Approach to the use of antigen non-specific immunosuppression in systemic lupus erythematosus and other rheumatic autoimmune diseases

Therapy of Lupus Nephritis

1986 • 1,163 citations

Textbook of Rheumatology.

1988 • 593 citations

The Mechanism of Immunological Paralysis

1968 • 401 citations

Systemic autoimmune disease arises from polyclonal B cell activation.

1987 • 314 citations

Increased Spontaneous Polyclonal Activation of B Lymphocytes in Mice with Spontaneous Autoimmune Disease

1978 • 305 citations

The lupus autoantigens and the pathogenesis of systemic lupus erythematosus

1986 • 259 citations

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis.

1987 • 236 citations

Pathogenesis of rheumatoid arthritis

1986 • 205 citations

Increased spontaneous activity of antibody‐forming cells in the peripheral blood of patients with active sle

1977 • 197 citations

The Cellular and Genetic Basis of Murine Lupus

1981 • 195 citations

Abnormally elevated frequency of Epstein-Barr virus-infected B cells in the blood of patients with rheumatoid arthritis.

1984 • 194 citations

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype.

1983 • 188 citations

Demonstration of Activation of B Lymphocytes in New Zealand Black Mice at Birth by an Immunoradiometric Assay for Murine IgM

1977 • 183 citations

Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus

1980 • 178 citations

Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice.

1980 • 166 citations

Rheumatoid Arthritis: Evolving Concepts of Pathogenesis and Treatment

1984 • 152 citations

Changes in immunoglobulin class and subclass of anti-DNA antibodies with increasing age in N/ZBW F1 hybrid mice.

1976 • 146 citations

Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model.

1987 • 145 citations

Immunological regulation of spontaneous antibodies to DNA and RNA. II. Sequential switch from IgM to IgG in NZB/NZW F1 mice.

1977 • 145 citations

Qualitative characteristics of anti‐DNA antibodies in lupus nephritis

1974 • 124 citations

Synthesis of IgM by Cells of NZB and SWR Mice and Their Crosses

1979 • 122 citations

B cell dependence on and response to accessory signals in murine lupus strains.

1983 • 108 citations

Therapeutic studies in NZB/W MICE

1975 • 103 citations

Abnormal Polyclonal B Cell Activation in NZB/NZW F1 Mice

1977 • 90 citations

The treatment of lupus nephritis

1986 • 78 citations

T cell abnormalities in NZB mice occur independently of autoantibody production.

1981 • 77 citations

Strategies of Immune Regulation

1980 • 73 citations

Management of systemic lupus erythematosus.

1982 • 65 citations

Acquisition and maturation of expressed B cell repertoires in normal and autoimmune mice.

1988 • 57 citations

Role of the Sm antigen in the generation of anti-Sm autoantibodies in the SLE-prone MRL mouse.

1986 • 48 citations

Proliferation of anti-DNA-producing NZB B cells in a non-autoimmune environment.

1986 • 46 citations

Evidence for abnormalities in separate lymphocyte populations in NZB mice.

1980 • 42 citations

Selective production of autoantibodies in graft-vs-host-induced and spontaneous murine lupus. Predominant reactivity with histone regions accessible in chromatin.

1988 • 40 citations

Regulation of the class of immune response induced by antigen

1983 • 36 citations

The regulatory role of NZB T lymphocytes in the production of anti-DNA antibodies in vitro.

1986 • 35 citations

Differences in the Age-Dependent Release of a Low Molecular Weight Suppressor (LMWS) and Stimulators by Normal and NZB/W Lymphoid Organs

1976 • 34 citations

Similar in vivo expansion of B cells from normal DBA/2 and autoimmune NZB mice in xid recipients.

1987 • 28 citations

Natural murine autoantibodies and conventional antibodies exhibit similar degrees of antigenic cross-reactivity.

1988 • 25 citations

Increased Multiclonal Antibody-Forming Cell Activity in the Peripheral Blood of Patients with SLE

1981 • 25 citations

The role of splenic colony-forming units in autoimmune disease

1988 • 19 citations

Determinants of B cell hyperactivity in murine lupus.

1988 • 17 citations

Evidence that Lyb-5 is a differentiation antigen in normal and xid mice.

1986 • 16 citations

Studies of immune abnormalities in systemic lupus erythematosus.

1982 • 16 citations

Flow cytometry and cytoadherence studies of sera from children with juvenile rheumatoid arthritis and normal controls

1981 • 14 citations

Genetic and molecular genetic studies of murine and human lupus.

1987 • 14 citations

Transfer of anti-DNA-producing B cells from NZB to unmanipulated xid recipients: Effects of age, sex, and environment

1987 • 8 citations