Serotonergic innervation of the cerebral vasculature: relevance to migraine and ischaemia

Pharmacology of Cerebral Ischemia

1989 • 675 citations

Basic mechanisms of headache

1989 • 215 citations

Central serotonergic nerves project to the pial vessels of the brain

1983 • 190 citations

5‐HT₁‐like receptors mediate 5‐hydroxytryptamine‐induced contraction of human isolated basilar artery

1989 • 169 citations

Pharmacological analysis of 5-hydroxytryptamine receptors in isolated intracranial and extracranial vessels of cat and man.

1978 • 156 citations

(S)‐Emopamil, a novel calcium channel blocker and serotonin S ₂ antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat

1988 • 139 citations

Vascular Neuroeffector Mechanisms

1984 • 125 citations

Serotonin as a neurotransmitter in cerebral arteries

1982 • 123 citations

Effects of 5‐hydrooxytryptamine on pial arteriolar calibre in anaesthetized cats

1977 • 104 citations

IMMUNOHISTOCHEMICAL DEMONSTRATION OF SEROTONIN IN NERVES SUPPLYING HUMAN CEREBRAL AND MESENTERIC BLOOD-VESSELS

1983 • 82 citations

Contractile 5‐HT₁ receptors in human isolated pial arterioles: correlation with 5‐HT_1D binding sites

1991 • 78 citations

Cerebral circulatory and metabolic effects of 5‐hydroxytryptamine in anesthetized baboons.

1977 • 78 citations

Serotonin as an alternative transmitter in sympathetic nerves of large cerebral arteries of the rabbit.

1987 • 78 citations

Heterogeneous vasomotor responses of anatomically distinct feline cerebral arteries

1988 • 72 citations

Median raphe, but not dorsal raphe, application of the 5-HT1A agonist 8-OH-DPAT stimulates rat motor activity

1989 • 67 citations

Evidence for mediation by 5-HT2 receptors of 5-hydroxytryptamine-induced contraction of canine basilar artery

1983 • 66 citations

Region-selective inhibition of male rat sexual behavior and motor performance by localized forebrain 5-HT injections: a comparison with effects produced by 8-OH-DPAT

1991 • 63 citations

Indoleaminergic mechanisms in brain vessels; Localization, concentration, uptake and in vitro responses of 5‐hydroxytryptamine

1984 • 61 citations

Neurochemical studies on the existence, origin and characteristics of the serotonergic innervation of small pial vessels

1985 • 55 citations

Canine basilar artery contractions mediated by 5-hydroxytryptamine1A receptors.

1986 • 51 citations

The Effects of Serotonin on Local Cerebral Blood Flow

1983 • 47 citations

Analysis of the 5-hydroxytryptamine induced contraction of the human basilar arterial strip compared with the rat aortic strip in vitro

1982 • 46 citations

Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. II. Effects of electrical stimulation of the rostral raphé nuclei

1988 • 46 citations

Effects of Electrical Stimulation of the Dorsal Raphe Nucleus on Local Cerebral Blood Flow in the Rat

1989 • 45 citations

Effect of Serotonin and its Antagonist Ketanserin on Pial Vessels

1985 • 45 citations

Serotonergic innervation of cat cerebral arteries

1985 • 42 citations

Differential patterns of local cerebral glucose utilization in response to 5-hydroxytryptamine, agonists

1988 • 42 citations

Serotonin uptake into cerebrovascular nerve fibers of rat, visualization by immunohistochemistry, disappearance following sympathectomy, and release during electrical stimulation

1989 • 39 citations

Concentrations of Putative Neurovascular Transmitters in Major Cerebral Arteries and Small Pial Vessels of Various Species

1987 • 39 citations

Effect of stimulation of nucleus raphe dorsalis on carotid blood flow. II. The cat

1985 • 38 citations

Can the vascular and neurogenic theories of migraine finally be reconciled?

1989 • 38 citations

5-Hydroxytryptamine demonstrated immunohistochemically in rat cerebrovascular nerves largely represents 5-hydroxytryptamine uptake into sympathetic nerve fibres

1989 • 37 citations

Pharmacological properties of the receptor(s) involved in the 5-hydroxytryptamine-induced contraction of the feline middle cerebral artery.

1989 • 37 citations

Local Cerebral Glucose Utilisation Following Indoleamine‐ and Piperazine‐Containing 5‐Hydroxytryptamine Agonists

1986 • 36 citations

Effect of the 5-HT1A receptor agonist ipsapirone on the local cerebral glucose utilization of the rat hippocampus

1987 • 33 citations

Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. I. Effects of electrolytic or neurotoxic lesions of the dorsal and/or median raphé nucleus

1988 • 33 citations

Effect of the Serotonin Antagonist Ketanserin on the Hemodynamic and Morphological Consequences of Thrombotic Infarction

1989 • 32 citations

Evidence for Differing Origins of the Serotonergic Innervation of Major Cerebral Arteries and Small Pial Vessels in the Rat

1991 • 32 citations

Evidence for a possible role for serotonergic systems in the control of cerebral blood flow

1990 • 29 citations

Cerebral Blood Flow in Migraine and Cluster Headache

1978 • 29 citations

Heterogeneity in the response to vasoconstrictors of isolated dog proximal and distal middle cerebral arteries

1984 • 28 citations

Serotonin-synthesizing nerve fibers in rat and cat cerebral arteries and arterioles: Immunohistochemistry of tryptophan-5-hydroxylase

1990 • 27 citations

Dual Action of Serotonin on Pial Arterioles <i>in situ</i> and the Effect of Propranolol on the Response

1977 • 27 citations

Migraine: a research field matured for the basic neurosciences

1991 • 25 citations

Differential Effects of Electrical Stimulation of the Dorsal Raphe Nucleus and of Cervical Sympathectomy on Serotonin and Noradrenaline Concentrations in Major Cerebral Arteries and Pial Vessels in the Rat

1990 • 21 citations

Regional differences in the response to nicotine in isolated canine arteries

1976 • 19 citations

Kinetic Studies on Uptake of Serotonin and Noradrenaline into Pial Arteries of Rats

1990 • 18 citations

Serotonin Depression of Local Cerebral Glucose Utilisation after Monoamine Oxidase Inhibition

1985 • 17 citations

Serotonin Receptors in Vascular Smooth Muscle

1988 • 13 citations

Chronic effects of the selective serotoninergic neurotoxin, methylenedioxyamphetamine, upon cerebral function

1990 • 12 citations

Methiothepin reduces glucose utilization in forebrain regions of awake rats

1987 • 9 citations