Monocytes and Macrophages: Functions and Diseases

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

1973 • 2,955 citations

Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity

1972 • 966 citations

In Vitro Bactericidal Capacity of Human Polymorphonuclear Leukocytes: Diminished Activity in Chronic Granulomatous Disease of Childhood *

1967 • 932 citations

THE INFLUENCE OF IMMUNOLOGICALLY COMMITTED LYMPHOID CELLS ON MACROPHAGE ACTIVITY IN VIVO

1969 • 932 citations

Myeloperoxidase-Halide-Hydrogen Peroxide Antibacterial System

1968 • 840 citations

Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection

1969 • 697 citations

Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage.

1974 • 654 citations

A METHOD OF STUDYING LEUKOCYTIC FUNCTIONS IN VIVO

1955 • 619 citations

Phagocytic activation of a luminol-dependent chemiluminescence in rabbit alveolar and peritoneal macrophages

1976 • 572 citations

ALTERATIONS OF MACROPHAGE FUNCTIONS BY MEDIATORS FROM LYMPHOCYTES

1971 • 507 citations

METABOLIC PATTERNS IN THREE TYPES OF PHAGOCYTIZING CELLS

1963 • 500 citations

THE PARTICULATE HYDROLASES OF MACROPHAGES

1963 • 422 citations

Direct Evidence for a Bone Marrow Origin of the Alveolar Macrophage in Man

1976 • 381 citations

Abnormal Bactericidal, Metabolic, and Lysosomal Functions of Chediak-Higashi Syndrome Leukocytes

1972 • 372 citations

Superoxide production by phagocytic leukocytes.

1975 • 257 citations

Human alveolar macrophages: comparison of phagocytic ability, glucose utilization, and ultrastructure in smokers and nonsmokers

1970 • 241 citations

Antibacterial activity of cationic proteins from human granulocytes.

1975 • 220 citations

THE ENHANCEMENT OF MACROPHAGE BACTERIOSTASIS BY PRODUCTS OF ACTIVATED LYMPHOCYTES

1973 • 215 citations

Receptors for Immunoglobulin and Complement on Human Alveolar Macrophages

1975 • 208 citations

Factors Influencing Killing of Cryptococcus neoformans by Human Leukocytes In Vitro

1972 • 204 citations

Pulmonary Alveolar Macrophage DEFENDER AGAINST BACTERIAL INFECTION OF THE LUNG

1974 • 202 citations

Cationic Proteins of Polymorphonuclear Leukocyte Lysosomes II. Composition, Properties, and Mechanism of Antibacterial Action

1966 • 191 citations

The fungicidal mechanisms of human monocytes. I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms.

1975 • 191 citations

The human alveolar macrophage: isolation, cultivation in vitro, and studies of morphologic and functional characteristics

1971 • 191 citations

The Depressant Effect of Cigarette Smoke on the in Vitro Antibacterial Activity of Alveolar Macrophages

1967 • 188 citations

Defective Lung Macrophages in Pulmonary Alveolar Proteinosis

1976 • 184 citations

CELLULAR IMMUNITY IN VITRO

1971 • 182 citations

A review and reevaluation of the histiocytic disorders

1973 • 173 citations

An Inhibitor of Macrophage Chemotaxis Produced by Neoplasms

1976 • 165 citations

EFFECT OF NORMAL AND ACTIVATED HUMAN MACROPHAGES ON TOXOPLASMA GONDII

1974 • 156 citations

Growth of Pulmonary Alveolar Macrophages in vitro

1973 • 155 citations

Occult pulmonary haemorrhage in leukaemia.

1975 • 150 citations

THE ORIGIN OF ALVEOLAR MACROPHAGES IN MOUSE RADIATION CHIMERAS

1972 • 145 citations

Cationic Proteins of Polymorphonuclear Leukocyte Lysosomes I. Resolution of Antibacterial and Enzymatic Activities

1966 • 142 citations

Hydrogen peroxide utilization in myeloperoxidase-deficient leukocytes: a possible microbicidal control mechanism

1971 • 140 citations

Defective Bactericidal Activity in Myeloperoxidase-deficient Human Neutrophils

1969 • 139 citations

A comparison of the metabolic response to phagocytosis in human granulocytes and monocytes.

1976 • 134 citations

Nonoxidative Fungicidal Mechanisms of Mammalian Granulocytes: Demonstration of Components with Candidacidal Activity in Human, Rabbit, and Guinea Pig Leukocytes

1975 • 132 citations

Specificity of opsonic antibodies to enhance phagocytosis of Pseudomonas aeruginosa by human alveolar macrophages.

1975 • 128 citations

Monocyte function in man.

1977 • 127 citations

Enhancement of macrophage bactericidal capacity by antigenically stimulated immune lymphocytes

1972 • 118 citations

Functional Aspects of a Second Mechanism of Candidacidal Activity by Human Neutrophils

1972 • 116 citations

Cytoplasmic inclusions in pulmonary macrophages of cigarette smokers.

