The mitochondrial ADP/ATP carrier: Structural, physiological and pathological aspects

CLUSTAL V: improved software for multiple sequence alignment

1992 • 2,421 citations

Metal chelate affinity chromatography, a new approach to protein fractionation

1975 • 2,050 citations

New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues

1987 • 1,107 citations

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

1997 • 554 citations

Molecular and physiological aspects of adenine nucleotide trasport in mitochondria

1976 • 373 citations

Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation.

1992 • 316 citations

Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase

1982 • 310 citations

Immunological analysis of auto-antibodies against the adenine nucleotide translocator in dilated cardiomyopathy

1985 • 214 citations

The mitochondrial transport protein superfamily

1993 • 213 citations

A third ADP/ATP translocator gene in yeast.

1990 • 205 citations

Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane.

1986 • 202 citations

Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated.

1987 • 198 citations

Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria

1965 • 191 citations

Molecular weight and hydrodynamic parameters of the adenosine 5'-diphosphate-adenosine 5'-triphosphate carrier in Triton X-100

1980 • 177 citations

Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.

1988 • 173 citations

BIOCHEMICAL STRUCTURE OF MITOCHONDRIA

1955 • 159 citations

THE EFFECT OF ATRACTYLATE AND OLIGOMYCIN ON THE BEHAVIOUR OF MITOCHONDRIA TOWARDS ADENINE NUCLEOTIDES

1965 • 148 citations

Endogenous ADP of mitochondria, an early phosphate acceptor of oxidative phosphorylation as disclosed by kinetic studies with C14 labelled ADP and ATP and with atractyloside

1965 • 136 citations

Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes

1990 • 123 citations

Mapping of facioscapulohumeral muscular dystrophy gene to chromosome 4q35-qter by multipoint linkage analysis and in situ hybridization

1991 • 118 citations

Site-directed Mutagenesis of the Yeast Mitochondrial ADP/ATP Translocator

1993 • 113 citations

Mitochondrial DNA expression in mitochondrial myopathies and coordinated expression of nuclear genes involved in ATP production

1993 • 109 citations

Chemical, immunological, enzymatic, and genetic approaches to studying the arrangement of the peptide chain of the ADP/ATP carrier in the mitochondrial membrane

1993 • 108 citations

BIOCHEMICAL STRUCTURE OF MITOCHONDRIA

1955 • 102 citations

Atractyloside as inhibitor of energy-transfer reactions in liver mitochondria

1962 • 90 citations

ADP/ATP translocator is essential only for anaerobic growth of yeast Saccharomyces cerevisiae

1991 • 88 citations

Action of potassium atractylate on oxidative phosphorylation in mitochondria and in submitochondrial particles

1962 • 85 citations

Transcript levels for nuclear‐encoded mammalian mitochondrial respiratory‐chain components are regulated by thyroid hormone in an uncoordinated fashion

1992 • 78 citations

Coordinate expression of nuclear and mitochondrial genes involved in energy production in carcinoma and oncocytoma

1996 • 76 citations

OXBOX, a positive transcriptional element of the heart-skeletal muscle ADP/ATP translocator gene

1990 • 76 citations

A human pseudoautosomal gene, ADP/ATP translocase, escapes X–inactivation whereas a homologue on Xq is subject to X–inactivation

1993 • 76 citations

Antibody evidence for different conformational states of ADP, ATP translocator protein isolated from mitochondria.

1976 • 75 citations

Selection of the nuclear gene for the mitochondrial adenine nucleotide translocator by genetic complementation of the op1 mutation in yeast.

1982 • 73 citations

Orientation of the N-terminal region of the membrane-bound ADP/ATP carrier protein explored by antipeptide antibodies and an arginine-specific endoprotease. Evidence that the accessibility of the N-terminal residues depends on the conformational state of the carrier

1989 • 72 citations

Éxchange entre adenine-nucleotides extra- et intramitochondriaux

1965 • 70 citations

Probing the Role of Positive Residues in the ADP/ATP Carrier from Yeast. The Effect of Six Arginine Mutations on Transport and the Four ATP versus ADP Exchange Modes

1996 • 69 citations

INTRAMITOCHONDRIAL NUCLEOTIDES

1958 • 69 citations

Probing the Role of Positive Residues in the ADP/ATP Carrier from Yeast. The Effect of Six Arginine Mutations on Oxidative Phosphorylation and AAC Expression

1996 • 68 citations

Differential regulation of expression of the multiple ADP/ATP translocase genes in human cells.

