Molecular Cloning of the Rat Metallothionein 1 (MT-1) mRNA Sequence

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells

1979 • 1,454 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

A CADMIUM PROTEIN FROM EQUINE KIDNEY CORTEX

1957 • 1,295 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Metallothionein: a Cadmium and Zinc-containing Protein from Equine Renal Cortex

1961 • 685 citations

Transcriptional regulation of the mouse metallothionein-I gene by heavy metals.

1981 • 601 citations

Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynudeotidyl transferase

1976 • 416 citations

The rat serum albumin gene: analysis of cloned sequences.

1979 • 400 citations

5′-Terminal sequences of eucaryotic mRNA can be cloned with high efficiency

1981 • 367 citations

Filter replicas and permanent collections of recombinant DNA plasmids

1979 • 355 citations

Structure of mouse metallothionein-I gene and its mRNA

1981 • 301 citations

Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids

1981 • 284 citations

Human hepatic metallothioneins

1974 • 238 citations

Isolation and characterization of the mouse metallothionein-I gene.

1980 • 210 citations

An improved method for detecting foreign DNA in plasmids of Escherichia coli

1979 • 183 citations

Isolation and characterization of metallothionein which is highly concentrated in newborn rat liver.

1979 • 170 citations

Preparation and properties of the major copper-binding component in human fetal liver. Its identification as metallothionein.

1978 • 169 citations

Zinc accumulation and metabolism in primary cultures of adult rat liver cells. Regulation by glucocorticoids

1978 • 167 citations

Human fetal liver contains both zinc- and copper-rich forms of metallothionein.

1980 • 145 citations

Metallothionein occurs in roots of Agrostis tolerant to excess copper

1980 • 138 citations

Dexamethasone Stimulation of Metallothionein Synthesis in HeLa Cell Cultures

1979 • 131 citations

Regulation of liver metallothionein and plasma zinc by the glucocorticoid dexamethasone

1979 • 130 citations

Distribution of copper and zinc in the liver of the developing sheep foetus

1977 • 112 citations

Human metallothionein genes: molecular cloning and sequence analysis of the mRNA

1982 • 102 citations

Partial purification, characterization and translation in vitro of rat liver metallothionein messenger ribonucleic acid

1978 • 80 citations

Turnover of metallothioneins in rat liver

1978 • 70 citations

Potentiation of hemoglobin messenger ribonucleic acid. A step in protein synthesis initiation involving interaction of messenger with 18 S ribosomal ribonucleic acid.

1975 • 60 citations

Physiological parameters of prokaryotic metallothionein induction

1980 • 58 citations

Native metallothionein levels in rat hepatic cytosol during perinatal development

1979 • 55 citations

Partitioning of zinc and copper in fetal liver subfractions: Appearance of metallothionein-like proteins during development

1981 • 46 citations

Glucocorticoid hormone receptor mediated induction of metallothionein synthesis in HeLa cells

1980 • 40 citations

The Influence of Zinc on the Ontogeny of Hepatic Metallothionein in the Fetal Rat

1981 • 31 citations