Interleukin-2 Is a Potent Inhibitor of Ley dig Cell Steroidogenesis*

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

Interleukin-1 Stimulates the Secretion of Hypothalamic Corticotropin-Releasing Factor

1987 • 1,512 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Corticotropin-Releasing Factor-Producing Neurons in the Rat Activated by Interleukin-1

1987 • 1,152 citations

Release of Multiple Hormones by a Direct Action of Interleukin-1 on Pituitary Cells

1987 • 670 citations

Corticotropin-Releasing Activity of Monokines

1985 • 500 citations

Effect of interleukin 2, interferon-gamma, and mitogens on the production of tumor necrosis factors alpha and beta.

1985 • 492 citations

Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets.

1983 • 483 citations

Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis.

1987 • 422 citations

Affinity-purified human Interleukin I is cytotoxic to isolated islets of Langerhans

1986 • 321 citations

Characterization of Insulin and Insulin-Like Growth Factor I Receptors of Purified Leydig Cells and Their Role in Steroidogenesis in Primary Culture: A Comparative Study*

1986 • 212 citations

New Approaches to the Immunotherapy of Cancer Using Interleukin-2

1988 • 202 citations

Interleukin-1 Inhibits Leydig Cell Steroidogenesis in Primary Culture*

1988 • 200 citations

Mechanism of Interleukin-2 Signaling: Mediation of Different Outcomes by a Single Receptor and Transduction Pathway

1989 • 148 citations

Regulation of Leydig Cell Function in Primary Culture by Inhibin and Activin*

1989 • 141 citations

Interleukin-1 Inhibits Luteinization of Porcine Granulosa Cells in Culture

1988 • 125 citations

Direct stimulatory effects of insulin-like growth factor-I on Leydig cell steroidogenesis in primary culture

1986 • 115 citations

Interleukin-1 inhibits follicle stimulating hormone-induced differentiation in rat granulosa cells in vitro

1987 • 114 citations

Clearance rates and systemic effects of intravenously administered interleukin 2 (IL-2) containing preparations in human subjects

1983 • 109 citations

Transforming growth factor-β inhibits Leydig cell steroidogenesis in primary culture

1987 • 102 citations

Mechanism of the Inhibitory Action of Epidermal Growth Factor on Testicular Androgen Biosynthesis in Vitro*

1982 • 93 citations

Monocytes Stimulate Cortisol Production by Cultured Human Adrenocortical Cells

1988 • 88 citations

Effects of interleukins 1, 2 and 3 on follicle-stimulating hormone-induced differentiation of rat granulosa cells

1989 • 85 citations

lnterferon-γ Inhibits Steroidogenesis and Accumulation of mRNA of the Steroidogenic Enzymes P450scc and P450c17 in Cultured Porcine Leydig Cells

1989 • 78 citations

IL-2 regulation of tyrosine kinase activity is mediated through the p70-75 beta-subunit of the IL-2 receptor.

1989 • 65 citations

The Role of Calcium/Phospholipid-Dependent Protein Kinase in Leydig Cell Steroidogenesis*

1985 • 64 citations

Fibroblast Growth Factor Inhibits Luteinizing Hormone-Stimulated Androgen Production by Cultured Rat Testicular Cells*

1988 • 57 citations

Tumor necrosis factor-α enhances inhibitory effects of interleukin-1β on Leydig cell steroidogenesis

1990 • 56 citations

MINIREVIEW: Cytokines: An Expanding Network of Immuno-lnflammatory Hormones

1988 • 54 citations

Adrenocorticotropic hormone-releasing activities of interleukins in a homologous invivo system

1989 • 51 citations

The 75,000-Dalton Interleukin-2 Receptor Transmits a Signal for the Activation of a Tyrosine Protein Kinase

1989 • 32 citations

Release of cytokines during generation of lymphokine-activated killer (LAK) cells by IL-2.

1989 • 30 citations