H+/dipeptide absorption across the human intestinal epithelium is controlled indirectly via a functional Na+/H+ exchanger

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger

1998 • 839 citations

Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney

1976 • 665 citations

Human Intestinal H+/Peptide Cotransporter

1995 • 495 citations

cAMP-mediated inhibition of the epithelial brush border Na ⁺ /H ⁺ exchanger, NHE3, requires an associated regulatory protein

1997 • 426 citations

Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

1995 • 413 citations

A C-terminal motif found in the β ₂ -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na ⁺ /H ⁺ exchanger regulatory factor family of PDZ proteins

1998 • 406 citations

The Expanding Family of Eucaryotic Na+/H+Exchangers

2000 • 370 citations

The oligopeptide transporter (Pept-1) in human intestine: Biology and function

1997 • 337 citations

Peptide Transporters in the Intestine and the Kidney

1996 • 297 citations

NHE2 and NHE3 are human and rabbit intestinal brush-border proteins

1996 • 274 citations

Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger

1993 • 267 citations

NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins

1998 • 252 citations

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2

1990 • 224 citations

Is intestinal peptide transport energized by a proton gradient?

1985 • 191 citations

Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3

1995 • 153 citations

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

1998 • 148 citations

NHERF Associations with Sodium−Hydrogen Exchanger Isoform 3 (NHE3) and Ezrin Are Essential for cAMP-Mediated Phosphorylation and Inhibition of NHE3

2000 • 137 citations

Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes.

1993 • 136 citations

Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

1995 • 122 citations

Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity

1997 • 120 citations

Dipeptide transporters in apical and basolateral membranes of the human intestinal cell line Caco-2

1993 • 116 citations

Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA

2000 • 114 citations

Enteric nervous system

1989 • 95 citations

Function and Molecular Structure of Brush Border Membrane Peptide/H + Symporters

1996 • 89 citations

Protein absorption : development and present state of the subject

1990 • 85 citations

H+/solute-induced intracellular acidification leads to selective activation of apical Na+/H+ exchange in human intestinal epithelial cells

1999 • 85 citations

Effect of vasoactive intestinal polypeptide (VIP) antagonism on rat jejunal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins

2000 • 81 citations

Angiotensin‐converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco‐2) cells

1995 • 78 citations

The effect of Escherichia coli STa enterotoxin and other secretagogues on mucosal surface pH of rat small intestine in vivo

1988 • 69 citations

Selective inhibition of the Na + /H + exchanger type 3 activates CO 2 /H + -sensitive medullary neurones

1999 • 69 citations

Extracellular pH regulation in microdomains of colonic crypts: effects of short-chain fatty acids.

1995 • 65 citations

The intestinal peptide carrier: A potential transport system for small peptide derived drugs

1996 • 62 citations

The effect of amino acids and dipeptides on sodium and water absorption in man

1973 • 62 citations

Protein absorption: Development and present state of the subject

1991 • 60 citations

Kinetics and regulation of a polarized Na(+)-H+ exchanger from Caco-2 cells, a human intestinal cell line

1991 • 58 citations

Inhibition of the H+/Peptide Cotransporter in the Human Intestinal Cell Line Caco-2 by Cyclic AMP

1996 • 49 citations

Kinetics and Characteristics of Absorption From an Equimolar Mixture of 12 Glycyl-Dipeptides in Human Jejunum

1986 • 48 citations

pH heterogeneity at intracellular and extracellular plasma membrane sites in HT29-C1 cell monolayers

2000 • 43 citations

Demonstration and modification of intervillous pH profiles in rat small intestine in vitro

1989 • 39 citations

VIII. Absorption and secretion of ions in the gastrointestinal tract

2000 • 38 citations

Cloning and Characterization of a pH-Sensing Regulatory Factor That Modulates Transport Activity of the Human H+/Peptide Cotransporter, PEPT1

1997 • 35 citations

Polarized Na+/H+ exchange function is pliable in response to transepithelial gradients of propionate.

1994 • 29 citations

Measurement of Jejunal Surface pH in Situ by Plastic pH Electrode in Patients with Coeliac Disease

1987 • 26 citations

Na+ and H+ transport in human jejunal brush-border membrane vesicles

1988 • 21 citations

Amoxicillin intestinal absorption reduction by amiloride: Possible role of the Na+-H+ exchanger

1995 • 21 citations

Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH

1996 • 19 citations

A Study of Relations between the Absorption of Amino Acids, Dipeptides, Water and Electrolytes in the Normal Human Jejunum

1975 • 18 citations