Alveolar Cell Stretching in the Presence of Fibrous Particles Induces Interleukin-8 Responses

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS

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The Mechanics of Aerosols

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Signal transduction from the extracellular matrix.

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Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function

1995 • 900 citations

Receptors; models for binding, trafficking and signaling

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Bronchoalveolar lavage

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Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

1990 • 678 citations

Interleukin-8 (IL-8): The Major Neutrophil Chemotactic Factor in the Lung

1991 • 550 citations

Asbestos-Related Diseases

1989 • 513 citations

Molecular biology of the cell (2nd edn)

1989 • 424 citations

Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals

1995 • 375 citations

Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions

1998 • 368 citations

Role of integrins in cellular responses to mechanical stress and adhesion

1997 • 335 citations

Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts.

1998 • 330 citations

Surfactant displaces particles toward the epithelium in airways and alveoli

1990 • 279 citations

The pathogenicity of long versus short fibre samples of amosite asbestos administered to rats by inhalation and intraperitoneal injection.

1986 • 257 citations

Cellular and Molecular Basis of the Asbestos-related Diseases

1991 • 251 citations

Chrysotile asbestos inhalation in rats: deposition pattern and reaction of alveolar epithelium and pulmonary macrophages.

1981 • 234 citations

Generation of superoxide (O2-.) from alveolar macrophages exposed to asbestiform and nonfibrous particles.

1987 • 228 citations

Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species.

1996 • 160 citations

Device for the application of a dynamic biaxially uniform and isotropic strain to a flexible cell culture membrane

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Surface charge and asbestos toxicity

1977 • 142 citations

Retinoid differentiation therapy in promyelocytic leukemia

1996 • 130 citations

Inflammation generating potential of long and short fibre amosite asbestos samples.

1989 • 124 citations

Evidence supporting a role for active oxygen species in asbestos-induced toxicity and lung disease.

1989 • 111 citations

Toward a kinetic theory of connective tissue micromechanics

1993 • 107 citations

Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers.

1994 • 100 citations

Surface charge and hemolytic activity of asbestos

1977 • 99 citations

Asbestos stimulates IL-8 production from human lung epithelial cells.

1994 • 90 citations

Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin alpha v beta 5.

1995 • 85 citations

Lung Epithelial Cell (A549) Interaction with Unopsonized Environmental Particulates: Quantitation of Particle-Specific Binding and IL-8 Production

1996 • 83 citations

Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbits.

1992 • 72 citations

Induction of DNA strand breaks in cultured rat embryo cells by crocidolite asbestos as assessed by nick translation.

1989 • 64 citations

The adsorption of biological macromolecules by mineral dusts

1978 • 47 citations

Detection of 8-oxo-2'-deoxyguanosine, a marker of oxidative DNA damage, in culture medium from human mesothelial cells exposed to crocidolite asbestos

1996 • 43 citations

Serum promotes asbestos-induced injury to human pulmonary epithelial cells.

1990 • 32 citations

Asbestos fibre length-dependent detachment injury to alveolar epithelial cells in vitro: role of a fibronectin-binding receptor.

1993 • 28 citations

Heat Shock-Induced Shedding of Cell Surface Integrins in A549 Human Lung Tumor Cells in Culture

1994 • 22 citations

Selective adsorption of serum proteins by chrysotile and crocidolite

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Biophysical Modulation of Cell and Tissue Structure and Function

1995 • 11 citations

DEPOSITION EFFICIENCY OF INHALED FIBERS IN THE HAMSTER LUNG

1997 • 3 citations