The localization and assay of chemical elements by microprobe methods

Introduction to Analytical Electron Microscopy

1979 • 1,316 citations

XCIII. On the theory of X-ray absorption and of the continuous X-ray spectrum

1923 • 1,071 citations

Physical Techniques in Biological Research

1963 • 941 citations

Transport of ions and water in animals

1977 • 481 citations

Electron microscopy of frozen water and aqueous solutions

1982 • 459 citations

VITRIFICATION OF PURE WATER FOR ELECTRON MICROSCOPY

1981 • 435 citations

The electron microprobe

1967 • 380 citations

Quantitative electron probe microanalysis of biological thin sections: Methods and validity

1976 • 365 citations

Physical Aspects of Electron Microscopy and Microbeam Analysis

1976 • 360 citations

The microanalysis of light elements using transmitted energy loss electrons

1975 • 312 citations

The Efficiency of Production of Characteristic X-radiation in Thick Targets of a Pure Element

1961 • 304 citations

Electron microscopy of frozen hydrated biological specimens

1976 • 290 citations

Electron microscopy of frozen hydrated sections of vitreous ice and vitrified biological samples

1983 • 284 citations

Elemental distribution in striated muscle and the effects of hypertonicity: Electron probe analysis of cryo sections

1977 • 269 citations

Electron probe analysis of vascular smooth muscle. Composition of mitochondria, nuclei, and cytoplasm.

1979 • 263 citations

Microbeam Analysis 1984

1984 • 238 citations

Electron microscopy of frozen biological suspensions

1983 • 231 citations

Radiation damage relative to transmission electron microscopy of biological specimens at low temperature: a review

1978 • 226 citations

High-resolution microanalysis of biological specimens by electron energy loss spectroscopy and by electron spectroscopic imaging

1980 • 216 citations

A high-sensitivity laser microprobe mass analyzer

1975 • 196 citations

Physical aspects of electron microscopy and microbeam analysis

1976 • 175 citations

Biological X-Ray Microanalysis

1979 • 170 citations

Formulae for light-element micro analysis by electron energy-loss spectrometry

1978 • 168 citations

Radiation damage in the high resolution electron microscopy of biological materials: A review*

1978 • 137 citations

Preparation of freeze-dried cryosections for quantitative X-ray microanalysis of electrolytes in biological soft tissues

1978 • 135 citations

Microbeam Analysis in Biology

1979 • 132 citations

A cryostat approach to ultrathin ‘dry’ frozen sections for electron microscopy: a morphological and X-ray analytical study

1974 • 121 citations

About the use of electron energy-loss spectroscopy for chemical mapping of thin foils with high spatial resolution

1978 • 118 citations

Beam‐induced loss of organic mass under electron‐microprobe conditions

1974 • 112 citations

Microprobe measurement of Na, K and Cl concentration profiles in epithelial cells and intercellular spaces of rabbit ileum

1978 • 110 citations

Application of scanning electron microscopy to x-ray analysis of frozen-hydrated sections. I. Specimen handling techniques.

1981 • 109 citations

Microprobe Analysis of Biological Systems

1981 • 104 citations

Electron probe microanalysis in biology

1978 • 104 citations

Novel role of calcium in exocytosis: mechanism of nematocyst discharge as shown by x-ray microanalysis.

1981 • 102 citations

The single-scattering model and spatial resolution in X-ray analysis of thin foils

1982 • 97 citations

Mass thickness determination by electron energy loss for quantitative X‐ray microanalysis in biology

1984 • 94 citations

Quantitative analysis of electrolytes in frozen dried sections

1982 • 91 citations

THE ELEMENTARY COMPOSITION OF ORGANIC OBJECTS AFTER ELECTRON IRRADIATION.

