Reduction of pulmonary toxicity

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

A clinical review of bleomycin—a new antineoplastic agent

1973 • 860 citations

Druginduced pulmonary disease. Part 1 : Cytotoxic drugs

1986 • 544 citations

Bleomycin-induced pulmonary fibrosis in the rat: inhibition by indomethacin.

1979 • 306 citations

Raynaud's Phenomenon: A Common Toxicity After Combination Chemotherapy for Testicular Cancer

1981 • 293 citations

Bleomycin, an Antitumor Antibiotic

1972 • 293 citations

The pulmonary toxicity of antineoplastic agents.

1982 • 237 citations

Bleomycin, a review.

1976 • 210 citations

Bleomycin: Chemical, Biochemical, and Biological Aspects

1979 • 186 citations

Severe Bleomycin-Induced Pneumonitis

1984 • 145 citations

Mechanism of bleomycin action: studies

1981 • 145 citations

Pulmonary toxicity of antineoplastic agents

1983 • 133 citations

Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity.

1983 • 133 citations

Bleomycin Treatment of the Tumors of Penis and Scrotum

1969 • 130 citations

Activity and toxicity of bleomycin.

1967 • 130 citations

Continuous intravenous bleomycin (NSC-125066) therapy with vinblastine (NSC-49842) in stage III testicular neoplasia.

1975 • 127 citations

Bleomycin Hypersensitivity Pneumonitis

1978 • 126 citations

Clinical pharmacologic and therapeutic studies of bleomycin given by continuous infusion

1977 • 125 citations

Drug-induced pulmonary disease. Part 2: Noncytotoxic drugs.

1986 • 116 citations

Improved therapeutic index of bleomycin when administered by continuous infusion in mice.

1978 • 114 citations

Phase II evaluation of bleomycin.A Southwest Oncology Group study

1976 • 113 citations

Bleomycin-induced pulmonary fibrosis in the rat. Prevention with an inhibitor of collagen synthesis.

1980 • 103 citations

Role of single-breath carbon monoxide-diffusing capacity in monitoring the pulmonary effects of bleomycin in germ cell tumor patients.

1979 • 97 citations

Raynaud's phenomenon of the lung

1984 • 86 citations

Pulmonary toxicity after radiation and bleomycin: A review

1979 • 86 citations

Pulmonary Toxicity of Antineoplastic Drugs

1981 • 85 citations

Effects of intratracheal administration of bleomycin on GSH-shuttle enzymes, catalase, lipid peroxidation, and collagen content in the lungs of hamsters

1983 • 85 citations

Pulmonary toxicity of antitumor agents

1983 • 83 citations

Ultrastructural study of bleomycin‐induced pulmonary changes in mice

1978 • 65 citations

Potentiation of bleomycin-induced lung injury by exposure to 70% oxygen. Morphologic assessment.

1982 • 64 citations

Bleomycin-induced pulmonary fibrosis: Correlation of biochemical, physiological, and histological changes

1981 • 61 citations

Prospective study of the pulmonary toxicity of continuously infused bleomycin.

1981 • 59 citations

Continuous intravenous bleomycin (NSC-125066) therapy with vinblastine (NSC-49842) in stage III testicular neoplasia.

1975 • 55 citations

The Effect of Deferoxamine on Bleomycin-induced Lung Fibrosis in the Hamster

1985 • 53 citations

Alteration of bleomycin cytotoxicity by glutathione depletion or elevation

1984 • 50 citations

Evaluation of antifibrotic drugs in bleomycin-induced pulmonary fibrosis in hamsters.

1980 • 49 citations

Modification of oxygen toxicity after lung injury by bleomycin in hamsters.

1982 • 48 citations

Redox cycling of Fe(III)-bleomycin by NADPH-cytochrome P-450 reductase

1981 • 45 citations

The response of human lymphoma cells in vitro to bleomycin and 1,3-bis(2-chloroethyl)-1-nitrosourea.

1972 • 45 citations

Potentiation of Bleomycin-induced Lung Injury by Exposure to 70% Oxygen

2015 • 44 citations

Pulmonary toxicity of bleomycin analogs

1980 • 44 citations

Antitumour activity and plasma kinetics of bleomycin by continuous and intermittent administration

1980 • 40 citations

Deferoxamine injection does not affect bleomycin-induced lung fibrosis in rats.

1985 • 32 citations

Inhibition of collagen accumulation by glucocorticoids in rat lung after intratracheal bleomycin instillation.

1982 • 31 citations

Inhibition of bleomycin lung toxicity by N-acetyl cysteine in the rat

1985 • 30 citations

Inhibition of bleomycin-induced pulmonary fibrosis by lipopolysaccharide.

1984 • 30 citations

Relative pulmonary toxicity and antitumor effects of two new bleomycin analogs, pepleomycin and tallysomycin A.

1980 • 28 citations

Die Bleomycin-Lunge

1977 • 26 citations

Effects of dimethyl sulfoxide (DMSO) on bleomycin-induced pulmonary fibrosis

1985 • 26 citations

Liblomycin, a new analogue of bleomycin

1987 • 25 citations

Potentiation of bleomycin cytotoxicity by membrane-interacting drugs and increased calcium ions

1982 • 22 citations

Pulmonary toxicity of antineoplastic drugs

1981 • 18 citations

Phase I evaluation of peplomycin with special reference to pulmonary toxicity

1983 • 11 citations

Raynaud-Syndrom nach kombinierter zytostatischer Behandlung von Patienten mit malignen Hodentumoren^*

1982 • 10 citations

Transient bleomycin-induced thrombocytopenia. A clinical study

1978 • 9 citations

Minor role of lipid peroxidation in acute bleomycin toxicity in rats

1982 • 9 citations

Bleomycin-Induced Pulmonary Fibrosis

2018 • 8 citations

Metal Complex of Bleomycin and Its Implication for the Mechanism of Bleomycin Action

1979 • 7 citations

Inhibitory effect of D-penicillamine on the fibrosis caused by bleomycin treatment in rat carrageenin granuloma.

1977 • 5 citations

Peplomycin

1984 • 5 citations

Continuous Infusion Versus Intermittent Bolus Injection of Bleomycin in a Human Embryonal Testicular Cancer Xenograft

1984 • 4 citations

Neue Bleomycin-Derivate

1982 • 1 citations