Multi-level Analysis of Organic Anion Transporters 1, 3, and 6 Reveals Major Differences in Structural Determinants of Antiviral Discrimination
Data up to Jan 2025
Total Citations Per Year
Abstract
References (47)
Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton
2013 • 2,950 citations
Antiviral drugs in current clinical use
2004 • 928 citations
Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney
2001 • 501 citations
Expression Cloning and Characterization of ROAT1
1997 • 428 citations
Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta
2000 • 405 citations
The Antiviral Nucleotide Analogs Cidofovir and Adefovir Are Novel Substrates for Human and Rat Renal Organic Anion Transporter 1
1999 • 345 citations
Transport of organic anions across the basolateral membrane of proximal tubule cells
2003 • 297 citations
Impaired Organic Anion Transport in Kidney and Choroid Plexus of Organic Anion Transporter 3 (Oat3 (Slc22a8)) Knockout Mice
2002 • 284 citations
Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
2001 • 276 citations
Human Organic Anion Transporters and Human Organic Cation Transporters Mediate Renal Antiviral Transport
2002 • 274 citations
Molecular Cloning and Characterization of NKT, a Gene Product Related to the Organic Cation Transporter Family That Is Almost Exclusively Expressed in the Kidney
1997 • 256 citations
Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function
1994 • 241 citations
HUMAN RENAL ORGANIC ANION TRANSPORTER 1 (hOAT1) AND ITS ROLE IN THE NEPHROTOXICITY OF ANTIVIRAL NUCLEOTIDE ANALOGS
2001 • 239 citations
Oxygen and renal metabolism
1997 • 235 citations
Immunolocalization of Multispecific Organic Anion Transporters, OAT1, OAT2, and OAT3, in Rat Kidney
2002 • 231 citations
Decreased Renal Organic Anion Secretion and Plasma Accumulation of Endogenous Organic Anions in OAT1 Knock-out Mice
2005 • 223 citations
Changes in the glycosylation pattern during embryonic development of mouse kidney as revealed with lectin conjugates.
1987 • 182 citations
Renal Transport of Adefovir, Cidofovir, and Tenofovir by SLC22A Family Members (hOAT1, hOAT3, and hOCT2)
2007 • 175 citations
Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition
2004 • 173 citations
Organic anion transporter (Slc22a) family members as mediators of toxicity
2004 • 149 citations
The Cellular Pharmacology of Nucleoside‐ and Nucleotide‐Analogue Reverse‐Transcriptase Inhibitors and Its Relationship to Clinical Toxicities
2004 • 143 citations
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.
2000 • 130 citations
A comparison of rhodamine 123 accumulation and efflux in cells with P-glycoprotein-mediated and MRP-associated multidrug resistance phenotypes
1994 • 127 citations
Physiology of Renal Hypoxiaa
1994 • 101 citations
Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa
2004 • 99 citations
Structural Variation Governs Substrate Specificity for Organic Anion Transporter (OAT) Homologs
2007 • 87 citations
Glucose metabolism in renal tubular function
1986 • 82 citations
A Novel Putative Transporter Maps to the Osteosclerosis (oc) Mutation and Is Not Expressed in theocMutant Mouse
1999 • 80 citations
The Molecular Pharmacology of Organic Anion Transporters: from DNA to FDA?
2004 • 80 citations
Mediators of Ischemic Renal Injury
1988 • 78 citations
Fluorescence-Based Assay for the Interaction of Small Molecules with the Human Renal Organic Anion Transporter 1
2000 • 73 citations
In Vitro Cytotoxicity and Mitochondrial Toxicity of Tenofovir Alone and in Combination with Other Antiretrovirals in Human Renal Proximal Tubule Cells
2006 • 67 citations
Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models
2006 • 66 citations
Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions
2006 • 65 citations
Review:Mixing New Cocktails: Drug Interactions in Antiretroviral Regimens
2005 • 51 citations
Integrated physiology of proximal tubular organic anion transport
2005 • 43 citations
NBD-TMA: a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules
2000 • 42 citations
Novel aspects of renal organic anion transporters
2003 • 40 citations
Mitochondrial DNA replication, nucleoside reverse-transcriptase inhibitors, and AIDS cardiomyopathy
2003 • 40 citations
Transfer of antivirals across the human placenta
2005 • 39 citations
Effects of drugs on the fetus
2005 • 24 citations
Confocal imaging of xenobiotic transport across the choroid plexus
2004 • 22 citations
The multidrug resistance in human leukemias. Minireview.
1998 • 14 citations
In Vitro Antiviral Activity of Didanosine Compared with That of Other Dideoxynucleoside Analogs Against Laboratory Strains and Clinical Isolates of Human Immunodeficiency Virus
1993 • 14 citations
Tenofovir Plus Didanosine as Nrti Backbone in HIV-Infected Subjects
2006 • 10 citations
DIGITAL FLUORESCENCE IMAGING OF ORGANIC CATION TRANSPORT IN FRESHLY ISOLATED RAT PROXIMAL TUBULES
2005 • 6 citations
2′,3′-Dideoxycytidine cytotoxicity in human macrophages
1997 • 4 citations
Cited By (0)
No citing papers found in database