Isolation of interleukin 2-induced immediate-early genes.

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Current protocols in molecular biology

1988 • 4,543 citations

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

The Interleukin-2 T-Cell System: A New Cell Growth Model

1984 • 935 citations

T‐Cell Growth Factor

1980 • 917 citations

Cloning of the γ Chain of the Human IL-2 Receptor

1992 • 835 citations

Expression cloning of the murine erythropoietin receptor

1989 • 776 citations

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1991 • 660 citations

Haemopoietic receptors and helical cytokines

1990 • 642 citations

Transient expression of interleukin 2 receptors. Consequences for T cell growth.

1983 • 613 citations

DNA damage-inducible transcripts in mammalian cells.

1988 • 613 citations

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

1991 • 597 citations

Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

1985 • 589 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase.

1988 • 552 citations

A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

1992 • 508 citations

A new cytokine receptor superfamily

1990 • 506 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

1990 • 476 citations

Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor

1990 • 468 citations

T cell antigen receptor activation pathways: The tyrosine kinase connection

1991 • 442 citations

Functional consequences of interleukin 2 receptor expression on resting human lymphocytes. Identification of a novel natural killer cell subset with high affinity receptors.

1990 • 436 citations

A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization

1989 • 370 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains.

1991 • 297 citations

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.

1991 • 268 citations

T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates

1989 • 258 citations

Interleukin-2 Induction of T-Cell G ₁ Progression and c- myb Expression

1986 • 248 citations

T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck.

1991 • 218 citations

The immediate-early growth response in regenerating liver and insulin-stimulated H-35 cells: comparison with serum-stimulated 3T3 cells and identification of 41 novel immediate-early genes.

1991 • 216 citations

Erythropoietin receptor and interleukin-2 receptor β chain: A new receptor family

1989 • 208 citations

Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cells

1988 • 183 citations

T‐CELL GROWTH FACTOR‐MEDIATED T‐CELL PROLIFERATION*

1979 • 168 citations

Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line.

1991 • 165 citations

Complexity of the Early Genetic Response to Growth Factors in Mouse Fibroblasts

1988 • 159 citations

Complexity of the primary genetic response to mitogenic activation of human T cells.

1989 • 149 citations

Regulation of pim and myb mRNA accumulation by interleukin 2 and interleukin 3 in murine hematopoietic cell lines.

1988 • 141 citations

Interleukin-2 induces proliferation of T lymphocyte mutants lacking protein kinase C

1988 • 137 citations

Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines.

1991 • 133 citations

Cell Growth and Differentiation

2004 • 124 citations

Kinases and phosphatases in T-cell activation

1989 • 118 citations

Interleukin 2-induced lymphocyte proliferation is independent of increases in cytosolic-free calcium concentrations.

1985 • 113 citations

Interleukin 2 does not induce phosphatidylinositol hydrolysis in activated T cells.

1986 • 102 citations

Localized cytosolic domains of the erythropoietin receptor regulate growth signaling and down-modulate responsiveness to granulocyte-macrophage colony-stimulating factor.

1991 • 97 citations

Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants.

1990 • 97 citations

Regulation of T cell autocrine growth. T4+ cells become refractory to interleukin 2.

1986 • 94 citations

Molecular cloning of a novel human cdc2/CDC28-like protein kinase

1991 • 87 citations

Interleukin-2-Triggered Raf-1 Expression, Phosphorylation, and Associated Kinase Activity Increase through G₁ and S in CD3-Stimulated Primary Human T Cells

1991 • 82 citations

cDNA cloning and characterization of interleukin 2-induced genes in a cloned T helper lymphocyte.

1990 • 77 citations

The Cytoplasmic Region of the Erythropoietin Receptor Contains Nonoverlapping Positive and Negative Growth-Regulatory Domains

1991 • 76 citations

Protein tyrosine phosphorylation associated with activation of the interleukin 2 receptor.

1990 • 75 citations

The Immediate-Early Growth Response in Regenerating Liver and Insulin-Stimulated H-35 Cells: Comparison with Serum-Stimulated 3T3 Cells and Identification of 41 Novel Immediate-Early Genes

1991 • 59 citations

Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae.

1984 • 57 citations

Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants.

1990 • 55 citations

Selective isolation of newly synthesized mammalian mRNA after in vivo labeling with 4-thiouridine or 6-thioguanosine

1988 • 50 citations

Complexity of the Primary Genetic Response to Mitogenic Activation of Human T Cells

1989 • 50 citations

Stimulation of the antigen and interleukin-2 receptors on T lymphocytes activates distinct tyrosine protein kinases.

1990 • 42 citations

The cDNA sequence and gene analysis of the human pim oncogene

1987 • 41 citations

Identification of the human pim-1 gene product as a 33-kilodalton cytoplasmic protein with tyrosine kinase activity.

1988 • 35 citations

Identification of the Human pim-1 Gene Product as a 33-Kilodalton Cytoplasmic Protein with Tyrosine Kinase Activity

1988 • 10 citations