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Clinical Pharmacology of Local Anesthetics

Data up to Jan 2025

Published2005
Citations20
References47

Total Citations Per Year

Abstract

References (47)

Polymer microspheres for controlled drug release

2004 • 1,279 citations

Effects of Perioperative Analgesic Technique on the Surgical Outcome and Duration of Rehabilitation after Major Knee Surgery

1999 • 1,079 citations

Molecular Mechanisms of Local Anesthesia

1990 • 840 citations

Local Anesthetics and the Inflammatory Response

2000 • 647 citations

Neutrophil Priming: Pathophysiological Consequences and Underlying Mechanisms

1998 • 359 citations

Intravenous Lidocaine Speeds the Return of Bowel Function, Decreases Postoperative Pain, and Shortens Hospital Stay in Patients Undergoing Radical Retropubic Prostatectomy

1998 • 306 citations

Intravenous Lidocaine Speeds the Return of Bowel Function, Decreases Postoperative Pain, and Shortens Hospital Stay in Patients Undergoing Radical Retropubic Prostatectomy

1998 • 242 citations

The Acute Myotoxic Effects of Bupivacaine and Ropivacaine After Continuous Peripheral Nerve Blockades

2003 • 219 citations

Cerebral protection by lidocaine during cardiac operations

1999 • 197 citations

The in vivo and ultrastructural effects of injection of lysophosphatidyl choline into myelinated peripheral nerve fibres of the adult mouse

1971 • 194 citations

Prolonged Regional Nerve Blockade

1996 • 187 citations

A Novel Liposomal Bupivacaine Formulation to Produce Ultralong-Acting Analgesia

2004 • 159 citations

Prolonged Intercostal Nerve Blockade in Sheep Using Controlled-release of Bupivacaine and Dexamethasone from Polymer Microspheres

1998 • 152 citations

Experimental incision-induced pain in human skin: effects of systemic lidocaine on flare formation and hyperalgesia

2002 • 129 citations

Epidural administration of liposome associated bupivacaine for the management of postsurgical pain: A first study

1994 • 125 citations

Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres

2003 • 119 citations

EMLA reduces acute and chronic pain after breast surgery for cancer

2000 • 118 citations

Local Anesthetic Inhibition of G Protein-Coupled Receptor Signaling by Interference with Gαq Protein Function

2001 • 106 citations

Time-dependent Inhibition of G Protein–coupled Receptor Signaling by Local Anesthetics

2004 • 104 citations

Amitriptyline for Prolonged Cutaneous Analgesia in the Rat

2002 • 103 citations

Prospective comparison of continuous femoral nerve block with nonstimulating catheter placement versus stimulating catheter-guided perineural placement in volunteers ,

2004 • 95 citations

Polyethylene Glycol-Liposomal Doxorubicin

2002 • 91 citations

Neuroprotective Effect of Low-dose Lidocaine in a Rat Model of Transient Focal Cerebral Ischemia

2001 • 89 citations

INTRAVENOUS LIGNOCAINE IN PREVENTION OF DEEP VENOUS THROMBOSIS AFTER ELECTIVE HIP SURGERY

1977 • 84 citations

The Cardiotoxicity of Local Anesthetics: The Place of Ropivacaine

2001 • 80 citations

Potential Neurotoxicity of Spinal Anesthesia With Lidocaine

2000 • 74 citations

EMLA Reduces Acute and Chronic Pain After Breast Surgery for Cancer

2000 • 72 citations

Use of liposome‐associated bupivacaine in a cancer pain syndrome

1996 • 62 citations

The Holy Grail: long-acting local anaesthetics and liposomes

2002 • 61 citations

Long-term chemotherapy of HIV-associated Kaposi's sarcoma with liposomal doxorubicin

2001 • 50 citations

Inhibition of Mammalian Gq Protein Function by Local Anesthetics

2002 • 46 citations

Effects of Delayed Administration of Low-dose Lidocaine on Transient Focal Cerebral Ischemia in Rats

2002 • 43 citations

Outcome after regional anaesthesia in the ambulatory setting – is it really worth it?

2002 • 42 citations

The poor man's epidural: systemic local anesthetics for improving postoperative outcomes

2004 • 41 citations

Neurotoxicological Assessment After Intracisternal Injection of Liposomal Bupivacaine in Rabbits

1997 • 39 citations

WHY DON'T WE TELL?

1964 • 36 citations

Bupivacaine in microcapsules prolongs analgesia after subcutaneous infiltration in humans: a dose-finding study.

2004 • 36 citations

Prospective Comparison of Continuous Femoral Nerve Block with Nonstimulating Catheter Placement Versus Stimulating Catheter-Guided Perineural Placement in Volunteers

2004 • 34 citations

N -Phenylethyl Amitriptyline in Rat Sciatic Nerve Blockade

2002 • 34 citations

Neurotoxicological Assessment After Intracisternal Injection of Liposomal Bupivacaine in Rabbits

1997 • 33 citations

Drug Delivery System of Anti-fungal and Parasitic Agents

2002 • 31 citations

Novel local anaesthetics and novel indications for local anaesthetics

2001 • 30 citations

Liposomal Bleomycin: Increased Therapeutic Activity and Decreased Pulmonary Toxicity in Mice

2001 • 29 citations

Major surgery in the ambulatory environment: continuous catheters and home infusions

2002 • 27 citations

Effects of Antidepressants on Function and Viability of Human Neutrophils

2003 • 26 citations

Liposomal amphotericin B treatment for rhinocerebral mucormycosis: how much is enough?

2003 • 22 citations

Motor blockade and absence of local nerve toxicity induced by liposomal bupivacaine injected into the brachial plexus of rabbits.

1995 • 22 citations

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