A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator

Methods in yeast genetics

1979 • 7,824 citations

Protein Kinase C: Structure, Function, and Regulation

1995 • 1,640 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

Origins of Cell Polarity

1996 • 1,024 citations

The Molecular biology of the yeast saccharomyces, life cycle and inheritance

1981 • 636 citations

Phenotypic analysis of temperature-sensitive yeast actin mutants

1985 • 512 citations

Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins.

1993 • 509 citations

The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response.

1995 • 498 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.

1988 • 445 citations

A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle

1990 • 422 citations

A Role for the Transcription Factors Mbp1 and Swi4 in Progression from G1 to S Phase

1993 • 399 citations

A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.

1993 • 373 citations

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect.

1992 • 371 citations

Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane.

1994 • 370 citations

The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast

1991 • 354 citations

A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae.

1995 • 342 citations

Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae.

1995 • 337 citations

Dominant Mutations in a Gene Encoding a Putative Protein Kinase (BCKT) Bypass the Requirement for a Saccharomyces cerevisiae Protein Kinase C Homolog

1992 • 322 citations

The Role of p34 Kinases in the G1 to S-Phase Transition

1992 • 313 citations

Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription

1991 • 313 citations

Rho: theme and variations

1996 • 290 citations

Activation of Yeast Protein Kinase C by Rho1 GTPase

1996 • 286 citations

Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA

1988 • 285 citations

Cell cycle regulted transcription in yeast

1994 • 283 citations

A Second Osmosensing Signal Transduction Pathway in Yeast

1995 • 278 citations

Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity.

1996 • 266 citations

Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.

1984 • 266 citations

Transcription and regulatory signals at the mating type locus in yeast

1984 • 256 citations

SBF Cell Cycle Regulator as a Target of the Yeast PKC-MAP Kinase Pathway

1997 • 247 citations

The SLT2(MPK1) MAP kinase is activated during periods of polarized cell growth in yeast.

1996 • 243 citations

A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.

1992 • 235 citations

Linkage of Replication to Start by the Cdk Inhibitor Sic1

1996 • 230 citations

Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes.

1985 • 220 citations

Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae.

1996 • 208 citations

The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae.

1993 • 197 citations

CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cells.

1995 • 187 citations

The Saccharomyces cerevisiae MADS-Box Transcription Factor Rlm1 Is a Target for the Mpk1 Mitogen-Activated Protein Kinase Pathway

1997 • 187 citations

Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene

1989 • 171 citations

The PCL2 (ORFD)-PHO85 Cyclin-Dependent Kinase Complex: a Cell Cycle Regulator in Yeast

1994 • 164 citations

Cell Cycle Control by a Complex of the Cyclin HCS26 (PCL1) and the Kinase PHO85

1994 • 152 citations

The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start.

1996 • 151 citations

Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC

1994 • 147 citations

Dynamics and organization of MAP kinase signal pathways

1995 • 136 citations

DAF1, a Mutant Gene Affecting Size Control, Pheromone Arrest, and Cell Cycle Kinetics of Saccharomyces cerevisiae

1988 • 130 citations

A pair of functionally redundant yeast genes (PPZ1 and PPZ2) encoding type 1-related protein phosphatases function within the PKC1-mediated pathway.

1993 • 127 citations

A Yeast Mitogen-Activated Protein Kinase Homolog (Mpk1p) Mediates Signalling by Protein Kinase C

1993 • 126 citations

Activation of CLN1 and CLN2 G₁ Cyclin Gene Expression by BCK2

1995 • 108 citations

Genetic analysis of Cln/Cdc28 regulation of cell morphogenesis in budding yeast.

1993 • 106 citations

A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes

1987 • 100 citations

Regulating the HO endonuclease in yeast

1993 • 99 citations

Protein kinase C in yeast. Characteristics of the Saccharomyces cerevisiae PKC1 gene product

1994 • 89 citations

A pathway in the yeast cell division cycle linking protein kinase C (Pkc1) to activation of Cdc28 at START.

1996 • 75 citations

A Synthetic Lethal Screen Identifies SLK1, a Novel Protein Kinase Homolog Implicated in Yeast Cell Morphogenesis and Cell Growth

1992 • 74 citations

Rme1, a negative regulator of meiosis, is also a positive activator of G1 cyclin gene expression.

1995 • 61 citations

MCB elements and the regulation of DNA replication genes in yeast

1993 • 59 citations

Effect of tunicamycin on cell cycle progression in budding yeast

1987 • 36 citations

Chapter 1 Growth and Handling of Yeasts

1975 • 32 citations

Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle

1992 • 22 citations

A cdc-like autolytic Saccharomyces cerevisiae mutant altered in budding site selection is complemented by SPO12, a sporulation gene

1993 • 16 citations

The sequence of a 30 kb fragment on the left arm of chromosome XV fromSaccharomyces cerevisiae reveals 15 open reading frames, five of which correspond to previously identified genes

1996 • 15 citations