Monoclonal antibody to Lyt 2 antigen blocks H–2I- and H–2K- specific mouse cytotoxic T cells

Mouse lymphocytes with and without surface immunoglobulin: Preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin

1977 • 568 citations

Regulation of Cellular and Humoral Immune Responses by T-cell Subclasses

1977 • 368 citations

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera

1979 • 208 citations

Preparation and use of Ly antisera

1975 • 182 citations

Mouse alloantibodies capable of blocking cytotoxic T-cell function. I. Relationship between the antigen reactive with blocking antibodies and the Lyt-2 locus.

1979 • 146 citations

Murine T Lymphocyte Clones with Distinct Immunological Functions

1981 • 133 citations

GENETIC CORRELATION OF A MOUSE LIGHT CHAIN VARIABLE REGION MARKER WITH A THYMOCYTE SURFACE ANTIGEN

1974 • 130 citations

Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.

1975 • 121 citations

Blocking effect of lyt-2 antibodies on T cell functions.

1980 • 114 citations

The Effect of T Cell Growth Factor on the Generation of Cytolytic T Cells

1978 • 113 citations

The Lyt phenotype of a long‐term allospecific T cell line. Both helper and killer activities to IA are mediated by Ly‐1 cells

1981 • 93 citations

T-T cell interactions during in vitro cytotoxic T lymphocyte (CTL) responses. II. Helper factor from activated Lyt 1+ T cells is rate limiting i) in T cell responses to nonimmunogenic alloantigen, ii) in thymocyte responses to allogeneic stimulator cells, and III) recruits allo- or H-2-restricted CTL precursors from the Lyt 123+ T subset.

1980 • 88 citations

Helper Cells Activated by Allogeneic H-2K or H-2D Differences Have a Ly Phenotype Distinct from Those Responsive to I Differences

1979 • 76 citations

Histocompatibility antigens controlled by the I region of the murine H-2 complex. II. K/D region compatibility is not required for I-region cell-mediated lymphocytotoxicity.

1977 • 68 citations

Studies on the induction and expression of T cell-mediated immunity. X. Inhibition by Lyt 2,3 antisera of cytotoxic T lymphocyte-mediated antigen-specific and -nonspecific cytotoxicity: evidence for the blocking of the binding between T lymphocytes and target cells and not the post-binding cytolytic steps.

1980 • 63 citations

The differentiation of cytotoxic T cells in vitro. II. Amplifying factor(s) produced in primary mixed lymphocyte cultures against K/D stimuli require the presence of Lyt 2+ cells but not Lyt 1+ cells.

1980 • 60 citations

Lyt phenotypes of primary cytotoxic T cells generated across the A and E region of the H‐2 complex

1981 • 46 citations

INBRED AND GENETICALLY DEFINED STRAINS OF LABORATORY ANIMALS. PART 2

1980 • 46 citations

Continuous cytotoxic T cell lines reactive against murine plasmacytoma tumor-associated antigens.

1981 • 26 citations

Fine specificity mapping of two allospecific T cell lines: recognition of private specificities in the H‐2 IA subregion

1981 • 23 citations

Cytotoxic T lymphocytes generated across an I‐A^b mutant difference are directed against a molecule bearing Ia antigens

1981 • 19 citations

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