1965 • 90 citations

Quantification for the X‐ray microanalysis of cryosections

1982 • 90 citations

Energy dispersive X-ray microanalysis of the electrolytes in biological bulk specimen

1977 • 90 citations

Quantitative Electron Microprobe Analysis

1965 • 88 citations

Electron Microprobe and Ion-Selective Microelectrode Studies of Fluid Secretion in the Salivary Glands of Calliphora

1978 • 88 citations

Intracellular Na+:K+ ratios in human cancer cells as revealed by energy dispersive x-ray microanalysis.

1981 • 86 citations

PHYSICAL TECHNIQUES IN BIOLOGICAL RESEARCH

1962 • 83 citations

Applications of secondary ion mass spectrometry (SIMS) in biological research: a review

1982 • 80 citations

The X-ray microanalysis of frozen-hydrated sections in scanning electron microscopy: An evaluation

1981 • 75 citations

Der Einfluß tiefer Temperaturen auf die Strahlenschädigung von organischen Kristallen durch 100 keV-Elektronen / The Influence of Very Low Temperature on the Radiation Damage of Organic Crystals Irradiated by 100 keV-Electrons

1972 • 74 citations

Parallel recording of electron energy loss spectra

1981 • 73 citations

Quantitative electron probe X-ray microanalysis of electrolyte elements within epithelial tissue compartments.

1979 • 66 citations

Cryo‐ultramicrotomy and myofibrillar fine structure: a review

1977 • 66 citations

Spatial resolution and detection sensitivity in microanalysis by electron energy loss selected imaging

1981 • 65 citations

Electron scattering in ice and organic materials

1982 • 64 citations

Intracellular calcium store and transport of elements in acinar cells of the salivary gland determined by electron probe X-ray microanalysis.

1983 • 59 citations

Cryoultramicrotomy: evidence against melting and the use of a low temperature cement for specimen orientation

1982 • 57 citations

Chemical measurements of radiation damage in organic samples at and below room temperature

1980 • 57 citations

Optimizing thin film X‐ray spectra for quantitative analysis

1982 • 56 citations

Freeze-substitution as a preparation technique for biological X-ray microanalysis.

1980 • 56 citations

Contribution to the contamination problem in transmission electron microscopy

1978 • 55 citations

Structural evidence that botulinum toxin blocks neuromuscular transmission by impairing the calcium influx that normally accompanies nerve depolarization.

1981 • 52 citations

Specimen contamination in analytical electron microscopy: Sources and solutions

1978 • 48 citations

Standards for quantitative energy dispersive X‐ray microanalysis of biological cryosections: validation and application to studies of myocardium

1983 • 48 citations

ELECTRON‐PROBE X‐RAY MICROANALYSIS: TECHNIQUES AND RECENT APPLICATIONS IN BIOLOGY

1981 • 47 citations

PROBLEMS OF THE CONTINUUM-NORMALIZATION METHOD FOR THE QUANTITATIVE ANALYSIS OF SECTIONS OF SOFT TISSUE

1979 • 45 citations

Intracellular water and dry mass content as measured in bulk specimens by energy-dispersive X-ray microanalysis

1982 • 45 citations

Energy dispersive X-ray microanalysis of the electrolytes in biological bulk specimen

1977 • 45 citations

Organic mass loss at 100 K and 300 K

1982 • 44 citations

Sources of contamination in electron optical equipment

1981 • 43 citations

The X-ray scanning microanalyser

1959 • 43 citations

The Basic Principles of Electron Energy Loss Spectroscopy

1979 • 42 citations

Electron energy loss spectroscopy: Detectable limits for elemental analysis

1980 • 40 citations

Instrumentation for direct observation of frozen hydrated specimens in the electron microscope

1978 • 40 citations

Microbeam Analysis in Biology

1982 • 39 citations

Microprobe analysis of biological systems

1981 • 39 citations

CONTRAST AND MASS THICKNESS.

