PROTECTIVE EFFECTS OF DIETARY L-ARGININE SUPPLEMENTATION ON CHRONIC CYCLOSPORINE NEPHROTOXICITY1

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Nitric oxide synthase in macula densa regulates glomerular capillary pressure.

1992 • 531 citations

The long-term course of cyclosporine-associated chronic nephropathy

1988 • 521 citations

Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy

1996 • 443 citations

Expression of nitric oxide synthase in kidney macula densa cells

1992 • 296 citations

Pathogenesis of cyclosporine nephropathy

1995 • 250 citations

Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat.

1992 • 248 citations

Endothelium-derived relaxing factor/nitric oxide modulates angiotensin II action in the isolated microperfused rabbit afferent but not efferent arteriole.

1993 • 194 citations

Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506

1996 • 192 citations

SYNERGISTIC EFFECTS OF CYCLOSPORINE AND RAPAMYCIN IN A CHRONIC NEPHROTOXICITY MODEL1

1996 • 133 citations

Arginine feeding modifies cyclosporine nephrotoxicity in rats.

1993 • 124 citations

Cyclosporine A induced arteriolopathy in a rat model of chronic cyclosporine nephropathy

1995 • 109 citations

Mechanisms of the endothelial toxicity of cyclosporin A. Role of nitric oxide, cGMP, and Ca2+.

1994 • 92 citations

Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity

1994 • 90 citations

A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine

1995 • 63 citations

Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity.

1995 • 61 citations

SUPPRESSION OF NITRIC OXIDE PRODUCTION BY CYCLOSPORIN A AND FK506A IN RAT VASCULAR SMOOTH MUSCLE CELLS

1994 • 40 citations

Experimental nephrotoxicity, hepatotoxicity and pharmacokinetics of cyclosporin G versus cyclosporin A

1994 • 34 citations

Coordinate changes in C protein and myosin expression during skeletal muscle hypertrophy

1994 • 32 citations

CLINICALLY RELEVANT DOSES AND BLOOD LEVELS PRODUCE EXPERIMENTAL CYCLOSPORINE NEPHROTOXICITY WHEN COMBINED WITH NITRIC OXIDE INHIBITION1

1996 • 30 citations

Cyclosporine inhibits the renal response to L-arginine in human kidney transplant recipients.

1995 • 30 citations