Interaction of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride with nucleic acids and proteins

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

1954 • 3,832 citations

QUALITATIVE AND QUANTITATIVE COLORIMETRIC DETERMINATION OF HEPTOSES

1953 • 520 citations

The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

1967 • 177 citations

Interrelationships of some chemical, physicochemical, and biological activities of several 1-(2-haloethyl)-1-nitrosoureas.

1974 • 139 citations

Interaction of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) with nucleic acids and proteins in vivo and in vitro.

1972 • 122 citations

The covalent binding of metabolites of dimethylaminoazobenzene, β‐naphthylamine and aniline to nucleic acids in vivo

1966 • 77 citations

2-chloroethanol formation as evidence for a 2-chloroethyl alkylating intermediate during chemical degradation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.

1975 • 71 citations

A structure-activity analysis of chemical and biological parameters of chloroethylnitrosoureas in mice.

1977 • 70 citations

Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media

1975 • 64 citations

Carbamoylation of amino acid, peptides, and proteins by nitrosoureas.

1975 • 57 citations

Chemistry of nitrosoureas. Decomposition of deuterated 1,3-bis(2-chloroethyl)-1-nitrosourea

1976 • 45 citations

Chemistry and structure-activity studies of the nitrosoureas.

1976 • 41 citations

Modification of proteins by 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (nsc 79037) in vitro.

1973 • 39 citations

Effect of 3-[4-amino-2-methyl-5-pyrimidinyl)ethyl[-1(2-chloroethyl)-1-nitrosourea hydrochloride on lymphoid leukemia L-1210.

1975 • 26 citations

Mechanism of Action of Nitrosoureas

1975 • 26 citations

Structures of the decomposition products of chlorozotocin: new intramolecular carbamates of 2-amino-2-deoxyhexoses

1981 • 17 citations

Antileukemic Agents. III. Synthesis and Antitumor Activity of N-(2-Chloroethyl)-N-nitrosourea Derivatives

1974 • 17 citations

Effects of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) and its degradation products on progression of L1210 cells through the cell cycle.

1971 • 13 citations

Antitumor activity of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride in a variety of experimental tumors.

1978 • 12 citations

In vitro metabolism of ACNU, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosourea hydrochloride, a water-soluble antitumor nitrosourea.

1985 • 9 citations

Evaluation of the alkylating activity of nitrosoureas by thin-layer densitometry

1979 • 9 citations

Whole-body autoradiographic studies on tissue distribution of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride in tumor-bearing mice and rats.

1978 • 8 citations

Identification of major urinary metabolites of ACNU, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosourea hydrochloride in rats.

1985 • 6 citations

ChemInform Abstract: CHEMISTRY OF NITROSOUREAS. DECOMPOSITION OF DEUTERATED 1,3‐BIS(2‐CHLOROETHYL)‐1‐NITROSOUREA

1976 • 5 citations

Phase I Study of 1-(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl-3-(2-Chloroethyl)-3-Nitrosourea Hydrochloride (ACNU)

1976 • 1 citations