Blockade of Vascular Endothelial Cell Growth Factor Receptor Signaling Is Sufficient to Completely Prevent Retinal Neovascularization

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

1994 • 3,652 citations

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

1996 • 3,649 citations

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

1995 • 1,608 citations

Oxygen-induced retinopathy in the mouse.

1994 • 1,564 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

1995 • 1,280 citations

Increased Vascular Endothelial Growth Factor Levels in the Vitreous of Eyes With Proliferative Diabetic Retinopathy

1994 • 1,269 citations

Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization.

1995 • 1,021 citations

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

1995 • 990 citations

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

2000 • 848 citations

Inhibition of Vascular Endothelial Growth Factor Prevents Retinal Ischemia—Associated Iris Neovascularization in a Nonhuman Primate

1996 • 638 citations

Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis on a primate model

1994 • 584 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

1995 • 466 citations

The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal diseases

1948 • 456 citations

Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases.

1995 • 425 citations

Essential Role of Growth Hormone in Ischemia-Induced Retinal Neovascularization

1997 • 394 citations

Transgenic Mice with Increased Expression of Vascular Endothelial Growth Factor in the Retina: A New Model of Intraretinal and Subretinal Neovascularization.

1998 • 367 citations

Detection of Vascular Endothelial Growth Factor Messenger RNA and Vascular Endothelial Growth Factor-like Activity in Proliferative Diabetic Retinopathy

1994 • 367 citations

Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy.

1996 • 357 citations

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor–type integrins inhibits retinal neovascularization

1996 • 336 citations

Vascular Endothelial Growth Factor/Vascular Permeability Factor is Temporally and Spatially Correlated with Ocular Angiogenesis In a Primate Model

1995 • 290 citations

RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class.

1995 • 270 citations

Variable oxygen exposure causes preretinal neovascularization in the newborn rat.

1993 • 209 citations

Blindness Caused by Diabetic Retinopathy

1974 • 194 citations

Dramatic Inhibition of Retinal and Choroidal Neovascularization by Oral Administration of a Kinase Inhibitor

1999 • 171 citations

Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors.

1998 • 161 citations

Inhibition of platelet‐derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferation

1997 • 125 citations

Antagonists of integrin alpha v beta 3 inhibit retinal neovascularization in a murine model.

1996 • 118 citations