Involvement of NF‐Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene

Orchestrated response: a symphony of transcription factors for gene control

2000 • 763 citations

Myc activates telomerase

1998 • 650 citations

A survey of 178 NF-Y binding CCAAT boxes

1998 • 521 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Role of the CCAAT-binding protein CBF/NF-Y in transcription

1998 • 381 citations

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

1998 • 280 citations

Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter.

1990 • 270 citations

A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable

1988 • 263 citations

The retinoblastoma gene product regulates Sp1-mediated transcription.

1992 • 253 citations

Core promoters: active contributors to combinatorial gene regulation: Figure 1.

2001 • 232 citations

Target Detection Assay (TDA): a versatile procedure to determine DNA blinding sites as demonstrated on SP1 protein

1990 • 229 citations

A variety of DNA-binding and multimeric proteins contain the histone fold motif

1995 • 202 citations

Both Transcriptional and Posttranscriptional Mechanisms Regulate Human Telomerase Template RNA Levels

1999 • 164 citations

Association of human TFIID–promoter complexes with silenced mitotic chromatin in vivo

2001 • 155 citations

NF-Y Is Associated with the Histone Acetyltransferases GCN5 and P/CAF

1998 • 145 citations

CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues

1997 • 127 citations

Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA.

1996 • 121 citations

Functional Regions of Human Telomerase Reverse Transcriptase and Human Telomerase RNA Required for Telomerase Activity and RNA-Protein Interactions

2001 • 117 citations

The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters

2001 • 113 citations

Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1

1999 • 112 citations

Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA.

1996 • 103 citations

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954

2001 • 100 citations

Cell cycle regulation ofcdc25Ctranscription is mediated by the periodic repression of the glutamine-rich activators NF-Y and Sp1

1995 • 98 citations

A serum response element and a binding site for NF-Y mediate the serum response of the human thrombospondin 1 gene.

1993 • 85 citations

Sp3 Represses Transcription When Tethered to Promoter DNA or Targeted to Promoter Proximal RNA

1996 • 83 citations

Sp Family Members and Nuclear Factor-Y Cooperatively Stimulate Transcription from the Rat Pyruvate Kinase M Gene Distal Promoter Region via Their Direct Interactions

2000 • 79 citations

Transcriptional Regulation of the Transforming Growth Factor β Type II Receptor Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y in Human Breast Cancer Cells

2002 • 79 citations

Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization

1998 • 76 citations

Cloning and characterization of human and mouse telomerase RNA gene promoter sequences

1998 • 76 citations

Is small cell lung cancer the perfect target for anti-telomerase treatment?

1999 • 53 citations

Activation of Telomerase RNA Gene Promoter Activity by NF-Y, Sp1, and the Retinoblastoma Protein and Repression by Sp3

2000 • 48 citations

Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter.

2001 • 45 citations

The two activation domains of the CCAAT-binding factor CBF interact with the dTAFII110 component of the Drosophila TFIID complex

1998 • 43 citations

Interactions of the CCAAT-binding Trimer NF-Y with Nucleosomes

1999 • 28 citations

Identification of an essential proximal sequence element in the promoter of the telomerase RNA gene of Tetrahymena thermophila

1999 • 17 citations