Reduced Expression of Insulin-Like Growth Factor-Binding Protein-3 (IGFBP-3) in Squamous Cell Carcinoma Complicating Recessive Dystrophic Epidermolysis Bullosa

Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study

1998 • 2,010 citations

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1998 • 1,850 citations

Cutaneous Squamous-Cell Carcinoma

2001 • 1,247 citations

Insulin, Insulin-Like Growth Factors and Colon Cancer: A Review of the Evidence

2001 • 941 citations

Induction of the growth inhibitor IGF-binding protein 3 by p53

1995 • 884 citations

Insulin-like Growth Factor (IGF)-binding Protein-3 Induces Apoptosis and Mediates the Effects of Transforming Growth Factor-β1 on Programmed Cell Death through a p53- and IGF-independent Mechanism

1997 • 725 citations

Bexarotene Is Effective and Safe for Treatment of Refractory Advanced-Stage Cutaneous T-Cell Lymphoma: Multinational Phase II-III Trial Results

2001 • 685 citations

Plasma Levels of Insulin-Like Growth Factor-I and Lung Cancer Risk: a Case-Control Analysis

1999 • 558 citations

Phase 2 and 3 clinical trial of oral bexarotene (Targretin capsules) for the treatment of refractory or persistent early-stage cutaneous T-cell lymphoma.

2001 • 418 citations

Insulin-Like Growth Factor Binding Proteins in the Human Circulation: A Review

1994 • 346 citations

Direct Functional Interactions between Insulin-like Growth Factor-binding Protein-3 and Retinoid X Receptor-α Regulate Transcriptional Signaling and Apoptosis

2000 • 320 citations

The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.

1994 • 271 citations

Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.

1996 • 257 citations

Transforming Growth Factor- β-induced Cell Growth Inhibition in Human Breast Cancer Cells Is Mediated through Insulin-like Growth Factor-binding Protein-3 Action

1995 • 241 citations

ZIP Kinase, a Novel Serine/Threonine Kinase Which Mediates Apoptosis

1998 • 225 citations

Matrix metalloproteinases as stromal effectors of human carcinoma progression: Therapeutic implications

1997 • 207 citations

INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3 MEDIATES 1α,25-DIHYDROXYVITAMIN D ₃ GROWTH INHIBITION IN THE LNCaP PROSTATE CANCER CELL LINE THROUGH P21/WAF1

2001 • 185 citations

Signalling pathways involved in antiproliferative effects of IGFBP-3: a review

2001 • 168 citations

Epidermolysis bullosa and cancer

2002 • 155 citations

Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.

2002 • 148 citations

Thirty-one cases of Marjolin's ulcer

2003 • 130 citations

Multi-Institutional Phase I/II Trial of Oral Bexarotene in Combination With Cisplatin and Vinorelbine in Previously Untreated Patients With Advanced Non–Small-Cell Lung Cancer

2001 • 127 citations

Laminin-5 in the progression of carcinomas

2001 • 127 citations

Epidermolysis Bullosa: Clinical, Epidemiologic, and Laboratory Advances and the Findings of the National Epidermolysis Bullosa Registry

2000 • 123 citations

Plasma Levels of Insulin-Like Growth Factor-1 and Binding Protein-3, and Their Association With Bladder Cancer Risk

2003 • 122 citations

Multicenter Phase II Study of Oral Bexarotene for Patients With Metastatic Breast Cancer

2003 • 116 citations

DAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancer

2001 • 111 citations

Epidermolysis bullosa complicated by squamous cell carcinoma: report of 10 cases

1992 • 109 citations

Gene Expression Profile Analysis in Human Hepatocellular Carcinoma by cDNA Microarray

2002 • 104 citations

Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer.

2002 • 100 citations

Molecular basis of dystrophic epidermolysis bullosa: Mutations in the type VII collagen gene (COL7A1)

1997 • 99 citations

Regulation of insulin-like growth factor (IGF) II and IGF binding protein 3 autocrine loop in human PC-3 prostate cancer cells by vitamin D metabolite 1,25(OH)2D3 and its analog EB1089.

1998 • 98 citations

Antiproliferative action of tumor necrosis factor-alpha on MCF-7 breastcancer cells is associated with increased insulin-like growth factor binding protein-3 accumulation.

1998 • 96 citations

All-trans-retinoic Acid Increases Transforming Growth Factor-β2 and Insulin-like Growth Factor Binding Protein-3 Expression through a Retinoic Acid Receptor-α-dependent Signaling Pathway

1997 • 94 citations

Human Papillomavirus Type 16 E7 Oncoprotein Binds and Inactivates Growth-Inhibitory Insulin-Like Growth Factor Binding Protein 3

2000 • 91 citations

Nuclear effects: unexpected intracellular actions of insulin-like growth factor binding protein-3

2002 • 84 citations

Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation.

2002 • 81 citations

7S nerve growth factor is an insulin-like growth factor-binding protein protease.

1996 • 56 citations

Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells

2003 • 56 citations

Natural Killer Cell Activity Is Reduced in Patients With Severe Forms of Inherited Epidermolysis Bullosa

1989 • 52 citations

Tissue Stress and Tumor Promotion

1988 • 51 citations

IGFBPs and neoplastic models

1997 • 49 citations

Growth hormone and prostate cancer: guilty by association?

1999 • 47 citations

QUANTITATIVE IMMUNOHISTOCHEMICAL ANALYSIS OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3 IN HUMAN PROSTATIC ADENOCARCINOMA: A PROGNOSTIC STUDY

1998 • 46 citations

Laminin‐γ2 overexpression in head‐and‐neck squamous cell carcinoma

2002 • 44 citations

Role of insulin‐like growth factor binding protein‐3 in breast cancer cell growth

2002 • 43 citations

Relationship between the expression of differentiation‐specific keratins 1 and 10 and cell proliferation in epidermal tumors

1992 • 38 citations

Filaggrin distribution in keratoacanthomas and squamous cell carcinoma.

1984 • 37 citations

Recessive dystrophic epidermolysis bullosa skin displays a chronic growth-activated immunophenotype. Implications for carcinogenesis.

1990 • 36 citations

Differential Stromal Regulation of MMP-1 Expression in Benign and Malignant Keratinocytes

2001 • 35 citations

Insulin-like growth factor I and prostate cancer

2001 • 33 citations

Matrix metalloproteinases in squamous cell carcinoma.

2000 • 31 citations

Patients with severe forms of inherited epidermolysis bullosa exhibit decreased lymphokine and monokine production

1990 • 31 citations

Upregulation of P‐cadherin expression in the lesional skin of pemphigus, Hailey‐Hailey disease and Darier’s disease

2001 • 31 citations

Recessive Dystrophic Epidermolysis Bullosa Skin Displays a Chronic Growth-Activated Immunophenotype

1990 • 29 citations

Isolation and characterization of plasmin-generated bioactive fragments of IGFBP-3

1999 • 20 citations

Comprehensive analysis of gene expression profiles in keratinocytes from patients with generalized atrophic benign epidermolysis bullosa

2002 • 7 citations