Phorbol ester induction of leukemic cell differentiation is a membrane-mediated process.

Cytochemical Identification of Monocytes and Granulocytes

1971 • 2,735 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Handbook of Experimental Pharmacology.

1971 • 1,547 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

1979 • 532 citations

Induction of terminal differentiation in human promyelocytic leukemia cells by tumor-promoting agents.

1979 • 513 citations

Specific binding of phorbol ester tumor promoters

1980 • 364 citations

Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion

1979 • 337 citations

Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters

1980 • 274 citations

Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.

1975 • 220 citations

Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.

1981 • 144 citations

Differentiation of human leukemias in response to 12-0- tetradecanoylphorbol-13-acetate in vitro

1980 • 121 citations

Proliferation, differentiation, and cytogenetics of chronic leukemic B lymphocytes cultured with mitomycin-treated normal cells

1981 • 117 citations

Identification of receptors for phorbol ester tumor promoters in intact mammalian cells and of an inhibitor of receptor binding in biologic fluids.

1981 • 114 citations

Rapid stimulation of phospholipid metabolism in bovine lymphocytes by tumor-promoting phorbol esters.

1978 • 113 citations

Characterization of specific binding of [3H]phorbol 12,13-dibutyrate and [3H]phorbol 12-myristate 13-acetate to mouse brain.

1980 • 107 citations

Specific receptors for phorbol esters in lymphoid cell populations: role in enhanced production of T-cell growth factor.

1981 • 81 citations

Stimulation of choline incorporation in cell cultures by phorbol derivatives and its correlation with their irritant and tumor-promoting activity.

1979 • 78 citations

Tetradecanoyl-phorbol acetate stimulates phosphatidylcholine biosynthesis in hela cells by an increase in the rate of the reaction catalyzed by CTP: Phosphocholine cytidylyltransferase

1980 • 70 citations

Arachidonic acid and prostaglandin E2 release and enhanced cell proliferation induced by the phorbol ester TPA in a murine epidermal cell line

1981 • 64 citations

Alterations in lipid metabolism induced by 12-O-tetradecanoylphorbol-13-acetate in differentiating human myeloid leukemia cells.

1980 • 52 citations

Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester

1981 • 46 citations

Biosynthesis of membrane-derived oligosaccharides: a periplasmic phosphoglyceroltransferase.

1981 • 43 citations

α-Tocopherol inhibits 12−O-tetradecanoylphorbol-13-acetate-stimulated deacylation of cellular lipids, prostaglandin production, and changes in cell morphology of madin-darby canine kidney cells

1980 • 35 citations

Decreased synthesis of high-molecular-weight glycopeptides in human promyelocytic leukemic cells (HL-60) during phorbol ester-induced macrophage differentiation.

1982 • 35 citations

Tumor promoters enhance myeloid and erythroid colony formation by normal mouse hemopoietic cells.

1980 • 33 citations

Inhibition of sterol and phospholipid synthesis in HL-60 promyelocytic leukemia cells by inducers of myeloid differentiation.

1981 • 32 citations

Modification of normal human myelopoiesis by 12-0 tetradecanoylphorbol- 13-acetate (TPA)

1981 • 31 citations