An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell death.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Experiments in molecular genetics

1972 • 28,260 citations

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

1985 • 3,185 citations

Lactose genes fused to exogenous promoters in one step using a Mu-lac bacteriophage: in vivo probe for transcriptional control sequences.

1979 • 940 citations

Residual guanosine 3‘,5‘-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations.

1991 • 722 citations

Regulation by proteolysis: energy-dependent proteases and their targets

1992 • 458 citations

Programmed Cell Death in Bacterial Populations

1995 • 333 citations

ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities.

1993 • 317 citations

Clp P represents a unique family of serine proteases.

1990 • 291 citations

Mechanism of postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon.

1986 • 279 citations

Effects of the ccd function of the F plasmid on bacterial growth

1985 • 272 citations

Plasmid Addiction Genes of Bacteriophage P1: doc, which Causes Cell Death on Curing of Prophage, and phd, which Prevents Host Death when Prophage is Retained

1993 • 260 citations

The two-component, ATP-dependent Clp protease of Escherichia coli. Purification, cloning, and mutational analysis of the ATP-binding component.

1988 • 256 citations

Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli.

1993 • 247 citations

Lon‐dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid‐free segregant bacteria

1994 • 232 citations

Overexpression of the relA gene in Escherichia coli

1991 • 229 citations

chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100

1993 • 209 citations

Transcription antitermination by bacteriophage lambda N gene product

1980 • 205 citations

Addiction protein Phd of plasmid prophage P1 is a substrate of the ClpXP serine protease of Escherichia coli.

1995 • 188 citations

Guanosine tetraphosphate inhibits protein synthesis in vivo. A possible protective mechanism for starvation stress in Escherichia coli.

1993 • 188 citations

Two genes, pemK and pemI, responsible for stable maintenance of resistance plasmid R100

1988 • 140 citations

The nucleotide sequence and characterization of the relA gene of Escherichia coli.

1988 • 132 citations

ppGpp-mediated regulation of DNA replication and cell division in Escherichia coli

1995 • 132 citations

Characterization of the relA1 mutation and a comparison of relA1 with new relA null alleles in Escherichia coli

1989 • 128 citations

The parDE Operon of the Broad-host-range Plasmid RK2 Specifies Growth Inhibition Associated with Plasmid Loss

1994 • 125 citations

Mechanism of killer gene activation. Antisense RNA-dependent RNase III cleavage ensures rapid turn-over of the stable Hok, SrnB and PndA effector messenger RNAs

1992 • 119 citations

The ClpP component of Clp protease is the sigma 32-dependent heat shock protein F21.5

1990 • 117 citations

Expression of the genes coding for the Escherichia coli integration host factor are controlled by growth phase, rpoS, ppGpp and by autoregulation

1994 • 116 citations

The stable maintenance system pem of plasmid R100: degradation of PemI protein may allow PemK protein to inhibit cell growth

1992 • 106 citations

[11] Minimizing proteolysis in Escherichia coli: genetic solutions

1990 • 101 citations

Virulence in bacteriophage Mu: a case of trans-dominant proteolysis by the Escherichia coli Clp serine protease.

1992 • 64 citations

Mechanism of post-segregational killing: translation of Hok, SrnB and Pnd mRNAs of plasmids R1, F and R483 is activated by 3′-end processing.

1994 • 59 citations

Structural and functional comparison between the stability systems ParD of plasmid R1 and Ccd of plasmid F

1991 • 32 citations

An additional function for bacteriophage lambda rex: the rexB product prevents degradation of the lambda O protein.

1991 • 30 citations

The F factor of Escherichia coli carries a locus of stable plasmid inheritance stm, similar to the parB locus of plasmid RI

1988 • 26 citations

Frameshifting in the expression of the Escherichia coli trpR gene

1992 • 23 citations

Energy-dependent degradation of lambda O protein in Escherichia coli

1993 • 18 citations