1975 • 112 citations

Proliferative Capacity of Human Alveolar Macrophage

1974 • 109 citations

Catalase-dependent peroxidative metabolism in the alveolar macrophage during phagocytosis

1970 • 106 citations

Regulation of Granulopoiesis

1974 • 103 citations

IODINATING ABILITY OF VARIOUS LEUKOCYTES AND THEIR BACTERICIDAL ACTIVITY

1973 • 97 citations

Defective Mononuclear Leukocyte Chemotaxis: A Previously Unrecognized Immune Dysfunction

1973 • 97 citations

The ultrastructure of alveolar macrophages from human cigarette smokers and nonsmokers.

1971 • 96 citations

Alveolar macrophages. Structural and functional differences between nonsmokers and smokers of marijuana and tobacco.

1971 • 95 citations

DEPRESSED MONOCYTE CHEMOTAXIS DURING ACUTE INFLUENZA INFECTION

1975 • 94 citations

Immunocompetent cells from the lower respiratory tract of normal human lungs.

1975 • 93 citations

Comparison of proteolytic enzyme activity in pulmonary alveolar macrophages and blood leukocytes in smokers and nonsmokers.

1975 • 93 citations

Function of H ₂ O ₂ , Myeloperoxidase, and Hexose Monophosphate Shunt Enzymes in Phagocytizing Cells from Different Species

1970 • 91 citations

The Pulmonary Macrophage in Acute Leukemia

1974 • 87 citations

Defective Bactericidal Activity of Monocytes in Fatal Granulomatous Disease

1969 • 86 citations

Alpha-1-antitrypsin content in the serum, alveolar macrophages, and alveolar lavage fluid of smoking and nonsmoking normal subjects.

1975 • 84 citations

Defective Monocyte Function in Patients With Genitourinary Carcinoma 2

1975 • 82 citations

Isolation and Properties of Phagocytic Vesicles II. ALVEOLAR MACROPHAGES

1972 • 77 citations

Defective mononuclear leukocyte chemotaxis in the Chediak-Higashi syndrome of humans, mink, and cattle

1975 • 77 citations

Cell division of alveolar macrophages in rat lung following exposure to NO2.

1973 • 71 citations

FURTHER STUDIES ON PREPARATION AND PROPERTIES OF PHAGOCYTIN

1960 • 70 citations

The biochemical activities of rabbit alveolar macrophages during phagocytosis

1965 • 70 citations

Defective Mononuclear Phagocyte Function in Patients with Myelomonocytic Leukemia and in Some Patients with Lymphoma

1973 • 69 citations

A defect in circulating mononuclear phagocytes in chronicgranulomatous disease of childhood.

1968 • 67 citations

Differences between Monocyte-Derived and Tissue Macrophages

1976 • 65 citations

CATIONIC PROTEINS AND ANTIBACTERIAL PROPERTIES OF INFECTED TISSUES AND LEUKOCYTES.

1963 • 63 citations

Clonal growth of hamster free alveolar cells in soft agar.

1975 • 61 citations

Chemotaxis of Macrophages

1976 • 59 citations

Effect of Bacillus Calmette-Guérin on the Levels of Acid Phosphatase, Lysozyme and Cathepsin in Rabbit Alveolar Macrophages

1965 • 56 citations

Defense Mechanisms of the Lungs

1975 • 53 citations

Glutathione-dependent peroxidative metabolism in the alveolar macrophage

1971 • 51 citations

Occult pulmonary hemorrhage in anticoagulated patients.

1975 • 49 citations

A new white cell test which measures individual phagocyte function in a mixed leukocyte population. I. A neutrophil defect in acute myelocytic leukemia.

1973 • 46 citations

Bactericidal mechanisms in rabbit alveolar macrophages: evidence against peroxidase and hydrogen peroxide bactericidal mechanisms

1976 • 44 citations

Peroxidase activity of alveolar and peritoneal macrophages.

1973 • 43 citations

Subversion of host defense mechanisms by murine tumors. II. Counter-influence of concomitant antitumor immunity.

1976 • 42 citations

Peroxidase activity of alveolar macrophages.

1976 • 39 citations

Pathogenesis of one variant of sea-blue histiocytosis.

1975 • 39 citations

Antimicrobial Activity of Gatalase at Acid pH

1969 • 38 citations

Peroxidase Mediated Antimicrobial Activities of Alveolar Macrophage Granules

1973 • 36 citations

Pinocytosis by Human Alveolar Macrophages COMPARISON OF SMOKERS AND NONSMOKERS

1974 • 34 citations

Mononuclear Phagocyte Proliferation, Maturation and Function

1975 • 29 citations

Marrow origin of canine alveolar macrophages.

1975 • 27 citations

Role of Macrophages in T Cell–B Cell Collaboration in Antibody Production

1976 • 26 citations

Metabolic Event Involved in the Bactericidal Activity of Normal Mouse Macrophages

1971 • 24 citations

Cellular and Molecular Aspects of Chemotaxis of Macrophages and Monocytes

1976 • 24 citations

Macrophage esterase: Identification, purification and properties of a chymotrypsin-like esterase from lung that hydrolyses and transfers nonpolar amino acid esters

1975 • 24 citations

Altered Phospholipid Metabolism in Escherichia coli Accompanying Killing by Disrupted Granulocytes

1975 • 16 citations

Function of the alveolar macrophage in immunity.

1972 • 14 citations

Action de la fumée de tabac sur le macrophage alvéolaire. Quelques données récentes

1975 • 4 citations