1991 • 67 citations

Gummiferin, an inhibitor of the adenine‐nucleotide translocation. Study of its binding properties to mitochondria

1971 • 61 citations

The site of action of atractyloside

1964 • 61 citations

Principles of Carrier Catalysis Elucidated by Comparing Two Similar Membrane Translocators from Mitochondria, the ADP/ATP Carrier and the Uncoupling Protein^a

1985 • 61 citations

Topography of the membrane-bound ADP/ATP carrier assessed by enzymic proteolysis

1992 • 61 citations

Deficiency of the Adenine Nucleotide Translocator in Muscle of a Patient with Myopathy and Lactic Acidosis: A New Mitochondrial Defect

1993 • 53 citations

Small angle neutron scattering of the mitochondrial ADPATP carrier protein in detergent

1982 • 53 citations

Structure-function relationships of the ADP/ATP carrier

1994 • 52 citations

The multiple ADP/ATP translocase genes are differentially expressed during human muscle development.

1992 • 51 citations

A Human Pseudoautosomal Gene Encodes the ANT3 ADP/ATP Translocase and Escapes X-Inactivation

1993 • 51 citations

Localization of the N-ethylmaleimide reactive cysteine in the beef heart mitochondrial ADP/ATP carrier protein

1984 • 43 citations

Function-based Mapping of the Yeast Mitochondrial ADP/ATP Translocator by Selection for Second Site Revertants

1993 • 37 citations

Substrate-site interactions in the membrane-bound adenine-nucleotide carrier as disclosed by ADP and ATP analogs

1984 • 34 citations

Biochemical Characterisation of the Isolated Anc2 Adenine Nucleotide Carrier from Saccharomyces cerevisiae Mitochondria

1993 • 31 citations

Substrate-induced modifications of the intrinsic fluorescence of the isolated adenine nucleotide carrier protein: demonstration of distinct conformational states

1985 • 27 citations

Substrate-induced fluorescence changes of the isolated ADP/ATP carrier protein in solution

1981 • 26 citations

The human skeletal muscle adenine nucleotide translocator gene maps to chromosome 4q35 in the region of the facioscapulohumeral muscular dystrophy locus

1993 • 26 citations

Conformational Changes of the Yeast Mitochondrial Adenosine Diphosphate/Adenosine Triphosphate Carrier Studied through Its Intrinsic Fluorescence. 1. Tryptophanyl Residues of the Carrier Can Be Mutated without Impairing Protein Activity

1996 • 24 citations

Use of 3'-O-naphthoyladenosine 5'-diphosphate to probe distinct conformational states of the membrane-bound ADP/ATP carrier

1983 • 24 citations

Exploration of the nucleotide binding sites of the isolated ADP/ATP carrier protein from beef heart mitochondria. 1. Probing of the nucleotide sites by naphthoyl-ATP, a fluorescent nontransportable analog of ATP

1982 • 23 citations

Genetic Mapping of Human Heart-Skeletal Muscle Adenine Nucleotide Translocator and Its Relationship to the Facioscapulohumeral Muscular Dystrophy Locus

1993 • 21 citations

Chemical radiolabeling of carboxyatractyloside by [¹⁴C]acetic anhydride

1980 • 21 citations

Importance of mitochondrial transmembrane processes in human mitochondriopathies

1996 • 20 citations

Iodination of peripheral mitochondrial membrane proteins in correlation to the functional state of the carrier

1976 • 20 citations

Fluorometric Titration of the Mitochondrial ADP/ATP Carrier Protein in Muscle Homogenate with Atractyloside Derivatives

1996 • 20 citations

The yeast ADP/ATP carrier. Mutagenesis and second-site revertants

1996 • 19 citations

Conformational Changes of the Yeast Mitochondrial Adenosine Diphosphate/Adenosine Triphosphate Carrier Studied through Its Intrinsic Fluorescence. 2. Assignment of Tryptophanyl Residues of the Carrier to the Responses to Specific Ligands

1996 • 18 citations

Synthesis and properties of fluorescent derivatives of atractyloside as potential probes of the mitochondrial ADP/ATP carrier protein

1983 • 16 citations

Exploration of the nucleotide binding sites of the isolated ADP/ATP carrier protein from beef heart mitochondria. 2. Probing of the nucleotide sites by formycin triphosphate, a fluorescent transportable analog of ATP

1982 • 16 citations

Localization of immunoreactive regions in the beef heart adenine nucleotide carrier using rabbit antisera against the carboxyatractyloside-liganded and the sodium dodecyl sulfate denatured carrier forms

1986 • 15 citations

Adenine nucleotide translocator deficiency in muscle: Potential therapeutic value of vitamin E

1993 • 9 citations

Molecular Aspects Of Structure-Function Relationships In Mitochondrial Adenine Nucleotide Carrier

2018 • 2 citations