

Prosurvival and Prodeath Effects of Hypoxia-inducible Factor-1α Stabilization in a Murine Hippocampal Cell Line

2004 • 106 citations

Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor

1999 • 61 citations

In Cultured Astrocytes, p53 and MDM2 Do Not Alter Hypoxia-inducible Factor-1α Function Regardless of the Presence of DNA Damage

2007 • 23 citations