1965 • 37 citations

Preparation of Biological Material For X-Ray Microanalysis of Diffusible Elements

1978 • 37 citations

Background determination in X-ray microanalysis of biological thin sections

1980 • 36 citations

Improved spatial resolution microanalysis in a scanning transmission electron microscope

1977 • 35 citations

Concerning the nature of the cryosectioning process

1982 • 35 citations

Measurement of partial specific thickness (net thickness) of critical-point-dried cultured fibroblast by energy analysis

1981 • 34 citations

Electron probe x-ray analysis of single ferritin molecules.

1976 • 34 citations

Ionic distribution in dopamine-stimulated NaCl fluid-secreting cockroach salivary glands

1983 • 32 citations

Problems in quantitative x-ray microanalysis of biological specimens.

1980 • 32 citations

Electron Beam Heating Temperature Profiles in Moderately Thick Cold Stage STEM/SEM Specimens

1978 • 30 citations

The quantitation of electron energy loss spectra

1981 • 30 citations

Energy Loss Spectrometry for Biological Research

1979 • 30 citations

Epithelial ions and transport: Application of biophysical techniques

1983 • 29 citations

Concentration of elements in mitotic chromatin as measured by x-ray microanalysis.

1977 • 29 citations

An electron microprobe study of the influence of beam current density on the stability of detectable elements in mixed‐salts (isoatomic) microdroplets

1982 • 28 citations

Post-mortem elemental redistribution in rat studied by X-ray microanalysis and electron microscopy

1980 • 27 citations

Oil contamination with the SEM operated in the spot scanning mode

1975 • 27 citations

INTIMAL CHANGES IN VENOUS STASIS. AN ELECTRON MICROSCOPIC STUDY.

1965 • 25 citations

Quantitative electron probe microanalysis of biological thin sections: the use of stem for measurement of local mass thickness

1978 • 24 citations

Cryoultramicrotomy as a Preparative Method for X-ray Microanalysis in Pathology

1982 • 23 citations

Electron probe X-ray microanalysis of calcium and other elements in meiotic spindles, in frozen sections of spermatocytes from crane fly testes

1980 • 22 citations

THE ROLE OF FAST SECONDARY ELECTRONS IN DEGRADING SPATIAL RESOLUTION IN THE ANALYTICAL ELECTRON MICROSCOPE

1982 • 20 citations

A cooling chain for studies of cryofixed biological specimens by scanning transmission electron microscopy and X-ray microanalysis

1981 • 16 citations

The laser microprobe mass analyser (LAMMA): biomedical applications.

1978 • 13 citations

Cryoultramicrotomy as a preparation method for x-ray microanalysis.

1980 • 13 citations

Electron energy loss chemical mapping of low Z elements in biological sections.

1983 • 10 citations

Scanning electron microscopy

1978 • 9 citations

FROZEN‐HYDRATED AND DRYING THIN CRYO‐SECTIONS OBSERVED IN STEM

1982 • 9 citations

Electron probe analysis of microdroplets: Factors affecting the proportionality between measured X‐ray intensity and concentration

1981 • 8 citations

Quantitative Electron Microprobe Analysis

1968 • 8 citations

Quantitative EPMA of biological tissue using mixtures of salts as standards.

1981 • 8 citations

ELECTRON ENERGY-LOSS ANALYSIS IN BIOLOGY: APPLICATION TO MUSCLE AND A PARALLEL COLLECTION SYSTEM

1981 • 7 citations

Parallel recording of electron energy loss spectra

1981 • 7 citations

X-RAY MICROANALYSIS OF FREEZE-DRIED MUSCLE: TECHNIQUES AND PROBLEMS

1981 • 6 citations

ELECTRON ENERGY-LOSS MICROANALYSIS WITH HIGH SPATIAL RESOLUTION, ENERGY RESOLUTION, AND SENSITIVITY

1981 • 5 citations

Oil contamination with the SEM operated in the spot scanning mode

1975 • 3 citations

Progress in electron energy loss analysis for biological specimens.

1980 • 3 citations