Are drugs targeted at Alzheimer's disease useful? 1. Useful for what?

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

1976 • 1,272 citations

Oral Tetrahydroaminoacridine in Long-Term Treatment of Senile Dementia, Alzheimer Type

1986 • 1,148 citations

Neurotransmitter enzyme abnormalities in senile dementia

1977 • 710 citations

THE CHOLINERGIC HYPOTHESIS—TEN YEARS ON

1986 • 563 citations

Enhancement of memory processes in Alzheimer's disease with multiple- dose intravenous physostigmine

1982 • 266 citations

A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease.

1985 • 150 citations

Current Research in Alzheimer Therapy

1989 • 145 citations

9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current

1987 • 111 citations

Enzyme Inhibiting Action of Tetrahydroaminoacridine and its Structural Fragments

1962 • 56 citations