Acute alteration of chloroform-induced hepato- and nephrotoxicity by n-hexane, methyl n-butyl ketone, and 2,5-hexanedione

A Colorimetric Method for the Determination of Serum Glutamic Oxalacetic and Glutamic Pyruvic Transaminases

1957 • 9,675 citations

THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN 1

1945 • 1,598 citations

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism.

1973 • 1,467 citations

Method for the Quantitative Morphologic Analysis of Tissues

1943 • 979 citations

Glutathione: Metabolism and function

1978 • 971 citations

RENAL TUBULAR TRANSPORT: ACCUMULATION OF P-AMINOHIPPURATE BY RABBIT KIDNEY SLICES

1950 • 407 citations

A Specific and Reasonably Accurate Method for Routine Determination of Plasma Triglyceride

1960 • 335 citations

The effect of diet and 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) on microsomal hydroxylating enzymes and on sensitivity of rats to carbon tetrachloride poisoning

1966 • 327 citations

The effect of some carbonyl compounds on rat liver glutathione levels

1970 • 264 citations

Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species.

1975 • 260 citations

Characterization of the metabolites of methyl n-butyl ketone, methyl iso-butyl ketone, and methyl ethyl ketone in guinea pig serum and their clearance

1976 • 245 citations

Relative effects of various chlorinated hydrocarbons on liver and kidney function in mice

1966 • 227 citations

Increased susceptibility to carbon tetrachloride poisoning in the rat after pretreatment with oral phenobarbitone

1969 • 216 citations

Phosgene: A metabolite of chloroform

1977 • 208 citations

Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450

1977 • 199 citations

Chloroform toxicity in mice: Correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules

1973 • 177 citations

Differences in the potentiation of carbon tetrachloride in rats by ethanol and isopropanol pretreatment

1971 • 146 citations

Synergistic effects of phorone on the hepatotoxicity of bromobenzene and paracetamol in mice

1978 • 128 citations

Enzymes catalysing conjugations of glutathione with αβ-unsaturated carbonyl compounds

1968 • 126 citations

METABOLISM OF CARBON TETRACHLORIDE AND CHLOROFORM BY THE RAT.

1963 • 122 citations

Evidence for phosgene formation during liver microsomal oxidation of chloroform

1977 • 118 citations

Mechanisms of Acute Hepatic Toxicity

1974 • 117 citations

Cytochrome P450K of rat kidney cortex microsomes: Its Involvement in fatty acid ω- and (ω-1)-hydroxylation

1972 • 114 citations

The role of glutathione in chloroform-induced hepatotoxicity

1976 • 104 citations

Potentiation of Carbon Tetrachloride Toxicity by Aliphatic Alcohols

1967 • 97 citations

Relationship of alcohol metabolism to the potentiation of CCl 4 hepatotoxicity induced by aliphatic alcohols.

1972 • 85 citations

Chlorinated Hydrocarbon Toxicity

1974 • 72 citations

Sensitivity of several serum enzymes for the detection of thioacetamide-, dimethylnitrosamine- and diethanolamine-induced liver damage in rats

1973 • 70 citations

Structural and functional changes in rat kidney during CCl4 intoxication.

1968 • 67 citations

Enhanced Hepatic Microsomal Activity by Pretreatment of Rats with Acetone or Isopropanol

1973 • 67 citations

Acute alteration of chloroform-induced hepato- and nephrotoxicity by mirex and Kepone

1979 • 66 citations

Selective modification of the renal and the hepatic toxicities of chloroform by induction of drug-metabolizing enzyme systems in kidney and liver.

1978 • 64 citations

Comparative alterations in extrahepatic drug metabolism by factors known to affect hepatic activity

1977 • 62 citations

Potentiation of carbon tetrachloride-induced hepatotoxicity in alloxan- or strepto- zotocin-diabetic rats.

1975 • 49 citations

Metabolism of Carbon Tetrachloride and Chloroform by the Rat

1964 • 48 citations

Effect of n-hexane inhalation on the monooxygenase system in MICE liver microsomes

1974 • 47 citations

MODIFICATION OF THE EFFECTS OF CHLOROFORM ON THE RAT LIVER

1970 • 46 citations

The participation of 2-butanone in 2-butanol-induced potentiation of carbon tetrachloride hepatotoxicity.

1976 • 42 citations

Chloroform toxicity in the mouse: Role of genetic factors and steroids

1979 • 42 citations

The role of metabolism in chloroform hepatotoxicity

1974 • 40 citations

Potentiation of carbon tetrachloride hepatotoxicity in rats by pretreatment with polychlorinated biphenyls

1975 • 40 citations

Polybrominated biphenyl-induced potentiation of chloroform toxicity

1978 • 37 citations

The influence of inhaled ketone solvent vapors on hepatic microsomal biotransformation activities*1

1977 • 36 citations

Potentiation of the Hepatotoxic Responses to Chemicals in Alloxan-Diabetic Rats

1975 • 31 citations

Biotransformation of chloroform by rat and human liver microsomes; in vitro effect on some enzyme activities and mechanism of irreversible binding to macromolecules

1979 • 30 citations

Effect of acetone administered in vivo upon hepatic microsomal drug metabolizing activity in the rat

1974 • 29 citations

The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats.

1975 • 22 citations

Potentiation of carbon tetrachloride-induced hepatotoxicity by 1,3-butanediol

1979 • 22 citations

Effects of renal fuels on uptake of PAH and uric acid by separated renal tubules of the rabbit

1978 • 19 citations

Potentiation of hepatic and renal toxicity of various compounds by prior exposure to polybrominated biphenyls.

1978 • 18 citations

Metabolic studies on renal transport of p-aminohippuratein vitro

1969 • 17 citations

Investigations on metabolic modulation of p-aminohippurate accumulation by rabbit renal cortical slices.

1976 • 11 citations

Urinary excretion of some n-hexane metabolites

1978 • 10 citations

Energy Requirements for Active Transport of p-Aminohippurate in Renal Cortical Slices

1973 • 8 citations

Effects of Medium pH on <i>p</i><i>-</i>Aminohippurate Transport in Rat Kidney Fragments

1978 • 2 citations